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Year Number of Results
2000 1
2002 2
2007 1
2008 3
2009 1
2010 5
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2012 7
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2014 17
2015 13
2016 18
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2018 7
2019 11
2020 6
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Similar Articles for PMID: 29465396

107 results
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A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation.
Ruff EF, Muretta JM, Thompson AR, Lake EW, Cyphers S, Albanese SK, Hanson SM, Behr JM, Thomas DD, Chodera JD, Levinson NM. Ruff EF, et al. Elife. 2018 Feb 21;7:e32766. doi: 10.7554/eLife.32766. Elife. 2018. PMID: 29465396 Free PMC article.
A water-mediated allosteric network governs activation of Aurora kinase A.
Cyphers S, Ruff EF, Behr JM, Chodera JD, Levinson NM. Cyphers S, et al. Nat Chem Biol. 2017 Apr;13(4):402-408. doi: 10.1038/nchembio.2296. Epub 2017 Feb 6. Nat Chem Biol. 2017. PMID: 28166210 Free PMC article.
Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states.
Lake EW, Muretta JM, Thompson AR, Rasmussen DM, Majumdar A, Faber EB, Ruff EF, Thomas DD, Levinson NM. Lake EW, et al. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11894-E11903. doi: 10.1073/pnas.1811158115. Epub 2018 Dec 5. Proc Natl Acad Sci U S A. 2018. PMID: 30518564 Free PMC article.
The multifaceted allosteric regulation of Aurora kinase A.
Levinson NM. Levinson NM. Biochem J. 2018 Jun 26;475(12):2025-2042. doi: 10.1042/BCJ20170771. Biochem J. 2018. PMID: 29946042 Free PMC article. Review.
Dynamics of human protein kinase Aurora A linked to drug selectivity.
Pitsawong W, Buosi V, Otten R, Agafonov RV, Zorba A, Kern N, Kutter S, Kern G, Pádua RA, Meniche X, Kern D. Pitsawong W, et al. Elife. 2018 Jun 14;7:e36656. doi: 10.7554/eLife.36656. Elife. 2018. PMID: 29901437 Free PMC article.
The structure of C290A:C393A Aurora A provides structural insights into kinase regulation.
Burgess SG, Bayliss R. Burgess SG, et al. Acta Crystallogr F Struct Biol Commun. 2015 Mar;71(Pt 3):315-9. doi: 10.1107/S2053230X15002290. Epub 2015 Feb 19. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25760707 Free PMC article.
Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2.
Zorba A, Buosi V, Kutter S, Kern N, Pontiggia F, Cho YJ, Kern D. Zorba A, et al. Elife. 2014 May 27;3:e02667. doi: 10.7554/eLife.02667. Elife. 2014. PMID: 24867643 Free PMC article.
Switching Aurora-A kinase on and off at an allosteric site.
Bayliss R, Burgess SG, McIntyre PJ. Bayliss R, et al. FEBS J. 2017 Sep;284(18):2947-2954. doi: 10.1111/febs.14069. Epub 2017 Apr 18. FEBS J. 2017. PMID: 28342286 Free article. Review.
Bora and Aurora-A continue to activate Plk1 in mitosis.
Bruinsma W, Macurek L, Freire R, Lindqvist A, Medema RH. Bruinsma W, et al. J Cell Sci. 2014 Feb 15;127(Pt 4):801-11. doi: 10.1242/jcs.137216. Epub 2013 Dec 11. J Cell Sci. 2014. PMID: 24338364 Free article.
A novel mechanism for activation of Aurora-A kinase by Ajuba.
Bai M, Ni J, Wu J, Wang B, Shen S, Yu L. Bai M, et al. Gene. 2014 Jun 10;543(1):133-9. doi: 10.1016/j.gene.2014.03.048. Epub 2014 Mar 26. Gene. 2014. PMID: 24680704
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