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The Aspergillus fumigatus Mucin MsbA Regulates the Cell Wall Integrity Pathway and Controls Recognition of the Fungus by the Immune System.

Gurgel ILDS, Jorge KTOS, Malacco NLSO, Souza JAM, Rocha MC, Fernandes MF, Martins FRB, Malavazi I, Teixeira MM, Soriani FM. Gurgel ILDS, et al. mSphere. 2019 Jun 19;4(3):e00350-19. doi: 10.1128/mSphere.00350-19. mSphere. 2019. PMID: 31217305 Free PMC article.

Putative Membrane Receptors Contribute to Activation and Efficient Signaling of Mitogen-Activated Protein Kinase Cascades during Adaptation of Aspergillus fumigatus to Different Stressors and Carbon Sources.

Silva LP, Frawley D, Assis LJ, Tierney C, Fleming AB, Bayram O, Goldman GH. Silva LP, et al. mSphere. 2020 Sep 16;5(5):e00818-20. doi: 10.1128/mSphere.00818-20. mSphere. 2020. PMID: 32938702 Free PMC article.

Aspergillus fumigatus G-Protein Coupled Receptors GprM and GprJ Are Important for the Regulation of the Cell Wall Integrity Pathway, Secondary Metabolite Production, and Virulence.

Filho APDC, Brancini GTP, de Castro PA, Valero C, Ferreira Filho JA, Silva LP, Rocha MC, Malavazi I, Pontes JGM, Fill T, Silva RN, Almeida F, Steenwyk JL, Rokas A, Dos Reis TF, Ries LNA, Goldman GH. Filho APDC, et al. mBio. 2020 Oct 13;11(5):e02458-20. doi: 10.1128/mBio.02458-20. mBio. 2020. PMID: 33051372 Free PMC article.

The Aspergillus fumigatus Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance.

Mattos EC, Silva LP, Valero C, de Castro PA, Dos Reis TF, Ribeiro LFC, Marten MR, Silva-Rocha R, Westmann C, da Silva CHTP, Taft CA, Al-Furaiji N, Bromley M, Mortensen UH, Benz JP, Brown NA, Goldman GH. Mattos EC, et al. mBio. 2020 Feb 4;11(1):e02962-19. doi: 10.1128/mBio.02962-19. mBio. 2020. PMID: 32019798 Free PMC article.

The Aspergillus fumigatus pkcA G579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model.

Rocha MC, Godoy KF, de Castro PA, Hori JI, Bom VL, Brown NA, Cunha AF, Goldman GH, Malavazi I. Rocha MC, et al. PLoS One. 2015 Aug 21;10(8):e0135195. doi: 10.1371/journal.pone.0135195. eCollection 2015. PLoS One. 2015. PMID: 26295576 Free PMC article.

An Ssd1 Homolog Impacts Trehalose and Chitin Biosynthesis and Contributes to Virulence in Aspergillus fumigatus.

Thammahong A, Dhingra S, Bultman KM, Kerkaert JD, Cramer RA. Thammahong A, et al. mSphere. 2019 May 8;4(3):e00244-19. doi: 10.1128/mSphere.00244-19. mSphere. 2019. PMID: 31068436 Free PMC article.

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus.

Voltersen V, Blango MG, Herrmann S, Schmidt F, Heinekamp T, Strassburger M, Krüger T, Bacher P, Lother J, Weiss E, Hünniger K, Liu H, Hortschansky P, Scheffold A, Löffler J, Krappmann S, Nietzsche S, Kurzai O, Einsele H, Kniemeyer O, Filler SG, Reichard U, Brakhage AA. Voltersen V, et al. mBio. 2018 Oct 2;9(5):e01557-18. doi: 10.1128/mBio.01557-18. mBio. 2018. PMID: 30279286 Free PMC article.

Novel Biological Functions of the NsdC Transcription Factor in Aspergillus fumigatus.

Alves de Castro P, Valero C, Chiaratto J, Colabardini AC, Pardeshi L, Pereira Silva L, Almeida F, Campos Rocha M, Nascimento Silva R, Malavazi I, Du W, Dyer PS, Brock M, Vieira Loures F, Wong KH, Goldman GH. Alves de Castro P, et al. mBio. 2021 Jan 5;12(1):e03102-20. doi: 10.1128/mBio.03102-20. mBio. 2021. PMID: 33402536 Free PMC article.

The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect.

Ries LNA, Rocha MC, de Castro PA, Silva-Rocha R, Silva RN, Freitas FZ, de Assis LJ, Bertolini MC, Malavazi I, Goldman GH. Ries LNA, et al. mBio. 2017 Jun 13;8(3):e00705-17. doi: 10.1128/mBio.00705-17. mBio. 2017. PMID: 28611248 Free PMC article.

Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity.

Thammahong A, Caffrey-Card AK, Dhingra S, Obar JJ, Cramer RA. Thammahong A, et al. mBio. 2017 Apr 25;8(2):e00056-17. doi: 10.1128/mBio.00056-17. mBio. 2017. PMID: 28442603 Free PMC article.