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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1994 1
1995 3
1996 7
1998 2
1999 3
2000 1
2001 3
2002 5
2003 5
2004 4
2005 2
2006 6
2007 8
2008 6
2009 7
2010 12
2011 8
2012 12
2013 17
2014 15
2015 9
2016 21
2017 15
2018 22
2019 23
2020 15
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208 results
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Page 1
Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors.
Dangaj D, Bruand M, Grimm AJ, Ronet C, Barras D, Duttagupta PA, Lanitis E, Duraiswamy J, Tanyi JL, Benencia F, Conejo-Garcia J, Ramay HR, Montone KT, Powell DJ Jr, Gimotty PA, Facciabene A, Jackson DG, Weber JS, Rodig SJ, Hodi SF, Kandalaft LE, Irving M, Zhang L, Foukas P, Rusakiewicz S, Delorenzi M, Coukos G. Dangaj D, et al. Among authors: Zhang L. Cancer Cell. 2019 Jun 10;35(6):885-900.e10. doi: 10.1016/j.ccell.2019.05.004. Cancer Cell. 2019. PMID: 31185212 Free PMC article.
We investigated the role of chemokines in regulating T cell accumulation in solid tumors. CCL5 and CXCL9 overexpression was associated with CD8(+) T cell infiltration in solid tumors. T cell infiltration required tumor cell-derived …
We investigated the role of chemokines in regulating T cell accumulation in solid tumors. CCL5 and CXCL9 overexpression was as …
Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy.
Tang XJ, Sun XY, Huang KM, Zhang L, Yang ZS, Zou DD, Wang B, Warnock GL, Dai LJ, Luo J. Tang XJ, et al. Among authors: Zhang L. Oncotarget. 2015 Dec 29;6(42):44179-90. doi: 10.18632/oncotarget.6175. Oncotarget. 2015. PMID: 26496034 Free PMC article. Review.
Chimeric antigen receptor (CAR)-based T-cell adoptive immunotherapy is a distinctively promising therapy for cancer. The engineering of CARs into T cells provides T cells with tumor-targeting capabilities and intensifies their cytotoxic activity throug …
Chimeric antigen receptor (CAR)-based T-cell adoptive immunotherapy is a distinctively promising therapy for cancer. The engin …
Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis.
Hong G, Zheng D, Zhang L, Ni R, Wang G, Fan GC, Lu Z, Peng T. Hong G, et al. Among authors: Zhang L. Free Radic Biol Med. 2018 Aug 1;123:125-137. doi: 10.1016/j.freeradbiomed.2018.05.073. Epub 2018 May 24. Free Radic Biol Med. 2018. PMID: 29803807 Free PMC article.
NR also prevented reactive oxygen species (ROS) production and apoptosis in endothelial cells induced by a conditioned-medium collected from LPS-treated macrophages. Furthermore, inhibition of SIRT1 by EX527 offset the negative effects of NR on HMGB1 release in macrophages …
NR also prevented reactive oxygen species (ROS) production and apoptosis in endothelial cells induced by a conditioned-medium collect …
Trazodone for the treatment of insomnia: a meta-analysis of randomized placebo-controlled trials.
Yi XY, Ni SF, Ghadami MR, Meng HQ, Chen MY, Kuang L, Zhang YQ, Zhang L, Zhou XY. Yi XY, et al. Among authors: Zhang YQ, Zhang L. Sleep Med. 2018 May;45:25-32. doi: 10.1016/j.sleep.2018.01.010. Epub 2018 Feb 7. Sleep Med. 2018. PMID: 29680424 Review.
Tolerability outcome was measured by the number of patients who discontinued for adverse events and acceptability outcome was measured by the number of patients who discontinued for all causes. ...Trazodone however, presented good tolerance in the short-term treatme
Tolerability outcome was measured by the number of patients who discontinued for adverse events and acceptability outcome was measure
Cellular immunotherapy for acute myeloid leukemia: How specific should it be?
Lee JB, Chen B, Vasic D, Law AD, Zhang L. Lee JB, et al. Among authors: Zhang L. Blood Rev. 2019 May;35:18-31. doi: 10.1016/j.blre.2019.02.001. Epub 2019 Feb 23. Blood Rev. 2019. PMID: 30826141 Review.
Significant improvements in the survival of patients with hematological cancers following hematopoietic stem cell transplantation provide evidence supporting the potency of immune cell-mediated anti-leukemic effects. Studies focusing on immune cell
Significant improvements in the survival of patients with hematological cancers following hematopoietic stem cell transplantation pro …
Resveratrol alleviates FFA and CCl4 induced apoptosis in HepG2 cells via restoring endoplasmic reticulum stress.
Li F, Yang Y, Yang L, Wang K, Zhang X, Zong Y, Ding Y, Wang C, Zhang L, Ji G. Li F, et al. Among authors: Zhang X, Zhang L. Oncotarget. 2017 Jul 4;8(27):43799-43809. doi: 10.18632/oncotarget.16460. Oncotarget. 2017. PMID: 28415630 Free PMC article.
Cell apoptosis often induces inflammation and injury in the liver, with endoplasmic reticulum (ER) stress as the most possible reason. ...Results showed that HepG2 cells co-cultured with FFA exhibited lipid infiltration and were susceptible to apoptosis upon
Cell apoptosis often induces inflammation and injury in the liver, with endoplasmic reticulum (ER) stress as the most possible
Allogeneic Human Double Negative T Cells as a Novel Immunotherapy for Acute Myeloid Leukemia and Its Underlying Mechanisms.
Lee J, Minden MD, Chen WC, Streck E, Chen B, Kang H, Arruda A, Ly D, Der SD, Kang S, Achita P, D'Souza C, Li Y, Childs RW, Dick JE, Zhang L. Lee J, et al. Among authors: Zhang L. Clin Cancer Res. 2018 Jan 15;24(2):370-382. doi: 10.1158/1078-0432.CCR-17-2228. Epub 2017 Oct 26. Clin Cancer Res. 2018. PMID: 29074605 Free article.
Purpose: To explore the potential of ex vivo expanded healthy donor-derived allogeneic CD4 and CD8 double-negative cells (DNT) as a novel cellular immunotherapy for leukemia patients.Experimental Design: Clinical-grade DNTs from peripheral blood of healthy donors were expa …
Purpose: To explore the potential of ex vivo expanded healthy donor-derived allogeneic CD4 and CD8 double-negative cells (DNT) as a n …
Afatinib as First-line Treatment of Older Patients With EGFR Mutation-Positive Non-Small-Cell Lung Cancer: Subgroup Analyses of the LUX-Lung 3, LUX-Lung 6, and LUX-Lung 7 Trials.
Wu YL, Sequist LV, Tan EH, Geater SL, Orlov S, Zhang L, Lee KH, Tsai CM, Kato T, Barrios CH, Schuler M, Hirsh V, Yamamoto N, O'Byrne K, Boyer M, Mok T, Peil B, Märten A, Chih-Hsin Yang J, Paz-Ares L, Park K. Wu YL, et al. Among authors: Zhang L. Clin Lung Cancer. 2018 Jul;19(4):e465-e479. doi: 10.1016/j.cllc.2018.03.009. Epub 2018 Mar 17. Clin Lung Cancer. 2018. PMID: 29653820 Free article. Clinical Trial.
BACKGROUND: Afatinib is approved in the US, Europe, and several other regions for first-line treatment for epidermal growth factor receptor mutation-positive (EGFRm(+)) non-small-cell lung cancer (NSCLC). ...CONCLUSIONS: Subgroup analyses of the LL3, LL6, and LL7 trials sh …
BACKGROUND: Afatinib is approved in the US, Europe, and several other regions for first-line treatment for epidermal growth factor receptor …
MiR-34b/c-5p and the neurokinin-1 receptor regulate breast cancer cell proliferation and apoptosis.
Zhang L, Wang L, Dong D, Wang Z, Ji W, Yu M, Zhang F, Niu R, Zhou Y. Zhang L, et al. Among authors: Zhang F. Cell Prolif. 2019 Jan;52(1):e12527. doi: 10.1111/cpr.12527. Epub 2018 Oct 17. Cell Prolif. 2019. PMID: 30334298 Free PMC article.
In addition, SP rescued the effects of miR-34b/c-5p overexpression or NK1R silencing on cell proliferation and apoptosis in vitro and in vivo assays. CONCLUSIONS: MiR-34b/c-5p and NK1R contribute to breast cancer cell proliferation and apoptosis and ar …
In addition, SP rescued the effects of miR-34b/c-5p overexpression or NK1R silencing on cell proliferation and apoptosis in vi …
Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.
Zhang C, Shi Z, Zhang L, Zhou Z, Zheng X, Liu G, Bu G, Fraser PE, Xu H, Zhang YW. Zhang C, et al. Among authors: Zhang L, Zhang YW. J Cell Sci. 2016 Mar 1;129(5):994-1002. doi: 10.1242/jcs.176792. Epub 2016 Jan 26. J Cell Sci. 2016. PMID: 26813789 Free PMC article.
Appoptosin overexpression causes overproduction of reactive oxygen species (ROS) and caspase-dependent apoptosis, whereas appoptosin downregulation abolishes β-amyloid-induced mitochondrial fragmentation and neuronal death during Alzheimer's disease. ...By contrast, co-exp …
Appoptosin overexpression causes overproduction of reactive oxygen species (ROS) and caspase-dependent apoptosis, whereas appoptosin …
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