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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1986 1
1993 1
1994 1
1995 2
1996 3
1997 4
1998 2
1999 5
2000 2
2001 3
2002 6
2003 5
2004 6
2005 3
2006 1
2007 9
2008 9
2009 5
2010 8
2011 6
2012 4
2013 5
2014 6
2015 8
2016 9
2017 2
2018 4
2019 4
2020 8
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122 results
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Page 1
Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension.
Prins KW, Tian L, Wu D, Thenappan T, Metzger JM, Archer SL. Prins KW, et al. Among authors: metzger jm. J Am Heart Assoc. 2017 May 31;6(6):e006195. doi: 10.1161/JAHA.117.006195. J Am Heart Assoc. 2017. PMID: 28566298 Free PMC article.
METHODS AND RESULTS: Immunoblots, confocal microscopy, echocardiography, cardiac catheterization, and treadmill testing were used to examine colchicine's (0.5 mg/kg 3 times/week) effects on pulmonary hemodynamics, RV function, and functional capacity. ...
METHODS AND RESULTS: Immunoblots, confocal microscopy, echocardiography, cardiac catheterization, and treadmill testing were used to examine …
Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury.
Houang EM, Bartos J, Hackel BJ, Lodge TP, Yannopoulos D, Bates FS, Metzger JM. Houang EM, et al. Among authors: metzger jm. JACC Basic Transl Sci. 2019 Apr 29;4(2):275-287. doi: 10.1016/j.jacbts.2019.01.009. eCollection 2019 Apr. JACC Basic Transl Sci. 2019. PMID: 31061929 Free PMC article. Review.
Collectively, muscle membrane instability contributes significantly to morbidity and mortality in prominent acquired and inherited heart diseases. In this context, chemical-based muscle membrane stabilizers provide a novel therapeutic approach for a myriad of heart
Collectively, muscle membrane instability contributes significantly to morbidity and mortality in prominent acquired and inherited heart
A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.
Davis J, Davis LC, Correll RN, Makarewich CA, Schwanekamp JA, Moussavi-Harami F, Wang D, York AJ, Wu H, Houser SR, Seidman CE, Seidman JG, Regnier M, Metzger JM, Wu JC, Molkentin JD. Davis J, et al. Among authors: metzger jm. Cell. 2016 May 19;165(5):1147-1159. doi: 10.1016/j.cell.2016.04.002. Epub 2016 Apr 21. Cell. 2016. PMID: 27114035 Free PMC article.
The heart either hypertrophies or dilates in response to familial mutations in genes encoding sarcomeric proteins, which are responsible for contraction and pumping. ...By generating a series of cardiac-specific mouse models that permit the systematic tuning of sarcomeric …
The heart either hypertrophies or dilates in response to familial mutations in genes encoding sarcomeric proteins, which are responsi …
Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes.
Bedada FB, Wheelwright M, Metzger JM. Bedada FB, et al. Among authors: metzger jm. Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1829-38. doi: 10.1016/j.bbamcr.2015.11.005. Epub 2015 Nov 11. Biochim Biophys Acta. 2016. PMID: 26578113 Free PMC article. Review.
Human heart failure due to myocardial infarction is a major health concern. The paucity of organs for transplantation limits curative approaches for the diseased and failing adult heart. ...This article is part of a Special Issue entitled: Cardiomyocyte Biology: Int …
Human heart failure due to myocardial infarction is a major health concern. The paucity of organs for transplantation limits curative …
Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency mediated chronically increased cardiac Ca2+ cycling in vivo.
Law ML, Prins KW, Olander ME, Metzger JM. Law ML, et al. Among authors: metzger jm. Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1544-H1552. doi: 10.1152/ajpheart.00341.2018. Epub 2018 Aug 17. Am J Physiol Heart Circ Physiol. 2018. PMID: 30118340 Free PMC article.
Furthermore, Evans blue dye uptake was increased in DKO hearts compared with control, mdx, and PLNKO hearts, demonstrating increased membrane damage, which subsequently led to increased fibrosis in the DKO myocardium in vivo. ...Listen to this article's corre …
Furthermore, Evans blue dye uptake was increased in DKO hearts compared with control, mdx, and PLNKO hearts, demonstrating inc …
Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers.
Houang EM, Sham YY, Bates FS, Metzger JM. Houang EM, et al. Among authors: metzger jm. Skelet Muscle. 2018 Oct 10;8(1):31. doi: 10.1186/s13395-018-0177-7. Skelet Muscle. 2018. PMID: 30305165 Free PMC article. Review.
Dysregulation of Calcium Handling in Duchenne Muscular Dystrophy-Associated Dilated Cardiomyopathy: Mechanisms and Experimental Therapeutic Strategies.
Law ML, Cohen H, Martin AA, Angulski ABB, Metzger JM. Law ML, et al. Among authors: metzger jm. J Clin Med. 2020 Feb 14;9(2):520. doi: 10.3390/jcm9020520. J Clin Med. 2020. PMID: 32075145 Free PMC article. Review.
Investigation of human iPSC-derived cardiac myocyte functional maturation by single cell traction force microscopy.
Wheelwright M, Win Z, Mikkila JL, Amen KY, Alford PW, Metzger JM. Wheelwright M, et al. Among authors: metzger jm. PLoS One. 2018 Apr 4;13(4):e0194909. doi: 10.1371/journal.pone.0194909. eCollection 2018. PLoS One. 2018. PMID: 29617427 Free PMC article.
Gene Transfer of Calcium-Binding Proteins into Adult Cardiac Myocytes.
Thompson BR, Cohen H, Angulski ABB, Metzger JM. Thompson BR, et al. Among authors: metzger jm. Methods Mol Biol. 2019;1929:187-205. doi: 10.1007/978-1-4939-9030-6_12. Methods Mol Biol. 2019. PMID: 30710274 Free PMC article.
Heart failure is the leading cause of combined morbidity and mortality in the USA with 50% of cases being diastolic heart failure. ...These protocols have been used extensively to optimize parvalbumin function as a potential therapeutic for failing heart musc
Heart failure is the leading cause of combined morbidity and mortality in the USA with 50% of cases being diastolic heart fail
Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration.
Metzger JM, Matsoff HN, Zinnen AD, Fleddermann RA, Bondarenko V, Simmons HA, Mejia A, Moore CF, Emborg ME. Metzger JM, et al. PLoS One. 2020 Jan 7;15(1):e0226999. doi: 10.1371/journal.pone.0226999. eCollection 2020. PLoS One. 2020. PMID: 31910209 Free PMC article.
Cardiac dysautonomia is a common nonmotor symptom of Parkinson's disease (PD) associated with loss of sympathetic innervation to the heart and decreased plasma catecholamines. ...In the heart, 6-OHDA-treated animals showed a significant loss of sympathetic ne …
Cardiac dysautonomia is a common nonmotor symptom of Parkinson's disease (PD) associated with loss of sympathetic innervation to the …
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