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1996 1
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1998 3
1999 2
2000 3
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2003 4
2004 2
2005 2
2006 3
2007 2
2009 2
2010 2
2011 3
2012 3
2013 2
2014 1
2015 2
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2017 2
2018 1
2019 3
2020 6
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Page 1
Dissociation of systemic and mucosal autoimmunity in cystic fibrosis.
Theprungsirikul J, Skopelja-Gardner S, Meagher RE, Clancy JP, Zemanick ET, Ashare A, Rigby WFC. Theprungsirikul J, et al. J Cyst Fibros. 2020 Mar;19(2):196-202. doi: 10.1016/j.jcf.2019.06.006. Epub 2019 Jun 28. J Cyst Fibros. 2020. PMID: 31262645
BACKGROUND: Pseudomonas aeruginosa accounts for ~80% of cystic fibrosis (CF) airway infection. It shows a remarkable correlation with presence of autoantibody to bactericidal/permeability-increasing protein (BPI), which is not understood. ...Thus, BAL IgA ant …
BACKGROUND: Pseudomonas aeruginosa accounts for ~80% of cystic fibrosis (CF) airway infection. It shows a remarkable correlati …
Autoantibody response to BPI predict disease severity and outcome in cystic fibrosis.
Carlsson M, Eriksson L, Pressler T, Kornfält R, Mared L, Meyer P, Wiik A, Wieslander J, Segelmark M. Carlsson M, et al. J Cyst Fibros. 2007 May;6(3):228-33. doi: 10.1016/j.jcf.2006.10.005. Epub 2006 Dec 12. J Cyst Fibros. 2007. PMID: 17166780 Free article.
BACKGROUND: Autoantibodies against bactericidal permeability increasing protein (BPI-ANCA) are frequently present in cystic fibrosis patients and have been reported to be associated to colonization with Pseudomonas (P) aeruginosa and lung damage. ...RESULTS: …
BACKGROUND: Autoantibodies against bactericidal permeability increasing protein (BPI-ANCA) are frequently present in cystic
BPI-ANCA of pediatric cystic fibrosis patients can impair BPI-mediated killing of E. coli DH5alpha in vitro.
Schultz H, Schinke S, Mosler K, Herlyn K, Schuster A, Gross WL. Schultz H, et al. Pediatr Pulmonol. 2004 Feb;37(2):158-64. doi: 10.1002/ppul.10416. Pediatr Pulmonol. 2004. PMID: 14730661
Gram-negative bacterial lung infections and chronic bacterial colonization are major threats for pediatric cystic fibrosis (CF) patients. ...Moreover, epitope mapping over the whole BPI sequence revealed that more patients' BPI-ANCA recognize the amino …
Gram-negative bacterial lung infections and chronic bacterial colonization are major threats for pediatric cystic fibrosis (CF …
Prevalence and clinical significance of auto-antibodies in adults with cystic fibrosis.
Lachenal F, Nkana K, Nove-Josserand R, Fabien N, Durieu I. Lachenal F, et al. Eur Respir J. 2009 Nov;34(5):1079-85. doi: 10.1183/09031936.00006009. Epub 2009 May 14. Eur Respir J. 2009. PMID: 19443536 Free article.
The aim of this study was to determine the prevalence of different auto-antibodies in adult, French cystic fibrosis (CF) patients and to look for a correlation between autoimmunity, patient characteristics and survival. ...Clinical, biological and bacteriological ch …
The aim of this study was to determine the prevalence of different auto-antibodies in adult, French cystic fibrosis (CF) patie …
Increased platelet activation occurs in cystic fibrosis patients and correlates to clinical status.
Lindberg U, Svensson L, Hellmark T, Segelmark M, Shannon O. Lindberg U, et al. Thromb Res. 2018 Feb;162:32-37. doi: 10.1016/j.thromres.2017.12.012. Epub 2017 Dec 19. Thromb Res. 2018. PMID: 29274562
Cystic fibrosis (CF) is an inflammatory lung disease. Platelets have an emerging role in inflammation, however previous studies of platelet activation in CF have generated conflicting results. ...In the CF group, platelet aggregation correlates with levels of anti-n
Cystic fibrosis (CF) is an inflammatory lung disease. Platelets have an emerging role in inflammation, however previous studie
Anti-neutrophil cytoplasmatic antibodies and lung disease in cystic fibrosis.
Dorlöchter L, Carlsson M, Olafsdottir EJ, Røksund OD, Rosendahl K, Fluge G. Dorlöchter L, et al. J Cyst Fibros. 2004 Aug;3(3):179-83. doi: 10.1016/j.jcf.2004.04.005. J Cyst Fibros. 2004. PMID: 15463905 Free article.
Anti-neutrophil cytoplasmatic antibodies (ANCA) directed against BPI have been detected in up to 91% in patients with cystic fibrosis (CF). ...Serum samples were analysed by direct binding enzyme-linked immunosorbent assay for BPI-ANCA. RESULTS: The pr …
Anti-neutrophil cytoplasmatic antibodies (ANCA) directed against BPI have been detected in up to 91% in patients with cystic
Prevalence of Bactericidal/Permeability-Increasing Protein Autoantibodies in Cystic Fibrosis Patients: Systematic Review and Meta-Analysis.
Iwuji K, Larumbe-Zabala E, Bijlani S, Nugent K, Kanu A, Manning E, Solis X. Iwuji K, et al. Pediatr Allergy Immunol Pulmonol. 2019 Jun 1;32(2):45-51. doi: 10.1089/ped.2018.0970. Epub 2019 Jun 17. Pediatr Allergy Immunol Pulmonol. 2019. PMID: 31508255 Free PMC article. Review.
Background: There have been varying reports on the prevalence of antineutrophil cytoplasmic antibodies with bactericidal/permeability-increasing protein (BPI-ANCA) specificity in cystic fibrosis (CF) patients. ...We also searched the Journal of Cystic
Background: There have been varying reports on the prevalence of antineutrophil cytoplasmic antibodies with bactericidal/permeability-increa …
Pseudomonas aeruginosa in cystic fibrosis: pyocyanin negative strains are associated with BPI-ANCA and progressive lung disease.
Carlsson M, Shukla S, Petersson AC, Segelmark M, Hellmark T. Carlsson M, et al. J Cyst Fibros. 2011 Jul;10(4):265-71. doi: 10.1016/j.jcf.2011.03.004. Epub 2011 Apr 3. J Cyst Fibros. 2011. PMID: 21463973 Free article.
The clinical consequence of chronic Pseudomonas aeruginosa colonization in cystic fibrosis (CF) varies between individuals for unknown reasons. ...We compared isolates of P. aeruginosa from BPI-ANCA positive CF patients who have deteriorating lung disease wit …
The clinical consequence of chronic Pseudomonas aeruginosa colonization in cystic fibrosis (CF) varies between individuals for …
Pseudomonas-induced lung damage in cystic fibrosis correlates to bactericidal-permeability increasing protein (BPI)-autoantibodies.
Carlsson M, Eriksson L, Erwander I, Wieslander J, Segelmark M. Carlsson M, et al. Clin Exp Rheumatol. 2003 Nov-Dec;21(6 Suppl 32):S95-100. Clin Exp Rheumatol. 2003. PMID: 14740434
OBJECTIVE: Lung damage is the most common cause of death in cystic fibrosis (CF). It is induced by bacterial colonization and inflammatory activity perpetuates its course. Autoantibodies directed against BPI (bactericidal permeability increasing protein), cal …
OBJECTIVE: Lung damage is the most common cause of death in cystic fibrosis (CF). It is induced by bacterial colonization and …
Expression and antimicrobial function of bactericidal permeability-increasing protein in cystic fibrosis patients.
Aichele D, Schnare M, Saake M, Röllinghoff M, Gessner A. Aichele D, et al. Infect Immun. 2006 Aug;74(8):4708-14. doi: 10.1128/IAI.02066-05. Infect Immun. 2006. PMID: 16861658 Free PMC article.
In cystic fibrosis (CF), the condition limiting the prognosis of affected children is the chronic obstructive lung disease accompanied by chronic and persistent infection with mostly mucoid strains of Pseudomonas aeruginosa. The majority of CF patients have antineut …
In cystic fibrosis (CF), the condition limiting the prognosis of affected children is the chronic obstructive lung disease acc …
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