Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 3
2000 15
2001 14
2002 16
2003 24
2004 21
2005 16
2006 32
2007 29
2008 29
2009 28
2010 34
2011 29
2012 38
2013 60
2014 51
2015 48
2016 52
2017 51
2018 52
2019 49
2020 42
Text availability
Article attribute
Article type
Publication date

Search Results

642 results
Results by year
Filters applied: . Clear all
Page 1
Progressive Familial Intrahepatic Cholestasis.
Bull LN, Thompson RJ. Bull LN, et al. Clin Liver Dis. 2018 Nov;22(4):657-669. doi: 10.1016/j.cld.2018.06.003. Epub 2018 Aug 3. Clin Liver Dis. 2018. PMID: 30266155 Free article. Review.
Genetic cholestasis has been dissected through genetic investigation. The major PFIC genes are now described. ATP8B1 encodes FIC1, ABCB11 encodes BSEP, ABCB4 encodes MDR3, TJP2 encodes TJP2, NR1H4 encodes FXR, and MYO5B encodes MYO5B. ...
Genetic cholestasis has been dissected through genetic investigation. The major PFIC genes are now described. ATP8B1 encodes FIC1, …
Jaundice revisited: recent advances in the diagnosis and treatment of inherited cholestatic liver diseases.
Chen HL, Wu SH, Hsu SH, Liou BY, Chen HL, Chang MH. Chen HL, et al. J Biomed Sci. 2018 Oct 26;25(1):75. doi: 10.1186/s12929-018-0475-8. J Biomed Sci. 2018. PMID: 30367658 Free PMC article. Review.
The first three types of PFICs identified (PFIC1, PFIC2, and PFIC3) represent defects in FIC1 (ATP8B1), BSEP (ABCB11), or MDR3 (ABCB4). ...New drug development based on gene-specific treatments, such as apical sodium-dependent bile acid transporter (ASBT) inhibitor, …
The first three types of PFICs identified (PFIC1, PFIC2, and PFIC3) represent defects in FIC1 (ATP8B1), BSEP (ABCB11), or MDR3 …
Cryptogenic cholestasis in young and adults: ATP8B1, ABCB11, ABCB4, and TJP2 gene variants analysis by high-throughput sequencing.
Vitale G, Gitto S, Raimondi F, Mattiaccio A, Mantovani V, Vukotic R, D'Errico A, Seri M, Russell RB, Andreone P. Vitale G, et al. J Gastroenterol. 2018 Aug;53(8):945-958. doi: 10.1007/s00535-017-1423-1. Epub 2017 Dec 13. J Gastroenterol. 2018. PMID: 29238877
BACKGROUND: Mutations in ATP-transporters ATPB81, ABCB11, and ABCB4 are responsible for progressive familial intrahepatic cholestasis (PFIC) 1, 2 and 3, and recently the gene for tight junction protein-2 (TJP2) has been linked to PFIC4. ...RESULTS: Of 108 patients, …
BACKGROUND: Mutations in ATP-transporters ATPB81, ABCB11, and ABCB4 are responsible for progressive familial intrahepatic cholesta
Drug-induced Cholestasis: Mechanisms, Models, and Markers.
Chatterjee S, Annaert P. Chatterjee S, et al. Curr Drug Metab. 2018;19(10):808-818. doi: 10.2174/1389200219666180427165035. Curr Drug Metab. 2018. PMID: 29708070 Review.
Intrahepatic accumulation of Bile Acids (BAs) represents a characteristic phenomenon associated with drug-induced cholestasis. ...Increased insight into susceptibility factors in addition to Bile Salt Export Pump (BSEP) inhibition, biomarkers and involvement of immu …
Intrahepatic accumulation of Bile Acids (BAs) represents a characteristic phenomenon associated with drug-induced cholestasis. ...Inc …
New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications.
Sticova E, Jirsa M, Pawłowska J. Sticova E, et al. Can J Gastroenterol Hepatol. 2018 Jul 26;2018:2313675. doi: 10.1155/2018/2313675. eCollection 2018. Can J Gastroenterol Hepatol. 2018. PMID: 30148122 Free PMC article. Review.
Thus far, five representatives of PFIC (named PFIC1-5) caused by pathogenic mutations present in both alleles of ATP8B1, ABCB11, ABCB4, TJP2, and NR1H4 have been described. In addition to familial intrahepatic cholestasis, partial defects in ATP8B1, ABCB11, a …
Thus far, five representatives of PFIC (named PFIC1-5) caused by pathogenic mutations present in both alleles of ATP8B1, ABCB11, ABCB …
Systematic review of progressive familial intrahepatic cholestasis.
Baker A, Kerkar N, Todorova L, Kamath BM, Houwen RHJ. Baker A, et al. Clin Res Hepatol Gastroenterol. 2019 Feb;43(1):20-36. doi: 10.1016/j.clinre.2018.07.010. Epub 2018 Sep 17. Clin Res Hepatol Gastroenterol. 2019. PMID: 30236549 Free article.
BACKGROUND AND AIMS: Progressive familial intrahepatic cholestasis (PFIC) is a heterogeneous group of rare genetic disorders associated with bile acid secretion or transport defects. ...Incidence of intrahepatic cholestasis, including but not limited to PFIC, was 1/ …
BACKGROUND AND AIMS: Progressive familial intrahepatic cholestasis (PFIC) is a heterogeneous group of rare genetic disorders associat …
Familial intrahepatic cholestasis: New and wide perspectives.
Vitale G, Gitto S, Vukotic R, Raimondi F, Andreone P. Vitale G, et al. Dig Liver Dis. 2019 Jul;51(7):922-933. doi: 10.1016/j.dld.2019.04.013. Epub 2019 May 16. Dig Liver Dis. 2019. PMID: 31105019 Review.
PFIC2 includes ABCB11 gene, encoding for protein functioning as bile salt export pump. PFIC3 is due to mutations of ABCB4 gene responsible for the synthesis of class III multidrug resistance P-glycoprotein flippase. ...Benign Intrahepatic Cholestasis, Intrahepatic …
PFIC2 includes ABCB11 gene, encoding for protein functioning as bile salt export pump. PFIC3 is due to mutations of ABCB4 gene respon …
Up-regulation of BSEP and MRP2 by Calculus Bovis administration in 17α-ethynylestradiol-induced cholestasis: Involvement of PI3K/Akt signaling pathway.
Wu T, Zhang Q, Li J, Chen H, Wu J, Song H. Wu T, et al. J Ethnopharmacol. 2016 Aug 22;190:22-32. doi: 10.1016/j.jep.2016.05.056. Epub 2016 May 27. J Ethnopharmacol. 2016. PMID: 27237619
AIM OF THE STUDY: This study aimed to investigate the choleretic potential and molecular responses in rats to Calculus Bovis (CB) administration after 17α-ethynylestradiol (EE)-induced cholestasis. ...Decreased expression of BSEP and MRP2 caused by EE were also prev …
AIM OF THE STUDY: This study aimed to investigate the choleretic potential and molecular responses in rats to Calculus Bovis (CB) administra …
Expanding etiology of progressive familial intrahepatic cholestasis.
Henkel SA, Squires JH, Ayers M, Ganoza A, Mckiernan P, Squires JE. Henkel SA, et al. World J Hepatol. 2019 May 27;11(5):450-463. doi: 10.4254/wjh.v11.i5.450. World J Hepatol. 2019. PMID: 31183005 Free PMC article.
BACKGROUND: Progressive familial intrahepatic cholestasis (PFIC) refers to a disparate group of autosomal recessive disorders that are linked by the inability to appropriately form and excrete bile from hepatocytes, resulting in a hepatocellular form of cholestasis. …
BACKGROUND: Progressive familial intrahepatic cholestasis (PFIC) refers to a disparate group of autosomal recessive disorders that ar …
Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited.
Paumgartner G, Beuers U. Paumgartner G, et al. Hepatology. 2002 Sep;36(3):525-31. doi: 10.1053/jhep.2002.36088. Hepatology. 2002. PMID: 12198643 Review.
., bile salt export pump, BSEP, and conjugate export pump, MRP2) into the canalicular membrane of the hepatocyte and, possibly, activation of inserted carriers; (3) protection of hepatocytes against bile acid-induced apoptosis, involving inhibition of mitochondrial membran …
., bile salt export pump, BSEP, and conjugate export pump, MRP2) into the canalicular membrane of the hepatocyte and, possibly, activ …
642 results
Jump to page
Feedback