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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1994 1
1995 1
1997 1
1998 3
1999 2
2000 3
2001 7
2002 6
2003 16
2004 12
2005 14
2006 13
2007 20
2008 10
2009 10
2010 13
2011 12
2012 13
2013 7
2014 9
2015 4
2016 10
2017 3
2018 3
2019 4
2020 1
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181 results
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Page 1
Inflammatory bowel disease: pathogenesis.
Zhang YZ, Li YY. Zhang YZ, et al. World J Gastroenterol. 2014 Jan 7;20(1):91-9. doi: 10.3748/wjg.v20.i1.91. World J Gastroenterol. 2014. PMID: 24415861 Free PMC article. Review.
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is characterized by chronic relapsing intestinal inflammation. ...The latest internationally collaborative studies have ascertained 163 susceptibility gene loci …
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is characterized by chronic relapsi …
Immunopathogenesis of IBD: current state of the art.
de Souza HS, Fiocchi C. de Souza HS, et al. Nat Rev Gastroenterol Hepatol. 2016 Jan;13(1):13-27. doi: 10.1038/nrgastro.2015.186. Epub 2015 Dec 2. Nat Rev Gastroenterol Hepatol. 2016. PMID: 26627550 Review.
IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main clinical entities: Crohn's disease and ulcerative colitis. ...Both Crohn's disease and ulcerative colitis are associated with multiple pathogenic factors includ …
IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main clinical entities: Crohn's disease
The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network.
Friedrichs F, Henckaerts L, Vermeire S, Kucharzik T, Seehafer T, Möller-Krull M, Bornberg-Bauer E, Stoll M, Weiner J 3rd. Friedrichs F, et al. J Mol Med (Berl). 2008 Apr;86(4):423-32. doi: 10.1007/s00109-008-0307-5. Epub 2008 Mar 12. J Mol Med (Berl). 2008. PMID: 18335190
Discs large homolog 5 (DLG5), a member of the membrane-associated guanylate kinase (MAGUK) family of scaffolding proteins, has been associated with Crohn's disease (CD), but its role in the pathogenesis of this inflammatory bowel disease is disputed. ...DLG5 …
Discs large homolog 5 (DLG5), a member of the membrane-associated guanylate kinase (MAGUK) family of scaffolding proteins, has been associat …
Association between MDR1 gene polymorphisms and the risk of Crohn's disease in a cohort of Algerian pediatric patients.
Bouzidi A, Mesbah-Amroun H, Boukercha A, Benhassine F, Belboueb R, Berkouk K, Messadi W, Touil-Boukoffa C. Bouzidi A, et al. Pediatr Res. 2016 Dec;80(6):837-843. doi: 10.1038/pr.2016.163. Epub 2016 Sep 7. Pediatr Res. 2016. PMID: 27603561
BACKGROUND: The multi-drug resistance gene (MDR1) has raised increasing interest as a susceptibility gene for Crohn's disease (CD). ...CONCLUSION: Our data suggest that the C1236T and G2677A/T SNPs in the MDR1 gene are associated with CD …
BACKGROUND: The multi-drug resistance gene (MDR1) has raised increasing interest as a susceptibility gene for Crohn
Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.
Simmons JD, Mullighan C, Welsh KI, Jewell DP. Simmons JD, et al. Gut. 2000 Aug;47(2):211-4. doi: 10.1136/gut.47.2.211. Gut. 2000. PMID: 10896912 Free PMC article.
BACKGROUND: The vitamin D receptor (VDR) gene represents a strong positional candidate susceptibility gene for inflammatory bowel disease (IBD). ...CONCLUSION: This study provides preliminary evidence for a genetic association between Crohn's …
BACKGROUND: The vitamin D receptor (VDR) gene represents a strong positional candidate susceptibility gene for inflamma …
Non-association of Crohn's disease with NOD2 gene variants in Moroccan patients.
Hama I, Ratbi I, Reggoug S, Elkerch F, Kharrasse G, Errabih I, Ouazzani H, Sefiani A. Hama I, et al. Gene. 2012 May 10;499(1):121-3. doi: 10.1016/j.gene.2011.12.045. Epub 2012 Jan 14. Gene. 2012. PMID: 22266421
However, the major susceptibility gene for Crohn's disease is NOD2, located on proximal 16q, which is involved in the innate immune response. ...There is no data about the frequency of these allelic variants in Moroccan patients with Crohn's …
However, the major susceptibility gene for Crohn's disease is NOD2, located on proximal 16q, which is involved i …
IRGM variants and susceptibility to inflammatory bowel disease in the German population.
Glas J, Seiderer J, Bues S, Stallhofer J, Fries C, Olszak T, Tsekeri E, Wetzke M, Beigel F, Steib C, Friedrich M, Göke B, Diegelmann J, Czamara D, Brand S. Glas J, et al. PLoS One. 2013;8(1):e54338. doi: 10.1371/journal.pone.0054338. Epub 2013 Jan 24. PLoS One. 2013. PMID: 23365659 Free PMC article.
BACKGROUND & AIMS: Genome-wide association studies identified the autophagy gene IRGM to be strongly associated with Crohn's disease (CD) but its impact in ulcerative colitis (UC), its phenotypic effects and potential epistatic interactions with other IBD …
BACKGROUND & AIMS: Genome-wide association studies identified the autophagy gene IRGM to be strongly associated with Crohn
HLA-linked susceptibility and resistance genes in Crohn's disease.
Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. Nakajima A, et al. Gastroenterology. 1995 Nov;109(5):1462-7. doi: 10.1016/0016-5085(95)90631-2. Gastroenterology. 1995. PMID: 7557126
BACKGROUND & AIMS: Previous studies have shown a positive association of HLA-DR4-DQ4 with Crohn's disease in the Japanese population, but the association between Crohn's disease and HLA genes has yet to be fully elucidated. ...CONCLUSIONS: In Cr
BACKGROUND & AIMS: Previous studies have shown a positive association of HLA-DR4-DQ4 with Crohn's disease in the Japanese …
Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn's disease colon.
Berrebi D, Maudinas R, Hugot JP, Chamaillard M, Chareyre F, De Lagausie P, Yang C, Desreumaux P, Giovannini M, Cézard JP, Zouali H, Emilie D, Peuchmaur M. Berrebi D, et al. Gut. 2003 Jun;52(6):840-6. doi: 10.1136/gut.52.6.840. Gut. 2003. PMID: 12740340 Free PMC article.
CARD15 is the first susceptibility gene implicated in the predisposition to Crohn's disease and is known to be expressed only in monocytes. ...CONCLUSIONS: We have demonstrated that colonic involvement in active Crohn's disease is associa …
CARD15 is the first susceptibility gene implicated in the predisposition to Crohn's disease and is known to be e …
A Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn's Disease in Japanese Individuals.
Kakuta Y, Kawai Y, Naito T, Hirano A, Umeno J, Fuyuno Y, Liu Z, Li D, Nakano T, Izumiyama Y, Ichikawa R, Okamoto D, Nagai H, Matsumoto S, Yamamoto K, Yokoyama N, Chiba H, Shimoyama Y, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Negoro K, Yasuda J, Esaki M, Tokunaga K, Nakamura M, Matsumoto T, McGovern DPB, Nagasaki M, Kinouchi Y, Shimosegawa T, Masamune A. Kakuta Y, et al. J Crohns Colitis. 2019 Apr 26;13(5):648-658. doi: 10.1093/ecco-jcc/jjy197. J Crohns Colitis. 2019. PMID: 30500874 Free PMC article.
BACKGROUND AND AIMS: Genome-wide association studies [GWASs] of European populations have identified numerous susceptibility loci for Crohn's disease [CD]. ...CONCLUSIONS: RAP1A is a novel susceptibility locus for CD in the Japanese population....
BACKGROUND AND AIMS: Genome-wide association studies [GWASs] of European populations have identified numerous susceptibility loci for …
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