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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1971 1
1982 1
1993 1
1994 8
1995 49
1996 115
1997 229
1998 321
1999 432
2000 479
2001 513
2002 467
2003 479
2004 435
2005 468
2006 409
2007 369
2008 365
2009 343
2010 343
2011 326
2012 324
2013 383
2014 347
2015 318
2016 287
2017 267
2018 280
2019 233
2020 194
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8,118 results
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Page 1
Dual Role of Fas/FasL-Mediated Signal in Peripheral Immune Tolerance.
Yamada A, Arakaki R, Saito M, Kudo Y, Ishimaru N. Yamada A, et al. Front Immunol. 2017 Apr 5;8:403. doi: 10.3389/fimmu.2017.00403. eCollection 2017. Front Immunol. 2017. PMID: 28424702 Free PMC article. Review.
The precise pathways and unique functions associated with Fas/FasL-mediated signaling in the immune system are known. The dual character of Fas/FasL-mediated immune regulation that induces beneficial or harmful effects is associated with the onset or development of …
The precise pathways and unique functions associated with Fas/FasL-mediated signaling in the immune system are known. The dual charac …
TRAIL and FasL Functions in Cancer and Autoimmune Diseases: Towards an Increasing Complexity.
Rossin A, Miloro G, Hueber AO. Rossin A, et al. Cancers (Basel). 2019 May 8;11(5):639. doi: 10.3390/cancers11050639. Cancers (Basel). 2019. PMID: 31072029 Free PMC article. Review.
Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL/TNFSF10) and Fas Ligand (FasL/TNFSF6), two major cytokines of the TNF (Tumor Necrosis Factor) superfamily, exert their main functions from the immune system compartment. ...The discovery that they are mu …
Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL/TNFSF10) and Fas Ligand (FasL/TNFSF6), two major cytokines of t …
Soluble FAS ligand is not required for pancreatic islet inflammation or beta-cell destruction in non-obese diabetic mice.
Trivedi PM, Fynch S, Kennedy LM, Chee J, Krishnamurthy B, O'Reilly LA, Strasser A, Kay TWH, Thomas HE. Trivedi PM, et al. Cell Death Discov. 2019 Sep 23;5:136. doi: 10.1038/s41420-019-0217-z. eCollection 2019. Cell Death Discov. 2019. PMID: 31552143 Free PMC article.
However, blocking FASL pharmacologically was shown to protect NOD mice from diabetes, indicating that FASL may have some role. ...We generated NOD mice deficient in soluble FASL, while maintaining expression of membrane-bound FASL due to a mutation in …
However, blocking FASL pharmacologically was shown to protect NOD mice from diabetes, indicating that FASL may have some role. …
RETRACTED ARTICLE: 67-kDa laminin receptor induces FasL expression and FasL-mediated apoptosis through the activation of c-Myc and the subsequent activation of the FasL promoter in human cholangiocarcinoma cells.
[No authors listed] [No authors listed] J Cancer Res Clin Oncol. 2011 Mar;137(3):391. doi: 10.1007/s00432-010-0804-0. Epub 2010 Feb 13. J Cancer Res Clin Oncol. 2011. PMID: 20155283 No abstract available.
Dysregulation of the Fas/FasL system in mononuclear cells recovered from peritoneal fluid of women with endometriosis.
Sturlese E, Salmeri FM, Retto G, Pizzo A, De Dominici R, Ardita FV, Borrielli I, Licata N, Laganà AS, Sofo V. Sturlese E, et al. J Reprod Immunol. 2011 Dec;92(1-2):74-81. doi: 10.1016/j.jri.2011.08.005. Epub 2011 Oct 5. J Reprod Immunol. 2011. PMID: 21978769
In contrast to FasL protein, FasL mRNA was overexpressed throughout the course of the disease. sFasL values were high and increased as the disease worsened. Our results showed a non-linear ratio between FasL mRNA and FasL protein levels. Abnormally ele …
In contrast to FasL protein, FasL mRNA was overexpressed throughout the course of the disease. sFasL values were high and incr …
Active transcription of the human FASL/CD95L/TNFSF6 promoter region in T lymphocytes involves chromatin remodeling: role of DNA methylation and protein acetylation suggest distinct mechanisms of transcriptional repression.
Castellano R, Vire B, Pion M, Quivy V, Olive D, Hirsch I, Van Lint C, Collette Y. Castellano R, et al. J Biol Chem. 2006 May 26;281(21):14719-28. doi: 10.1074/jbc.M602373200. Epub 2006 Apr 4. J Biol Chem. 2006. PMID: 16595663 Free article.
Fas ligand (FasL/CD95L/TNFSF6), a member of the tumor necrosis factor family, initiates apoptosis in lymphoid and nonlymphoid tissues by binding to its receptor Fas (CD95/TNFRSF6). ...HSS1 chromatin remodeling preceded detectable TNFSF6 mRNA accumulation and …
Fas ligand (FasL/CD95L/TNFSF6), a member of the tumor necrosis factor family, initiates apoptosis in lymphoid and nonlymphoid …
FasL Modulates Expression of Mmp2 in Osteoblasts.
Svandova E, Vesela B, Lesot H, Sadoine J, Poliard A, Matalova E. Svandova E, et al. Front Physiol. 2018 Sep 19;9:1314. doi: 10.3389/fphys.2018.01314. eCollection 2018. Front Physiol. 2018. PMID: 30283358 Free PMC article.
This is supported by non-apoptotic appearance of FasL during osteogenesis and by significant bone alterations unrelated to apoptosis in FasL deficient (gld) mice. ...To examine the possibility of this novel FasL-Mmp2 relationship, intramembranous bone-derived …
This is supported by non-apoptotic appearance of FasL during osteogenesis and by significant bone alterations unrelated to apoptosis …
Ionizing radiation alters Fas antigen ligand at the cell surface and on exfoliated plasma membrane-derived vesicles: implications for apoptosis and intercellular signaling.
Albanese J, Dainiak N. Albanese J, et al. Radiat Res. 2000 Jan;153(1):49-61. doi: 10.1667/0033-7587(2000)153[0049:irafal]2.0.co;2. Radiat Res. 2000. PMID: 10630977
Ionizing radiation modulates the expression of many plasma membrane-bound growth regulators, including the "death" ligand, TNFSF6 (formerly known as FasL, CD95L). Here we report that ionizing radiation induces dose-dependent up-regulation of TNFSF6 on plasma …
Ionizing radiation modulates the expression of many plasma membrane-bound growth regulators, including the "death" ligand, TNFSF6 (fo …
The role of FasL and Fas in health and disease.
Ehrenschwender M, Wajant H. Ehrenschwender M, et al. Adv Exp Med Biol. 2009;647:64-93. doi: 10.1007/978-0-387-89520-8_5. Adv Exp Med Biol. 2009. PMID: 19760067 Review.
The groups of Shin Yonehara and Peter Krammer were the first reporting extensive apoptotic cell death induction upon treating cells with Fas-specific monoclonal antibodies.1,2 Cloning of Fas3 and its ligand,4,5 FasL (also known as CD178, CD95L or TNFSF6), laid the c …
The groups of Shin Yonehara and Peter Krammer were the first reporting extensive apoptotic cell death induction upon treating cells with Fas …
Insights into the molecular regulation of FasL (CD178) biology.
Lettau M, Paulsen M, Schmidt H, Janssen O. Lettau M, et al. Eur J Cell Biol. 2011 Jun-Jul;90(6-7):456-66. doi: 10.1016/j.ejcb.2010.10.006. Epub 2010 Dec 3. Eur J Cell Biol. 2011. PMID: 21126798 Review.
Fas ligand (FasL, CD95L, APO-1L, CD178, TNFSF6, APT1LG1) is the key death factor of receptor-triggered programmed cell death in immune cells. ...Many aspects of FasL biology have been ascribed to selective protein-protein interactions mediated by a unique pol …
Fas ligand (FasL, CD95L, APO-1L, CD178, TNFSF6, APT1LG1) is the key death factor of receptor-triggered programmed cell death i …
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