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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1991 4
1992 3
1993 11
1994 18
1995 16
1996 21
1997 24
1998 20
1999 13
2000 20
2001 30
2002 31
2003 27
2004 40
2005 47
2006 40
2007 46
2008 52
2009 59
2010 74
2011 80
2012 78
2013 86
2014 97
2015 86
2016 86
2017 96
2018 83
2019 92
2020 74
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1,299 results
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Page 1
Diagnosis and management of hyperinsulinaemic hypoglycaemia.
Galcheva S, Al-Khawaga S, Hussain K. Galcheva S, et al. Best Pract Res Clin Endocrinol Metab. 2018 Aug;32(4):551-573. doi: 10.1016/j.beem.2018.05.014. Epub 2018 Jun 6. Best Pract Res Clin Endocrinol Metab. 2018. PMID: 30086874 Review.
Recent advances in genetics have linked congenital HH to mutations in 14 different genes that play a key role in regulating insulin secretion (ABCC8, KCNJ11, GLUD1, GCK, HADH, SLC16A1, UCP2, HNF4A, HNF1A, HK1, PGM1, PPM2, CACNA1D, FOXA2). ...
Recent advances in genetics have linked congenital HH to mutations in 14 different genes that play a key role in regulating insulin secretio …
miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2-Versican Pathway.
Salem M, O'Brien JA, Bernaudo S, Shawer H, Ye G, Brkić J, Amleh A, Vanderhyden BC, Refky B, Yang BB, Krylov SN, Peng C. Salem M, et al. Cancer Res. 2018 Aug 1;78(15):4175-4190. doi: 10.1158/0008-5472.CAN-17-3014. Epub 2018 May 10. Cancer Res. 2018. PMID: 29748371 Free article.
Using a cDNA microarray, we identified forkhead box A2 (FOXA2) and versican (VCAN) as top downregulated and upregulated genes by mir-590, respectively. miR-590-3p targeted FOXA2 3' UTR to suppress its expression. In addition, knockdown or knockout of FOXA2 en …
Using a cDNA microarray, we identified forkhead box A2 (FOXA2) and versican (VCAN) as top downregulated and upregulated genes by mir- …
Forkhead box a2 (FOXA2) is essential for uterine function and fertility.
Kelleher AM, Peng W, Pru JK, Pru CA, DeMayo FJ, Spencer TE. Kelleher AM, et al. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E1018-E1026. doi: 10.1073/pnas.1618433114. Epub 2017 Jan 3. Proc Natl Acad Sci U S A. 2017. PMID: 28049832 Free PMC article.
The uteri of adult FOXA2-deleted mice were morphologically normal and contained glands, whereas the uteri of neonatal FOXA2-deleted mice were completely aglandular. ...Although pregnancy was rescued by LIF and was maintained to term in uterine gland-containing adult …
The uteri of adult FOXA2-deleted mice were morphologically normal and contained glands, whereas the uteri of neonatal FOXA2-de …
Congenital Hyperinsulinism and Hypopituitarism Attributable to a Mutation in FOXA2.
Vajravelu ME, Chai J, Krock B, Baker S, Langdon D, Alter C, De León DD. Vajravelu ME, et al. J Clin Endocrinol Metab. 2018 Mar 1;103(3):1042-1047. doi: 10.1210/jc.2017-02157. J Clin Endocrinol Metab. 2018. PMID: 29329447 Free PMC article.
Forkhead box A2 (Foxa2) is a transcription factor shown in mouse models to influence insulin secretion by pancreatic β cells. In addition, Foxa2 is involved in regulation of pituitary development, and deletions of FOXA2 have been linked to panhypopituitarism. …
Forkhead box A2 (Foxa2) is a transcription factor shown in mouse models to influence insulin secretion by pancreatic β cells. In addi …
Opposing Roles of the Forkhead Box Factors FoxM1 and FoxA2 in Liver Cancer.
Chand V, Pandey A, Kopanja D, Guzman G, Raychaudhuri P. Chand V, et al. Mol Cancer Res. 2019 May;17(5):1063-1074. doi: 10.1158/1541-7786.MCR-18-0968. Epub 2019 Feb 27. Mol Cancer Res. 2019. PMID: 30814128 Free PMC article.
First, the expression patterns of FoxM1 and FoxA2 in human HCC are opposite. We show that FoxM1 represses expression of FoxA2 in G(1) phase. ...Conversely, FoxA2 inhibits expression of FoxM1 and inhibits FoxM1-induced tumorigenicity. Also, FoxA2 inhibi …
First, the expression patterns of FoxM1 and FoxA2 in human HCC are opposite. We show that FoxM1 represses expression of FoxA2
Loss of FoxA2 accelerates neoplastic changes in the intrahepatic bile duct partly via the MAPK signaling pathway.
Shen J, Zhou Y, Zhang X, Peng W, Peng C, Zhou Q, Li C, Wen T, Shi Y. Shen J, et al. Aging (Albany NY). 2019 Nov 5;11(21):9280-9294. doi: 10.18632/aging.102332. Epub 2019 Nov 5. Aging (Albany NY). 2019. PMID: 31689237 Free PMC article.
FOXA2 is an archetypal transcription factor involved in cholangiocyte proliferation. RESULTS: FOXA2 expression was negatively correlated with tumor stage (p = 0.024). ...CONCLUSION: Low FOXA2 expression negatively affected the prognosis of patients with ICC.
FOXA2 is an archetypal transcription factor involved in cholangiocyte proliferation. RESULTS: FOXA2 expression was negatively
FOXA2 controls the cis-regulatory networks of pancreatic cancer cells in a differentiation grade-specific manner.
Milan M, Balestrieri C, Alfarano G, Polletti S, Prosperini E, Spaggiari P, Zerbi A, Diaferia GR, Natoli G. Milan M, et al. EMBO J. 2019 Oct 15;38(20):e102161. doi: 10.15252/embj.2019102161. Epub 2019 Sep 17. EMBO J. 2019. PMID: 31531882
We found that FOXA2, a TF controlling pancreas specification, broadly contributed to the cis-regulatory networks of PDACs. Despite being expressed in both well- and poorly differentiated PDAC cells, FOXA2 displayed extensively different genomic distributions and con …
We found that FOXA2, a TF controlling pancreas specification, broadly contributed to the cis-regulatory networks of PDACs. Despite be …
The nuclear bile acid receptor FXR is a PKA- and FOXA2-sensitive activator of fasting hepatic gluconeogenesis.
Ploton M, Mazuy C, Gheeraert C, Dubois V, Berthier A, Dubois-Chevalier J, Maréchal X, Bantubungi K, Diemer H, Cianférani S, Strub JM, Helleboid-Chapman A, Eeckhoute J, Staels B, Lefebvre P. Ploton M, et al. J Hepatol. 2018 Nov;69(5):1099-1109. doi: 10.1016/j.jhep.2018.06.022. Epub 2018 Jul 5. J Hepatol. 2018. PMID: 29981427 Free article.
The interaction of FOXA2 with FXR was identified by cistromic approaches and in vitro protein-protein interaction assays. The functional impact of the crosstalk between FXR, the PKA and FOXA2 signaling pathways was assessed by site-directed mutagenesis, transactivat …
The interaction of FOXA2 with FXR was identified by cistromic approaches and in vitro protein-protein interaction assays. The functio …
LINC00261 and the Adjacent Gene FOXA2 Are Epithelial Markers and Are Suppressed during Lung Cancer Tumorigenesis and Progression.
Dhamija S, Becker AC, Sharma Y, Myacheva K, Seiler J, Diederichs S. Dhamija S, et al. Noncoding RNA. 2018 Dec 28;5(1):2. doi: 10.3390/ncrna5010002. Noncoding RNA. 2018. PMID: 30597925 Free PMC article.
Moreover, the gene pair of LINC00261 and its neighbor FOXA2 were significantly co-regulated. LINC00261 as well as FOXA2 negatively correlated with markers for epithelial-to-mesenchymal transition (EMT) and were suppressed by the EMT inducer TGFβ. ...Furthermore, hig …
Moreover, the gene pair of LINC00261 and its neighbor FOXA2 were significantly co-regulated. LINC00261 as well as FOXA2 negati …
Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium.
Kelleher AM, Behura SK, Burns GW, Young SL, DeMayo FJ, Spencer TE. Kelleher AM, et al. FASEB J. 2019 Jul;33(7):8543-8554. doi: 10.1096/fj.201900013R. Epub 2019 Apr 5. FASEB J. 2019. PMID: 30951376 Free PMC article.
In mice, FOXA2 is a critical regulator of uterine gland development in the neonate and gland function in the adult. An integrative approach was used here to define the FOXA2 cistrome in the human endometrium. ...Integrative analysis of the forkhead box A2 (FOXA2
In mice, FOXA2 is a critical regulator of uterine gland development in the neonate and gland function in the adult. An integrative ap …
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