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HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry.
Henriksen EKK, Viken MK, Wittig M, Holm K, Folseraas T, Mucha S, Melum E, Hov JR, Lazaridis KN, Juran BD, Chazouillères O, Färkkilä M, Gotthardt DN, Invernizzi P, Carbone M, Hirschfield GM, Rushbrook SM, Goode E; UK-PSC Consortium, Ponsioen CY, Weersma RK, Eksteen B, Yimam KK, Gordon SC, Goldberg D, Yu L, Bowlus CL, Franke A, Lie BA, Karlsen TH. Henriksen EKK, et al. HLA. 2017 Oct;90(4):228-233. doi: 10.1111/tan.13076. Epub 2017 Jul 11. HLA. 2017. PMID: 28695657 Free PMC article.
Primary sclerosing cholangitis (PSC) is strongly associated with several human leukocyte antigen (HLA) haplotypes. ...We aimed to evaluate whether studying populations of admixed or non-European descent could help in defining the causative HLA a
Primary sclerosing cholangitis (PSC) is strongly associated with several human leukocyte antigen (HLA) haplotype
HLA DPB polymorphism in primary sclerosing cholangitis and primary biliary cirrhosis.
Underhill JA, Donaldson PT, Doherty DG, Manabe K, Williams R. Underhill JA, et al. Hepatology. 1995 Apr;21(4):959-62. Hepatology. 1995. PMID: 7705806
Polymerase chain reaction sequence-specific oligonucleotide probing was used to assign 18 DPB1 alleles in 82 patients with primary biliary cirrhosis (PBC), 71 patients with primary sclerosing cholangitis (PSC), and 103 controls. ...These data clearly d …
Polymerase chain reaction sequence-specific oligonucleotide probing was used to assign 18 DPB1 alleles in 82 patients with primary bi …
Different HLA class II associations in ulcerative colitis patients with and without primary sclerosing cholangitis.
Karlsen TH, Boberg KM, Vatn M, Bergquist A, Hampe J, Schrumpf E, Thorsby E, Schreiber S, Lie BA; IBSEN Study Group. Karlsen TH, et al. Genes Immun. 2007 Apr;8(3):275-8. doi: 10.1038/sj.gene.6364377. Epub 2007 Feb 15. Genes Immun. 2007. PMID: 17301827
Approximately 80% of patients with primary sclerosing cholangitis (PSC) of Northern European origin have inflammatory bowel disease (IBD), the majority ulcerative colitis (UC). ...This suggests different HLA associated genetic susceptibility to PSC and …
Approximately 80% of patients with primary sclerosing cholangitis (PSC) of Northern European origin have inflammatory b …
Novel association of HLA-haplotypes with primary sclerosing cholangitis (PSC) in a southern European population.
Neri TM, Cavestro GM, Seghini P, Zanelli PF, Zanetti A, Savi M, Podda M, Zuin M, Colombo M, Floreani A, Rosina F, Bianchi Porro G, Strazzabosco M, Okolicsanyi L. Neri TM, et al. Dig Liver Dis. 2003 Aug;35(8):571-6. doi: 10.1016/s1590-8658(03)00274-3. Dig Liver Dis. 2003. PMID: 14567462
AIMS: In patients with with primary sclerosing cholangitis we investigated the major histocompatibility complex (MHC) genes and mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. METHODS: In 64 PSC patients and 183 normal contro …
AIMS: In patients with with primary sclerosing cholangitis we investigated the major histocompatibility complex (MHC) g …
Combined HLA-DR and -DQ disparity is associated with a stable course of ulcerative colitis after liver transplantation for primary sclerosing cholangitis.
Cholongitas E, Papatheodoridis GV, Zappoli P, Giannakopoulos A, Patch D, Marelli L, Shusang V, Kalambokis G, Shirling G, Rolando N, Burroughs AK. Cholongitas E, et al. Liver Transpl. 2007 Apr;13(4):552-7. doi: 10.1002/lt.21077. Liver Transpl. 2007. PMID: 17394153 Free article.
We evaluated whether donor-recipient HLA disparity after liver transplantation (LT) affects UC in patients with primary sclerosing cholangitis (PSC). ...We conclude that disparity in both HLA-DR and -DQ between donor and recipient is asso …
We evaluated whether donor-recipient HLA disparity after liver transplantation (LT) affects UC in patients with primary scl
Association of primary sclerosing cholangitis, ulcerative colitis and coeliac disease in female siblings.
Habior A, Rawa T, Orłowska J, Sankowska M, Lewartowska A, Tilszer A, Pawlak J, Krawczyk M, Butruk E. Habior A, et al. Eur J Gastroenterol Hepatol. 2002 Jul;14(7):787-91. doi: 10.1097/00042737-200207000-00014. Eur J Gastroenterol Hepatol. 2002. PMID: 12169991
Primary sclerosing cholangitis is a rare, cholestatic liver disease, most commonly affecting young men. ...We describe, for the first time, the association of primary sclerosing cholangitis, ulcerative colitis and coeliac disease in two s
Primary sclerosing cholangitis is a rare, cholestatic liver disease, most commonly affecting young men. ...We describe,
Evaluation of the role of MHC class II alleles, haplotypes and selected amino acid sequences in primary sclerosing cholangitis.
Donaldson PT, Norris S. Donaldson PT, et al. Autoimmunity. 2002 Dec;35(8):555-64. doi: 10.1080/0891693021000054093. Autoimmunity. 2002. PMID: 12765483
BACKGROUND AND AIMS: Genetic susceptibility to primary sclerosing cholangitis is associated with several different HLA haplotypes, though a single "shared" susceptibility allele has yet to be identified. ...The present study re-examines HLA clas …
BACKGROUND AND AIMS: Genetic susceptibility to primary sclerosing cholangitis is associated with several different H
HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations.
Spurkland A, Saarinen S, Boberg KM, Mitchell S, Broome U, Caballeria L, Ciusani E, Chapman R, Ercilla G, Fausa O, Knutsen I, Pares A, Rosina F, Olerup O, Thorsby E, Schrumpf E. Spurkland A, et al. Tissue Antigens. 1999 May;53(5):459-69. doi: 10.1034/j.1399-0039.1999.530502.x. Tissue Antigens. 1999. PMID: 10372541
The association of primary sclerosing cholangitis (PSC) to HLA class II genes was studied by comparing patients from five different European populations. ...Thus, PSC was found to be positively associated to three different HLA class II haplotyp …
The association of primary sclerosing cholangitis (PSC) to HLA class II genes was studied by comparing patients …
HLA class II genes in primary sclerosing cholangitis and chronic inflammatory bowel disease: no HLA-DRw52a association in Swedish patients with sclerosing cholangitis.
Zetterquist H, Broomé U, Einarsson K, Olerup O. Zetterquist H, et al. Gut. 1992 Jul;33(7):942-6. doi: 10.1136/gut.33.7.942. Gut. 1992. PMID: 1644334 Free PMC article.
HLA class II alleles of the DR, DQ, and DP subregions were determined by genomic typing techniques in a large group of Swedish patients with ulcerative colitis or Crohn's disease as well as in a series of patients with primary sclerosing cholangitis
HLA class II alleles of the DR, DQ, and DP subregions were determined by genomic typing techniques in a large group of Swedish
A patient with hereditary hemochromatosis, ulcerative colitis, and primary sclerosing cholangitis: genetic aspects.
Ponsioen CY, Stokkers PC, vd Horst AR, Tytgat GN, van Deventer SJ. Ponsioen CY, et al. Eur J Intern Med. 2001 Dec;12(6):518-21. doi: 10.1016/s0953-6205(01)00179-0. Eur J Intern Med. 2001. PMID: 11711276
This report describes a family in which the rare combination of hereditary hemochromatosis, ulcerative colitis and primary sclerosing cholangitis was found. Subsequent to the index patient, who had all three diseases, a screening was done in his parents and s …
This report describes a family in which the rare combination of hereditary hemochromatosis, ulcerative colitis and primary scleros
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