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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 1
1983 5
1984 3
1985 5
1986 3
1987 6
1988 10
1989 6
1990 10
1991 7
1992 7
1993 7
1994 6
1995 5
1996 9
1997 9
1998 7
1999 11
2000 6
2001 7
2002 3
2003 8
2004 6
2005 7
2006 5
2007 8
2008 6
2009 4
2010 1
2011 3
2012 9
2013 10
2014 3
2015 5
2016 4
2017 6
2018 4
2019 5
2020 5
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223 results
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Page 1
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.
Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy NA, Kupcinskas L, Lawrance IC, Lee JC, Satsangi J, Schreiber S, Théâtre E, van der Meulen-de Jong AE, Weersma RK, Wilson DC; International Inflammatory Bowel Disease Genetics Consortium, Parkes M, Vermeire S, Rioux JD, Mansfield J, Silverberg MS, Radford-Smith G, McGovern DP, Barrett JC, Lees CW. Cleynen I, et al. Lancet. 2016 Jan 9;387(10014):156-67. doi: 10.1016/S0140-6736(15)00465-1. Epub 2015 Oct 18. Lancet. 2016. PMID: 26490195 Free PMC article.
Genetic studies have identified 163 susceptibility loci for inflammatory bowel disease, mostly shared between Crohn's disease and ulcerative colitis. ...INTERPRETATION: Our data support a continuum of disorders within inflammatory bowel disease, much b …
Genetic studies have identified 163 susceptibility loci for inflammatory bowel disease, mostly shared between Crohn's disea
HLA-DR and -DQ phenotypes in inflammatory bowel disease: a meta-analysis.
Stokkers PC, Reitsma PH, Tytgat GN, van Deventer SJ. Stokkers PC, et al. Gut. 1999 Sep;45(3):395-401. doi: 10.1136/gut.45.3.395. Gut. 1999. PMID: 10446108 Free PMC article.
Multiple studies have reported associations between HLA-DR or -DQ phenotypes and either ulcerative colitis or Crohn's disease, but much of the data are still controversial. AIMS: To estimate overall associations between HLA class II phenotypes a …
Multiple studies have reported associations between HLA-DR or -DQ phenotypes and either ulcerative colitis or Crohn's …
HLA-linked susceptibility and resistance genes in Crohn's disease.
Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. Nakajima A, et al. Gastroenterology. 1995 Nov;109(5):1462-7. doi: 10.1016/0016-5085(95)90631-2. Gastroenterology. 1995. PMID: 7557126
BACKGROUND & AIMS: Previous studies have shown a positive association of HLA-DR4-DQ4 with Crohn's disease in the Japanese population, but the association between Crohn's disease and HLA genes has yet to be fully elucidated. The aim of …
BACKGROUND & AIMS: Previous studies have shown a positive association of HLA-DR4-DQ4 with Crohn's disease in the Ja …
Obliterative arteritis with nitric oxide synthase and HLA-DR expression in Crohn's colitis.
Yokoyama K, Mitomi H, Kobayashi K, Katsumata T, Saigenji K, Okayasu I. Yokoyama K, et al. Hepatogastroenterology. 2001 Mar-Apr;48(38):401-7. Hepatogastroenterology. 2001. PMID: 11379318
In addition, focally enhanced endothelial staining of HLA-DR, with expression in granulomas adjacent to vessels was occasionally observed. In the endothelium of affected vessels, strong expression of HLA-DR was more prevalent in Crohn's disea
In addition, focally enhanced endothelial staining of HLA-DR, with expression in granulomas adjacent to vessels was occasional …
Association of human leucocyte DR and DQ antigens in Crohn's disease in Asian Indians: a family study.
Thakur S, Ranjan P, Ghoshal UC, Muller-Myhsok B, Khan F, Talwar S, Agarwal S. Thakur S, et al. Trop Gastroenterol. 2003 Oct-Dec;24(4):185-8. Trop Gastroenterol. 2003. PMID: 15164528
The pathogenesis of Crohn's disease (CD) involves an abnormal immune response to enteric bacteria in genetically susceptible individuals. ...Crohn disease is not associated with HLA class II antigens in Indian patients. Genes of the major …
The pathogenesis of Crohn's disease (CD) involves an abnormal immune response to enteric bacteria in genetically susceptible i …
IBD1 and IBD3 determine location of Crohn's disease in the Spanish population.
Fernandez L, Mendoza JL, Martinez A, Urcelay E, Fernandez-Arquero M, Garcia-Paredes J, Peña AS, Diaz-Rubio M, de la Concha EG. Fernandez L, et al. Inflamm Bowel Dis. 2004 Nov;10(6):715-22. doi: 10.1097/00054725-200411000-00004. Inflamm Bowel Dis. 2004. PMID: 15626888
RESULTS: NOD2/CARD15 mutations and HLA-DRB1*07 confer susceptibility only to the ileal location of the disease, whereas HLA-DRB1*0103 is associated only with the colonic location of the disease. ...This appears to be true for both inflammatory bowel di …
RESULTS: NOD2/CARD15 mutations and HLA-DRB1*07 confer susceptibility only to the ileal location of the disease, whereas HLA
HLA-DR antigens on colonic epithelial cells in inflammatory bowel disease: I. Relation to the state of activation of lamina propria lymphocytes and to the epithelial expression of other surface markers.
Fais S, Pallone F, Squarcia O, Biancone L, Ricci F, Paoluzi P, Boirivant M. Fais S, et al. Clin Exp Immunol. 1987 Jun;68(3):605-12. Clin Exp Immunol. 1987. PMID: 3308219 Free PMC article.
The colonic epithelial expression of HLA-DR molecules and of other markers of cell membrane perturbation was investigated by immunofluorescence in biopsy specimens from patients with ulcerative colitis and Crohn's disease. ...There was no relation betw …
The colonic epithelial expression of HLA-DR molecules and of other markers of cell membrane perturbation was investigated by i …
Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease.
Mitsialis V, Wall S, Liu P, Ordovas-Montanes J, Parmet T, Vukovic M, Spencer D, Field M, McCourt C, Toothaker J, Bousvaros A; Boston Children’s Hospital Inflammatory Bowel Disease Center; Brigham and Women’s Hospital Crohn’s and Colitis Center, Shalek AK, Kean L, Horwitz B, Goldsmith J, Tseng G, Snapper SB, Konnikova L. Mitsialis V, et al. Gastroenterology. 2020 Aug;159(2):591-608.e10. doi: 10.1053/j.gastro.2020.04.074. Epub 2020 May 16. Gastroenterology. 2020. PMID: 32428507
BACKGROUND & AIMS: Studies are needed to determine the mechanisms of mucosal dysregulation in patients with inflammatory bowel diseases (IBDs) and differences in inflammatory responses of patients with ulcerative colitis (UC) vs Crohn's disease (CD). ...Mucosal …
BACKGROUND & AIMS: Studies are needed to determine the mechanisms of mucosal dysregulation in patients with inflammatory bowel diseases …
Aberrant esophageal HLA-DR expression in a high percentage of patients with Crohn's disease.
Oberhuber G, Püspök A, Peck-Radosavlevic M, Kutilek M, Lamprecht A, Chott A, Vogelsang H, Stolte M. Oberhuber G, et al. Am J Surg Pathol. 1999 Aug;23(8):970-6. doi: 10.1097/00000478-199908000-00016. Am J Surg Pathol. 1999. PMID: 10435568
Esophageal histology is not well studied in patients with Crohn's disease (CD). We, therefore, analyzed the histologic and immunohistologic appearance of esophageal mucosa in CD. ...In controls, most patients had either HLA-DR negative esophageal epith …
Esophageal histology is not well studied in patients with Crohn's disease (CD). We, therefore, analyzed the histologic and imm …
HLA antigens and anti-neutrophil cytoplasmic antibodies (ANCA) in inflammatory bowel disease.
García Herola A, Nos P, Hinijosa J, Hoyos M, Molés JR, Carmona E, Puig N, Sánchez-Cuenca JM, Ponce J, Berenguer J. García Herola A, et al. Rev Esp Enferm Dig. 2003 Nov;95(11):760-4, 755-9. Rev Esp Enferm Dig. 2003. PMID: 14640873 Free article. English, Spanish.
HLA class I (A and B) and II (DR) antigens were studied by serological techniques. Detection of ANCA was carried out in all patients by an indirect immunofluorescence method. ...RESULTS: we found a significant increased frequency of HLA-DR2 in patients
HLA class I (A and B) and II (DR) antigens were studied by serological techniques. Detection of ANCA was carried out in
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