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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 3
1983 5
1984 2
1985 3
1986 3
1987 5
1988 3
1989 6
1990 8
1991 9
1992 7
1993 8
1994 8
1995 9
1996 10
1997 16
1998 9
1999 12
2000 8
2001 10
2002 9
2003 11
2004 5
2005 8
2006 4
2007 12
2008 8
2009 5
2010 2
2011 3
2012 7
2013 8
2014 3
2015 7
2016 7
2017 5
2018 5
2019 2
2020 4
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250 results
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Page 1
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.
Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy NA, Kupcinskas L, Lawrance IC, Lee JC, Satsangi J, Schreiber S, Théâtre E, van der Meulen-de Jong AE, Weersma RK, Wilson DC; International Inflammatory Bowel Disease Genetics Consortium, Parkes M, Vermeire S, Rioux JD, Mansfield J, Silverberg MS, Radford-Smith G, McGovern DP, Barrett JC, Lees CW. Cleynen I, et al. Lancet. 2016 Jan 9;387(10014):156-67. doi: 10.1016/S0140-6736(15)00465-1. Epub 2015 Oct 18. Lancet. 2016. PMID: 26490195 Free PMC article. Clinical Trial.
Genetic studies have identified 163 susceptibility loci for inflammatory bowel disease, mostly shared between Crohn's disease and ulcerative colitis. ...INTERPRETATION: Our data support a continuum of disorders within inflammatory bowel disease, much better explaine …
Genetic studies have identified 163 susceptibility loci for inflammatory bowel disease, mostly shared between Crohn's disease and ulcerat
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.
Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S; International Inflammatory Bowel Disease Genetics Consortium; Australia and New Zealand IBDGC; Belgium IBD Genetics Consortium; Italian Group for IBD Genetic Consortium; NIDDK Inflammatory Bowel Disease Genetics Consortium; United Kingdom IBDGC; Wellcome Trust Case Control Consortium; Quebec IBD Genetics Consortium, Daly MJ, Van Steen K, Duerr RH, Barrett JC, McGovern DP, Schumm LP, Traherne JA, Carrington MN, Kosmoliaptsis V, Karlsen TH, Franke A, Rioux JD. Goyette P, et al. Nat Genet. 2015 Feb;47(2):172-9. doi: 10.1038/ng.3176. Epub 2015 Jan 5. Nat Genet. 2015. PMID: 25559196 Free PMC article.
To address this, we performed high-density SNP typing of the MHC in >32,000 individuals with IBD, implicating multiple HLA alleles, with a primary role for HLA-DRB1*01:03 in both Crohn's disease and ulcerative colitis. Noteworthy differences were ob …
To address this, we performed high-density SNP typing of the MHC in >32,000 individuals with IBD, implicating multiple HLA alleles …
Effects of smoking on the association of human leukocyte antigen with ulcerative colitis.
Lee HS, Kim K, Jung S, Hong M, Kim BM, Yoo DS, Moon JW, Baek J, Hwang SW, Park SH, Yang SK, Han B, Song K, Ye BD. Lee HS, et al. J Gastroenterol Hepatol. 2019 Oct;34(10):1777-1783. doi: 10.1111/jgh.14695. Epub 2019 Jun 19. J Gastroenterol Hepatol. 2019. PMID: 31038770
However, smoking has been found to be protective against ulcerative colitis (UC). Human leukocyte antigen (HLA) is a major susceptibility locus for UC, and HLA-DRB1*15:02 has the strongest effect in Asians. ...CONCLUSIONS: An association between UC and …
However, smoking has been found to be protective against ulcerative colitis (UC). Human leukocyte antigen (HLA) is a ma …
Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis.
Venkateswaran S, Prince J, Cutler DJ, Marigorta UM, Okou DT, Prahalad S, Mack D, Boyle B, Walters T, Griffiths A, Sauer CG, LeLeiko N, Keljo D, Markowitz J, Baker SS, Rosh J, Pfefferkorn M, Heyman MB, Patel A, Otley A, Baldassano R, Noe J, Rufo P, Oliva-Hemker M, Davis S, Zwick ME, Gibson G, Denson LA, Hyams J, Kugathasan S. Venkateswaran S, et al. Inflamm Bowel Dis. 2018 Mar 19;24(4):829-838. doi: 10.1093/ibd/izx084. Inflamm Bowel Dis. 2018. PMID: 29562276 Free PMC article.
BACKGROUND: The genetic contributions to pediatric onset ulcerative colitis (UC), characterized by severe disease and extensive colonic involvement, are largely unknown. ...CONCLUSION: In pediatric onset UC, the HLA explains almost the entire genetic associat …
BACKGROUND: The genetic contributions to pediatric onset ulcerative colitis (UC), characterized by severe disease and extensiv …
Association of HLA-DRB1 Alleles with Ulcerative Colitis in the City of Kerman, South Eastern Iran.
Mohammadi M, Rastin M, Rafatpanah H, Abdoli Sereshki H, Zahedi MJ, Nikpoor AR, Baneshi MR, Hayatbakhsh MM. Mohammadi M, et al. Iran J Allergy Asthma Immunol. 2015 Jun;14(3):306-12. Iran J Allergy Asthma Immunol. 2015. PMID: 26546900 Free article.
The association of HLA class II genes with ulcerative colitis (UC) as an autoimmune disease has been investigated for several years. ...HLA-DRB1*04 was negatively associated with UC. Furthermore, HLA-DRB1*13 was significantly associated with sev …
The association of HLA class II genes with ulcerative colitis (UC) as an autoimmune disease has been investigated for s …
Expression of HLA-DR antigens on colonic epithelium in ulcerative colitis.
Iizuka M, Chiba M, Ohta H, Kodama K, Igarashi K, Arakawa H, Masamune O. Iizuka M, et al. Gastroenterol Jpn. 1987 Oct;22(5):571-7. doi: 10.1007/BF02776716. Gastroenterol Jpn. 1987. PMID: 3315818
HLA-DR antigens were detected by indirect peroxidase staining using anti-HLA-DR monoclonal antibody. We confirmed the previous observation that epithelium from control colon does not express HLA-DR antigens, while epithelium
HLA-DR antigens were detected by indirect peroxidase staining using anti-HLA-DR monoclonal antibody. We c
Distinct patterns of naive, activated and memory T and B cells in blood of patients with ulcerative colitis or Crohn's disease.
Rabe H, Malmquist M, Barkman C, Östman S, Gjertsson I, Saalman R, Wold AE. Rabe H, et al. Clin Exp Immunol. 2019 Jul;197(1):111-129. doi: 10.1111/cei.13294. Epub 2019 Apr 8. Clin Exp Immunol. 2019. PMID: 30883691 Free PMC article.
Ulcerative colitis was characterized by activated T cells, primarily in the CD8(+) population, as judged by increased expression of human leukocyte antigen D-related (HLA-DR) and the β1-integrins [very late antigen (VLA)] and a reduced proportion of na
Ulcerative colitis was characterized by activated T cells, primarily in the CD8(+) population, as judged by increased expressi
Molecularly defined HLA-DR2 alleles in ulcerative colitis and an antineutrophil cytoplasmic antibody-positive subgroup.
Duerr RH, Neigut DA. Duerr RH, et al. Gastroenterology. 1995 Feb;108(2):423-7. doi: 10.1016/0016-5085(95)90069-1. Gastroenterology. 1995. PMID: 7835583
BACKGROUND/AIMS: Although HLA-DR2 is associated with Japanese ulcerative colitis, data regarding an HLA-DR2 association in other populations are conflicting. A recent study suggests that HLA-DR2 is only associated with antineutrophil cytoplasmic …
BACKGROUND/AIMS: Although HLA-DR2 is associated with Japanese ulcerative colitis, data regarding an HLA-DR2 asso …
Different HLA class II associations in ulcerative colitis patients with and without primary sclerosing cholangitis.
Karlsen TH, Boberg KM, Vatn M, Bergquist A, Hampe J, Schrumpf E, Thorsby E, Schreiber S, Lie BA; IBSEN Study Group. Karlsen TH, et al. Genes Immun. 2007 Apr;8(3):275-8. doi: 10.1038/sj.gene.6364377. Epub 2007 Feb 15. Genes Immun. 2007. PMID: 17301827 Clinical Trial.
Approximately 80% of patients with primary sclerosing cholangitis (PSC) of Northern European origin have inflammatory bowel disease (IBD), the majority ulcerative colitis (UC). ...We aimed to clarify to what extent human leukocyte antigen (HLA) class II assoc …
Approximately 80% of patients with primary sclerosing cholangitis (PSC) of Northern European origin have inflammatory bowel disease (IBD), t …
Positive and negative associations of distinct HLA-DR2 subtypes with ulcerative colitis (UC).
De La Concha EG, Fernandez-Arquero M, Santa-Cruz S, Lopez-Nava G, Figueredo MA, Diaz-Rubio M, Garcia-Paredes J. De La Concha EG, et al. Clin Exp Immunol. 1997 Jun;108(3):392-5. doi: 10.1046/j.1365-2249.1997.3951285.x. Clin Exp Immunol. 1997. PMID: 9182881 Free PMC article.
Patients with ulcerative colitis (n = 107) and 200 controls were typed using molecular, DNA-based techniques for HLA-DRB1, DQA1 and DQB1 alleles. ...Moreover, HLA-DR3 and HLA-DQB1*02 are associated negatively....
Patients with ulcerative colitis (n = 107) and 200 controls were typed using molecular, DNA-based techniques for HLA-DR …
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