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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 2
1996 6
1997 3
1998 2
1999 3
2000 4
2001 2
2002 1
2003 2
2004 3
2005 4
2006 2
2007 2
2008 2
2009 2
2011 1
2012 3
2013 1
2014 2
2015 4
2016 3
2017 2
2018 7
2019 4
2020 2
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66 results
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Page 1
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.
Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy NA, Kupcinskas L, Lawrance IC, Lee JC, Satsangi J, Schreiber S, Théâtre E, van der Meulen-de Jong AE, Weersma RK, Wilson DC; International Inflammatory Bowel Disease Genetics Consortium, Parkes M, Vermeire S, Rioux JD, Mansfield J, Silverberg MS, Radford-Smith G, McGovern DP, Barrett JC, Lees CW. Cleynen I, et al. Lancet. 2016 Jan 9;387(10014):156-67. doi: 10.1016/S0140-6736(15)00465-1. Epub 2015 Oct 18. Lancet. 2016. PMID: 26490195 Free PMC article. Clinical Trial.
Genetic studies have identified 163 susceptibility loci for inflammatory bowel disease, mostly shared between Crohn's disease and ulcerative colitis. ...INTERPRETATION: Our data support a continuum of disorders within inflammatory bowel disease, much b …
Genetic studies have identified 163 susceptibility loci for inflammatory bowel disease, mostly shared between Crohn's disea
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.
Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S; International Inflammatory Bowel Disease Genetics Consortium; Australia and New Zealand IBDGC; Belgium IBD Genetics Consortium; Italian Group for IBD Genetic Consortium; NIDDK Inflammatory Bowel Disease Genetics Consortium; United Kingdom IBDGC; Wellcome Trust Case Control Consortium; Quebec IBD Genetics Consortium, Daly MJ, Van Steen K, Duerr RH, Barrett JC, McGovern DP, Schumm LP, Traherne JA, Carrington MN, Kosmoliaptsis V, Karlsen TH, Franke A, Rioux JD. Goyette P, et al. Nat Genet. 2015 Feb;47(2):172-9. doi: 10.1038/ng.3176. Epub 2015 Jan 5. Nat Genet. 2015. PMID: 25559196 Free PMC article.
Genome-wide association studies of the related chronic inflammatory bowel diseases (IBD) known as Crohn's disease and ulcerative colitis have shown strong evidence of association to the major histocompatibility complex (MHC). ...To address this, we performed high-de …
Genome-wide association studies of the related chronic inflammatory bowel diseases (IBD) known as Crohn's disease and ulcerati …
Vimentin as antigenic target in autoimmunity: A comprehensive review.
Musaelyan A, Lapin S, Nazarov V, Tkachenko O, Gilburd B, Mazing A, Mikhailova L, Shoenfeld Y. Musaelyan A, et al. Autoimmun Rev. 2018 Sep;17(9):926-934. doi: 10.1016/j.autrev.2018.04.004. Epub 2018 Jul 17. Autoimmun Rev. 2018. PMID: 30009963 Review.
Epitopes of native vimentin are antigenic in the group of HLA-DRB1*0301 positive patients with sarcoidosis. In addition, vimentin takes part in pathogenesis of tubulointerstitial inflammation and glomerulonephritis in lupus. ...Post-translationally modified form of …
Epitopes of native vimentin are antigenic in the group of HLA-DRB1*0301 positive patients with sarcoidosis. In addition, vimen …
HLA-linked susceptibility and resistance genes in Crohn's disease.
Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A. Nakajima A, et al. Gastroenterology. 1995 Nov;109(5):1462-7. doi: 10.1016/0016-5085(95)90631-2. Gastroenterology. 1995. PMID: 7557126
BACKGROUND & AIMS: Previous studies have shown a positive association of HLA-DR4-DQ4 with Crohn's disease in the Japanese population, but the association between Crohn's disease and HLA genes has yet to be fully elucidated. ...RESULTS …
BACKGROUND & AIMS: Previous studies have shown a positive association of HLA-DR4-DQ4 with Crohn's disease in the Ja …
Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.
Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, Herrinton LJ, Klapproth JA, Quiros AJ, Seminerio J, Liu Z, Alexander JS, Baldassano RN, Dudley-Brown S, Cross RK, Dassopoulos T, Denson LA, Dhere TA, Dryden GW, Hanson JS, Hou JK, Hussain SZ, Hyams JS, Isaacs KL, Kader H, Kappelman MD, Katz J, Kellermayer R, Kirschner BS, Kuemmerle JF, Kwon JH, Lazarev M, Li E, Mack D, Mannon P, Moulton DE, Newberry RD, Osuntokun BO, Patel AS, Saeed SA, Targan SR, Valentine JF, Wang MH, Zonca M, Rioux JD, Duerr RH, Silverberg MS, Cho JH, Hakonarson H, Zwick ME, McGovern DP, Kugathasan S. Brant SR, et al. Gastroenterology. 2017 Jan;152(1):206-217.e2. doi: 10.1053/j.gastro.2016.09.032. Epub 2016 Sep 28. Gastroenterology. 2017. PMID: 27693347 Free PMC article. Clinical Trial.
BACKGROUND & AIMS: The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn's disease (CD) cause significant morbidity and are increasing in prevalence among all populations, including African Americans. ...RESULTS: We detected SNPs at HLA- …
BACKGROUND & AIMS: The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn's disease (CD) cause significan …
IBD1 and IBD3 determine location of Crohn's disease in the Spanish population.
Fernandez L, Mendoza JL, Martinez A, Urcelay E, Fernandez-Arquero M, Garcia-Paredes J, Peña AS, Diaz-Rubio M, de la Concha EG. Fernandez L, et al. Inflamm Bowel Dis. 2004 Nov;10(6):715-22. doi: 10.1097/00054725-200411000-00004. Inflamm Bowel Dis. 2004. PMID: 15626888
RESULTS: NOD2/CARD15 mutations and HLA-DRB1*07 confer susceptibility only to the ileal location of the disease, whereas HLA-DRB1*0103 is associated only with the colonic location of the disease. ...This appears to be true for both inflamm …
RESULTS: NOD2/CARD15 mutations and HLA-DRB1*07 confer susceptibility only to the ileal location of the disease, whereas …
HLA-DRB1 alleles may influence disease phenotype in patients with inflammatory bowel disease: a critical reappraisal with review of the literature.
Annese V, Piepoli A, Latiano A, Lombardi G, Napolitano G, Caruso N, Cocchiara E, Accadia L, Perri F, Andriulli A. Annese V, et al. Dis Colon Rectum. 2005 Jan;48(1):57-64; discussion 64-5. doi: 10.1007/s10350-004-0747-0. Dis Colon Rectum. 2005. PMID: 15690658 Review.
The aim of this study was to assess the relation between HLA-DRB1 alleles with the clinical features of Crohn's disease and ulcerative colitis and the presence of anti-neutrophil cytoplasmic and anti-Saccharomyces cerevisiae antibodies. ...RESULTS: As …
The aim of this study was to assess the relation between HLA-DRB1 alleles with the clinical features of Crohn's dise
Genetic associations of inflammatory bowel disease in a South Asian population.
Niriella MA, Liyanage IK, Kodisinghe SK, Silva AP, Rajapakshe N, Nanayakkara SD, Luke D, Silva T, Nawarathne M, Peiris RK, Kalubovila UP, Kumarasena SR, Dissanayake VHW, Jayasekara RW, de Silva HJ. Niriella MA, et al. World J Clin Cases. 2018 Dec 6;6(15):908-915. doi: 10.12998/wjcc.v6.i15.908. World J Clin Cases. 2018. PMID: 30568945 Free PMC article.
METHODS: A case study of histologically confirmed ulcerative colitis (UC) or Crohn's disease (CD) patients with ≥ 1 year disease duration, who were compared to unrelated, gender-matched, healthy individuals as controls, was conducted at four major centers in …
METHODS: A case study of histologically confirmed ulcerative colitis (UC) or Crohn's disease (CD) patients with ≥ 1 year di
CARD15 and HLA DRB1 alleles influence susceptibility and disease localization in Crohn's disease.
Newman B, Silverberg MS, Gu X, Zhang Q, Lazaro A, Steinhart AH, Greenberg GR, Griffiths AM, McLeod RS, Cohen Z, Fernández-Viña M, Amos CI, Siminovitch K. Newman B, et al. Am J Gastroenterol. 2004 Feb;99(2):306-15. doi: 10.1111/j.1572-0241.2004.04038.x. Am J Gastroenterol. 2004. PMID: 15046222
OBJECTIVES: Crohn's disease (CD) is a chronic inflammatory disease of the gut associated with allelic variants of CARD15 and HLA-DRB1 genes. ...By contrast, the HLA-DRB1*0103 allele was associated with later age of diagnosis (p = 0 …
OBJECTIVES: Crohn's disease (CD) is a chronic inflammatory disease of the gut associated with allelic variants of CARD1 …
Review article: the genetics of the human leucocyte antigen region in inflammatory bowel disease.
Ashton JJ, Latham K, Beattie RM, Ennis S. Ashton JJ, et al. Aliment Pharmacol Ther. 2019 Oct;50(8):885-900. doi: 10.1111/apt.15485. Epub 2019 Sep 13. Aliment Pharmacol Ther. 2019. PMID: 31518029 Review.
METHODS: An organised search strategy was used to collate articles describing HLA genes in IBD, including Crohn's disease and ulcerative colitis. ...The most implicated gene is HLA-DRB1, with HLA-DRB1*03:01 the most associated risk …
METHODS: An organised search strategy was used to collate articles describing HLA genes in IBD, including Crohn's disease
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