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Risk of recurrence of primary sclerosing cholangitis after liver transplantation is associated with de novo inflammatory bowel disease.
Bajer L, Slavcev A, Macinga P, Sticova E, Brezina J, Roder M, Janousek R, Trunecka P, Spicak J, Drastich P. Bajer L, et al. World J Gastroenterol. 2018 Nov 21;24(43):4939-4949. doi: 10.3748/wjg.v24.i43.4939. World J Gastroenterol. 2018. PMID: 30487703 Free PMC article.
AIM: To evaluate risk factors for primary sclerosing cholangitis (PSC) recurrence (rPSC) after orthotopic liver transplantation (OLT) in patients with well-preserved colons. ...According to the univariate analysis, overlapping features of autoimmune hepatitis …
AIM: To evaluate risk factors for primary sclerosing cholangitis (PSC) recurrence (rPSC) after orthotopic liver transpl …
HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation.
Fosby B, Næss S, Hov JR, Traherne J, Boberg KM, Trowsdale J, Foss A, Line PD, Franke A, Melum E, Scott H, Karlsen TH. Fosby B, et al. World J Gastroenterol. 2014 Apr 14;20(14):3986-4000. doi: 10.3748/wjg.v20.i14.3986. World J Gastroenterol. 2014. PMID: 24744588 Free PMC article.
Immunohistochemical staining for T (CD3), B (CD20) and natural killer (NK) cells (CD56 and CD57) were performed on liver biopsies from 3 different patient groups [primary sclerosing cholangitis (PSC), primary biliary cirrhosis and non-autoimmune liver …
Immunohistochemical staining for T (CD3), B (CD20) and natural killer (NK) cells (CD56 and CD57) were performed on liver biopsies from 3 dif …
HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry.
Henriksen EKK, Viken MK, Wittig M, Holm K, Folseraas T, Mucha S, Melum E, Hov JR, Lazaridis KN, Juran BD, Chazouillères O, Färkkilä M, Gotthardt DN, Invernizzi P, Carbone M, Hirschfield GM, Rushbrook SM, Goode E; UK-PSC Consortium, Ponsioen CY, Weersma RK, Eksteen B, Yimam KK, Gordon SC, Goldberg D, Yu L, Bowlus CL, Franke A, Lie BA, Karlsen TH. Henriksen EKK, et al. HLA. 2017 Oct;90(4):228-233. doi: 10.1111/tan.13076. Epub 2017 Jul 11. HLA. 2017. PMID: 28695657 Free PMC article.
Primary sclerosing cholangitis (PSC) is strongly associated with several human leukocyte antigen (HLA) haplotypes. Due to extensive linkage disequilibrium and multiple polymorphic candidate genes in the HLA complex, identifying the alleles respo
Primary sclerosing cholangitis (PSC) is strongly associated with several human leukocyte antigen (HLA) haplotype
Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis.
Hov JR, Boberg KM, Taraldsrud E, Vesterhus M, Boyadzhieva M, Solberg IC, Schrumpf E, Vatn MH, Lie BA, Molberg Ø, Karlsen TH. Hov JR, et al. Liver Int. 2017 Mar;37(3):458-465. doi: 10.1111/liv.13238. Epub 2016 Sep 13. Liver Int. 2017. PMID: 27558072
BACKGROUND & AIMS: The strongest genetic risk factors in primary sclerosing cholangitis (PSC) are encoded in the HLA complex. ...HLA-B and HLA-DRB1 genotyping was performed in the patients and in 368 healthy controls. Data on p …
BACKGROUND & AIMS: The strongest genetic risk factors in primary sclerosing cholangitis (PSC) are encoded in the …
HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations.
Spurkland A, Saarinen S, Boberg KM, Mitchell S, Broome U, Caballeria L, Ciusani E, Chapman R, Ercilla G, Fausa O, Knutsen I, Pares A, Rosina F, Olerup O, Thorsby E, Schrumpf E. Spurkland A, et al. Tissue Antigens. 1999 May;53(5):459-69. doi: 10.1034/j.1399-0039.1999.530502.x. Tissue Antigens. 1999. PMID: 10372541
The association of primary sclerosing cholangitis (PSC) to HLA class II genes was studied by comparing patients from five different European populations. ...Thus, PSC was found to be positively associated to three different HLA class II haplotyp …
The association of primary sclerosing cholangitis (PSC) to HLA class II genes was studied by comparing patients …
Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes.
Wiencke K, Karlsen TH, Boberg KM, Thorsby E, Schrumpf E, Lie BA, Spurkland A. Wiencke K, et al. Tissue Antigens. 2007 Feb;69(2):161-9. doi: 10.1111/j.1399-0039.2006.00738.x. Tissue Antigens. 2007. PMID: 17257319
Primary sclerosing cholangitis (PSC) is associated with the human leukocyte antigen (HLA)-DRB1*0301-DQA1*0501-DQB1*0201 (DR3) and HLA-DRB1*1301-DQA1*0103-DQB1*0603 (DR6) haplotypes. Recently, the extended HLA class I region
Primary sclerosing cholangitis (PSC) is associated with the human leukocyte antigen (HLA)-DRB1*0301-DQA1*
Genetic associations in Italian primary sclerosing cholangitis: heterogeneity across Europe defines a critical role for HLA-C.
Hov JR, Lleo A, Selmi C, Woldseth B, Fabris L, Strazzabosco M, Karlsen TH, Invernizzi P. Hov JR, et al. J Hepatol. 2010 May;52(5):712-7. doi: 10.1016/j.jhep.2009.11.029. Epub 2010 Mar 4. J Hepatol. 2010. PMID: 20347497
BACKGROUND & AIMS: The HLA complex on chromosome 6p21 is firmly established as a risk locus for primary sclerosing cholangitis (PSC). ...At HLA-DRB1, we confirmed positive and negative associations with DRB1*15 and DRB1* …
BACKGROUND & AIMS: The HLA complex on chromosome 6p21 is firmly established as a risk locus for primary sclerosing
Novel association of HLA-haplotypes with primary sclerosing cholangitis (PSC) in a southern European population.
Neri TM, Cavestro GM, Seghini P, Zanelli PF, Zanetti A, Savi M, Podda M, Zuin M, Colombo M, Floreani A, Rosina F, Bianchi Porro G, Strazzabosco M, Okolicsanyi L. Neri TM, et al. Dig Liver Dis. 2003 Aug;35(8):571-6. doi: 10.1016/s1590-8658(03)00274-3. Dig Liver Dis. 2003. PMID: 14567462
AIMS: In patients with with primary sclerosing cholangitis we investigated the major histocompatibility complex (MHC) genes and mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. ...DRB1*07, DQA1*0201, DQB1*02 haplotype f …
AIMS: In patients with with primary sclerosing cholangitis we investigated the major histocompatibility complex (MHC) g …
The interleukin-1 and interleukin-10 gene polymorphisms in primary sclerosing cholangitis: no associations with disease susceptibility/resistance.
Donaldson PT, Norris S, Constantini PK, Bernal W, Harrison P, Williams R. Donaldson PT, et al. J Hepatol. 2000 Jun;32(6):882-6. doi: 10.1016/s0168-8278(00)80091-4. J Hepatol. 2000. PMID: 10898307
BACKGROUND/AIMS: Although primary sclerosing cholangitis is believed to be an autoimmune disorder, no tissue-specific auto-antibodies have yet been identified, and the strongest support for an autoimmune aetiology comes from HLA-association studies. .. …
BACKGROUND/AIMS: Although primary sclerosing cholangitis is believed to be an autoimmune disorder, no tissue-specific a …
Human leukocyte antigen-C genes and susceptibility to primary sclerosing cholangitis.
Moloney MM, Thomson LJ, Strettell MJ, Williams R, Donaldson PT. Moloney MM, et al. Hepatology. 1998 Sep;28(3):660-2. doi: 10.1002/hep.510280309. Hepatology. 1998. PMID: 9731555
Genetic susceptibility to primary sclerosing cholangitis (PSC) is associated with the extended HLA A1-B8-DR3 haplotype and also with the DRB3*0101-DRB1*0301-DQA1*0103-DQB1*0603 haplotype. ...These findings indicate that the telomeric limit of …
Genetic susceptibility to primary sclerosing cholangitis (PSC) is associated with the extended HLA A1-B8-DR3 hap …
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