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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1994 1
1995 2
1996 6
1997 6
1998 2
1999 8
2000 4
2001 1
2002 4
2003 6
2004 4
2005 3
2006 4
2007 4
2008 4
2009 4
2010 1
2011 2
2012 4
2013 4
2014 3
2015 7
2016 4
2017 3
2018 5
2019 4
2020 1
2021 1
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96 results
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Page 1
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.
Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy NA, Kupcinskas L, Lawrance IC, Lee JC, Satsangi J, Schreiber S, Théâtre E, van der Meulen-de Jong AE, Weersma RK, Wilson DC; International Inflammatory Bowel Disease Genetics Consortium, Parkes M, Vermeire S, Rioux JD, Mansfield J, Silverberg MS, Radford-Smith G, McGovern DP, Barrett JC, Lees CW. Cleynen I, et al. Lancet. 2016 Jan 9;387(10014):156-67. doi: 10.1016/S0140-6736(15)00465-1. Epub 2015 Oct 18. Lancet. 2016. PMID: 26490195 Free PMC article.
BACKGROUND: Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel disease; treatment strategies have historically been determined by this binary categorisation. ...INTERPRETATION: Our data support a continuum of disorders within inflam …
BACKGROUND: Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel disease; treatment strategies …
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.
Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S; International Inflammatory Bowel Disease Genetics Consortium; Australia and New Zealand IBDGC; Belgium IBD Genetics Consortium; Italian Group for IBD Genetic Consortium; NIDDK Inflammatory Bowel Disease Genetics Consortium; United Kingdom IBDGC; Wellcome Trust Case Control Consortium; Quebec IBD Genetics Consortium, Daly MJ, Van Steen K, Duerr RH, Barrett JC, McGovern DP, Schumm LP, Traherne JA, Carrington MN, Kosmoliaptsis V, Karlsen TH, Franke A, Rioux JD. Goyette P, et al. Nat Genet. 2015 Feb;47(2):172-9. doi: 10.1038/ng.3176. Epub 2015 Jan 5. Nat Genet. 2015. PMID: 25559196 Free PMC article.
To address this, we performed high-density SNP typing of the MHC in >32,000 individuals with IBD, implicating multiple HLA alleles, with a primary role for HLA-DRB1*01:03 in both Crohn's disease and ulcerative colitis. Noteworthy differences …
To address this, we performed high-density SNP typing of the MHC in >32,000 individuals with IBD, implicating multiple HLA alleles …
Association of HLA-DRB1 Alleles with Ulcerative Colitis in the City of Kerman, South Eastern Iran.
Mohammadi M, Rastin M, Rafatpanah H, Abdoli Sereshki H, Zahedi MJ, Nikpoor AR, Baneshi MR, Hayatbakhsh MM. Mohammadi M, et al. Iran J Allergy Asthma Immunol. 2015 Jun;14(3):306-12. Iran J Allergy Asthma Immunol. 2015. PMID: 26546900 Free article.
The association of HLA class II genes with ulcerative colitis (UC) as an autoimmune disease has been investigated for several years. ...This is the novel result that describes an association of HLA-DRB1*13 with UC and also shows the protective r …
The association of HLA class II genes with ulcerative colitis (UC) as an autoimmune disease has been investigated for s …
HLA-DRB1 alleles influence clinical phenotypes in Japanese patients with ulcerative colitis.
Matsumura Y, Kinouchi Y, Nomura E, Negoro K, Kakuta Y, Endo K, Aizawa H, Takagi S, Takahashi S, Shimosegawa T. Matsumura Y, et al. Tissue Antigens. 2008 May;71(5):447-52. doi: 10.1111/j.1399-0039.2008.01031.x. Tissue Antigens. 2008. PMID: 18416774
In Caucasians, HLA-DRB1 has been reported to determine the clinical phenotypes of ulcerative colitis (UC). ...However, the contribution of HLA-DRB1 to the clinical phenotypes in Japanese UC has not been elucidated yet. ...
In Caucasians, HLA-DRB1 has been reported to determine the clinical phenotypes of ulcerative colitis (UC). ...Ho …
Difference in DRB1* gene polymorphisms between Han and Uyghur ulcerative colitis patients in China.
Aheman A, Gao F, Kuerbanjiang A, Li YX, Abuduhadeer M. Aheman A, et al. World J Gastroenterol. 2013 May 7;19(17):2709-13. doi: 10.3748/wjg.v19.i17.2709. World J Gastroenterol. 2013. PMID: 23674880 Free PMC article.
AIM: To evaluate the association between HLA-DRB1 alleles and Han and Uyghur ulcerative colitis (UC) patients residing in the Xinjiang Uyghur Autonomous Region of China. ...HLA-DRB1 alleles showed no association with UC in Han patients. . …
AIM: To evaluate the association between HLA-DRB1 alleles and Han and Uyghur ulcerative colitis (UC) patients re …
HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
Okada Y, Yamazaki K, Umeno J, Takahashi A, Kumasaka N, Ashikawa K, Aoi T, Takazoe M, Matsui T, Hirano A, Matsumoto T, Kamatani N, Nakamura Y, Yamamoto K, Kubo M. Okada Y, et al. Gastroenterology. 2011 Sep;141(3):864-871.e1-5. doi: 10.1053/j.gastro.2011.05.048. Epub 2011 Jul 19. Gastroenterology. 2011. PMID: 21699788
BACKGROUND & AIMS: There are many genetic factors that are associated with both ulcerative colitis (UC) and Crohn's disease (CD). However, genetic factors that have distinct effects on UC and CD have not been examined. ...CONCLUSIONS: The HLA-Cw*1202-B*52 …
BACKGROUND & AIMS: There are many genetic factors that are associated with both ulcerative colitis (UC) and Crohn's diseas …
Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis.
Venkateswaran S, Prince J, Cutler DJ, Marigorta UM, Okou DT, Prahalad S, Mack D, Boyle B, Walters T, Griffiths A, Sauer CG, LeLeiko N, Keljo D, Markowitz J, Baker SS, Rosh J, Pfefferkorn M, Heyman MB, Patel A, Otley A, Baldassano R, Noe J, Rufo P, Oliva-Hemker M, Davis S, Zwick ME, Gibson G, Denson LA, Hyams J, Kugathasan S. Venkateswaran S, et al. Inflamm Bowel Dis. 2018 Mar 19;24(4):829-838. doi: 10.1093/ibd/izx084. Inflamm Bowel Dis. 2018. PMID: 29562276 Free PMC article.
Further conditioning showed independent effects for HLA-DRB1*1301 (OR = 2.25, p = 7.92*10-9) and another SNP rs17188113 (OR = 0.48, p = 7.56*10-9). Two HLA-DRB1 causal alleles are shared with adult onset UC, while at least 2 signals are unique to pedia …
Further conditioning showed independent effects for HLA-DRB1*1301 (OR = 2.25, p = 7.92*10-9) and another SNP rs17188113 (OR = …
Association of HLA-DRB1 alleles and anti-neutrophil cytoplasmic antibodies in Han and Uyghur patients with ulcerative colitis in China.
Gao F, Aheman A, Lu JJ, Abuduhadeer M, Li YX, Kuerbanjiang A. Gao F, et al. J Dig Dis. 2014 Jun;15(6):299-305. doi: 10.1111/1751-2980.12143. J Dig Dis. 2014. PMID: 24597629
OBJECTIVE: We aimed to study the association between HLA-DRB1 alleles and anti-neutrophil cytoplasmic antibodies (ANCA) among Uyghur and Han patients with ulcerative colitis (UC) in China. ...In Uyghur UC patients, HLA-DRB1*13 may be corr …
OBJECTIVE: We aimed to study the association between HLA-DRB1 alleles and anti-neutrophil cytoplasmic antibodies (ANCA) among …
HLA-DRB1 alleles are associated with the clinical course of disease and steroid dependence in Mexican patients with ulcerative colitis.
Yamamoto-Furusho JK, Rodríguez-Bores L, Granados J. Yamamoto-Furusho JK, et al. Colorectal Dis. 2010 Dec;12(12):1231-5. doi: 10.1111/j.1463-1318.2009.02025.x. Colorectal Dis. 2010. PMID: 19674023
AIM: The aim of this study was to study the association between the HLA-DRB1 alleles and the clinical course of ulcerative colitis (UC). ...Significant associations were found between some HLA-DRB1 alleles and the clinical course of disea …
AIM: The aim of this study was to study the association between the HLA-DRB1 alleles and the clinical course of ulcerative
HLA-DRB1*1502 allele, subtype of DR15, is associated with susceptibility to ulcerative colitis and its progression.
Futami S, Aoyama N, Honsako Y, Tamura T, Morimoto S, Nakashima T, Ohmoto A, Okano H, Miyamoto M, Inaba H, et al. Futami S, et al. Dig Dis Sci. 1995 Apr;40(4):814-8. doi: 10.1007/BF02064985. Dig Dis Sci. 1995. PMID: 7720475
HLA-DRB1 allele typing was performed by the PCR-RFLP method on 59 ulcerative colitis (UC) patients and 136 healthy controls. ...DNA typing of HLA-DRB1 revealed that the genotypic frequency of DRB1*1502 was higher in UC than in the
HLA-DRB1 allele typing was performed by the PCR-RFLP method on 59 ulcerative colitis (UC) patients and 136 healt
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