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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1984 1
1991 1
1993 23
1994 47
1995 101
1996 149
1997 181
1998 205
1999 239
2000 282
2001 378
2002 382
2003 437
2004 441
2005 489
2006 578
2007 553
2008 621
2009 617
2010 732
2011 751
2012 803
2013 857
2014 841
2015 924
2016 908
2017 976
2018 991
2019 994
2020 814
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13,727 results
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Page 1
IL-4 and IL-13 Inhibition in Atopic Dermatitis.
Matsunaga MC, Yamauchi PS. Matsunaga MC, et al. J Drugs Dermatol. 2016 Aug 1;15(8):925-9. J Drugs Dermatol. 2016. PMID: 27537991 Review.
The role of the Th2 cytokines, IL-4 and IL-13, in AD has led to the development of biologic agents to treat AD. The aim of this article is to review the role of IL-4 and IL-13 in the pathogenesis of AD and discuss some of the clinical tri …
The role of the Th2 cytokines, IL-4 and IL-13, in AD has led to the development of biologic agents to treat AD. The aim …
Treatment of atopic dermatitis with tralokinumab, an anti-IL-13 mAb.
Wollenberg A, Howell MD, Guttman-Yassky E, Silverberg JI, Kell C, Ranade K, Moate R, van der Merwe R. Wollenberg A, et al. J Allergy Clin Immunol. 2019 Jan;143(1):135-141. doi: 10.1016/j.jaci.2018.05.029. Epub 2018 Jun 12. J Allergy Clin Immunol. 2019. PMID: 29906525 Free article. Clinical Trial.
BACKGROUND: IL-13 has an important role in atopic dermatitis (AD) pathogenesis. Tralokinumab is a fully human mAb that potently and specifically neutralizes IL-13. ...CONCLUSIONS: Tralokinumab treatment was associated with early and sustained improveme …
BACKGROUND: IL-13 has an important role in atopic dermatitis (AD) pathogenesis. Tralokinumab is a fully human mAb that potentl …
The IL-13-OVOL1-FLG axis in atopic dermatitis.
Furue K, Ito T, Tsuji G, Ulzii D, Vu YH, Kido-Nakahara M, Nakahara T, Furue M. Furue K, et al. Immunology. 2019 Dec;158(4):281-286. doi: 10.1111/imm.13120. Epub 2019 Oct 1. Immunology. 2019. PMID: 31509236 Review.
Despite sharing interleukin-4 receptor α (IL-4Rα) in their signaling cascades, IL-4 and IL-13 have different functions in atopic inflammation. IL-13 preferentially participates in the peripheral tissues because tissue-resident grou …
Despite sharing interleukin-4 receptor α (IL-4Rα) in their signaling cascades, IL-4 and IL-13 have differ …
Modulation of the IL-33/IL-13 Axis in Obesity by IL-13Rα2.
Duffen J, Zhang M, Masek-Hammerman K, Nunez A, Brennan A, Jones JEC, Morin J, Nocka K, Kasaian M. Duffen J, et al. J Immunol. 2018 Feb 15;200(4):1347-1359. doi: 10.4049/jimmunol.1701256. Epub 2018 Jan 5. J Immunol. 2018. PMID: 29305434 Free article.
In obesity, IL-13 overcomes insulin resistance by promoting anti-inflammatory macrophage differentiation in adipose tissue. Endogenous IL-13 levels can be modulated by the IL-13 decoy receptor, IL-13Rα2, which inactivates and deple …
In obesity, IL-13 overcomes insulin resistance by promoting anti-inflammatory macrophage differentiation in adipose tissue. En …
Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes.
Junttila IS. Junttila IS. Front Immunol. 2018 Jun 7;9:888. doi: 10.3389/fimmu.2018.00888. eCollection 2018. Front Immunol. 2018. PMID: 29930549 Free PMC article. Review.
Interleukin (IL)-4 and IL-13 are related cytokines that regulate many aspects of allergic inflammation. They play important roles in regulating the responses of lymphocytes, myeloid cells, and non-hematopoietic cells. In T-cells, IL-4 induces th
Interleukin (IL)-4 and IL-13 are related cytokines that regulate many aspects of allergic inflammation. They pla
The evolution of IL-4 and IL-13 and their receptor subunits.
Wang T, Secombes CJ. Wang T, et al. Cytokine. 2015 Sep;75(1):8-13. doi: 10.1016/j.cyto.2015.04.012. Epub 2015 May 21. Cytokine. 2015. PMID: 26005057 Review.
IL-13 promotes in vivo neonatal cardiomyocyte cell cycle activity and heart regeneration.
Wodsedalek DJ, Paddock SJ, Wan TC, Auchampach JA, Kenarsary A, Tsaih SW, Flister MJ, O'Meara CC. Wodsedalek DJ, et al. Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H24-H34. doi: 10.1152/ajpheart.00521.2018. Epub 2018 Oct 19. Am J Physiol Heart Circ Physiol. 2019. PMID: 30339498 Free article.
We have previously demonstrated that IL-13 stimulated cell cycle activity of neonatal CMs in vitro. However, the signaling events that occur downstream of IL-13 in CMs and the role of IL-13 in CM proliferation and regeneration in vivo hav …
We have previously demonstrated that IL-13 stimulated cell cycle activity of neonatal CMs in vitro. However, the signaling eve …
[IL-13].
[No authors listed] [No authors listed] Arerugi. 2017;66(7):955-956. doi: 10.15036/arerugi.66.955. Arerugi. 2017. PMID: 28824037 Japanese. No abstract available.
Targeting IL-13 as a Host-Directed Therapy Against Ulcerative Colitis.
Hoving JC. Hoving JC. Front Cell Infect Microbiol. 2018 Nov 6;8:395. doi: 10.3389/fcimb.2018.00395. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 30460209 Free PMC article. Review.
The role of interleukin-13 in mediating ulcerative colitis remains under scrutiny. Compelling evidence from both man and mouse suggests that IL-13 not only contributes to the pathology associated with disease but is also involved in mediating the infla …
The role of interleukin-13 in mediating ulcerative colitis remains under scrutiny. Compelling evidence from both man and mouse …
IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.
Zhang Y, Li C, Zhang M, Li Z. Zhang Y, et al. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2715-2720. doi: 10.1016/j.bbrc.2018.08.030. Epub 2018 Aug 11. Biochem Biophys Res Commun. 2018. PMID: 30107911
Interleukin 13 and its receptors (IL-13Rs) are correlated with the pathogenesis and progression of various malignances. However, their roles in NKTCL have not been evaluated. ...In vitro, IL-13 activated Stat6 and promoted cell proliferation in
Interleukin 13 and its receptors (IL-13Rs) are correlated with the pathogenesis and progression of various malignances.
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