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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1996 1
2000 3
2001 7
2002 15
2003 8
2004 24
2005 13
2006 21
2007 40
2008 83
2009 130
2010 214
2011 263
2012 285
2013 339
2014 408
2015 398
2016 431
2017 433
2018 465
2019 448
2020 399
2021 2
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3,887 results
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Page 1
IL-17 and IL-22 in immunity: Driving protection and pathology.
Eyerich K, Dimartino V, Cavani A. Eyerich K, et al. Eur J Immunol. 2017 Apr;47(4):607-614. doi: 10.1002/eji.201646723. Eur J Immunol. 2017. PMID: 28295238 Free article. Review.
IL-17 and IL-22 are tissue-signaling cytokines that favor protection and regeneration of barrier organs such as the skin, lung, and gastrointestinal system. ...This review highlights recent understandings in cellular sources, signaling mechanisms, physiologic
IL-17 and IL-22 are tissue-signaling cytokines that favor protection and regeneration of barrier organs such as the ski
IL-22, not simply a Th17 cytokine.
Rutz S, Eidenschenk C, Ouyang W. Rutz S, et al. Immunol Rev. 2013 Mar;252(1):116-32. doi: 10.1111/imr.12027. Immunol Rev. 2013. PMID: 23405899 Review.
Interleukin-22 (IL-22) has important functions in host defense at mucosal surfaces as well as in tissue repair. It is unique as a cytokine that is produced by immune cells, including T-helper (Th) cell subsets and innate lymphocytes, but acts only on n
Interleukin-22 (IL-22) has important functions in host defense at mucosal surfaces as well as in tissue repair.
Clinical importance of IL-22 cascade in IBD.
Mizoguchi A, Yano A, Himuro H, Ezaki Y, Sadanaga T, Mizoguchi E. Mizoguchi A, et al. J Gastroenterol. 2018 Apr;53(4):465-474. doi: 10.1007/s00535-017-1401-7. Epub 2017 Oct 26. J Gastroenterol. 2018. PMID: 29075900 Free PMC article. Review.
IL-22 is a relatively new cytokine that is characterized by several unique biological properties. In the intestines, the effect of IL-22 is restricted mainly to non-lymphoid cells such as epithelial cells. ...This review article discusses how IL
IL-22 is a relatively new cytokine that is characterized by several unique biological properties. In the intestines, the effec
IL-18/IL-18BP and IL-22/IL-22BP: Two interrelated couples with therapeutic potential.
Mühl H, Bachmann M. Mühl H, et al. Cell Signal. 2019 Nov;63:109388. doi: 10.1016/j.cellsig.2019.109388. Epub 2019 Aug 8. Cell Signal. 2019. PMID: 31401146 Free article. Review.
Interleukin (IL)-18 and IL-22 are key components of cytokine networks that play a decisive role in (pathological) inflammation, host defense, and tissue regeneration. ...Herein, we shine a light on the interplay between IL-18 and IL-22
Interleukin (IL)-18 and IL-22 are key components of cytokine networks that play a decisive role in (pathological
Therapeutic opportunities of the IL-22-IL-22R1 system.
Sabat R, Ouyang W, Wolk K. Sabat R, et al. Nat Rev Drug Discov. 2014 Jan;13(1):21-38. doi: 10.1038/nrd4176. Nat Rev Drug Discov. 2014. PMID: 24378801 Review.
Interleukin-22 (IL-22) is a key effector molecule that is produced by activated T cells, including T helper 22 (TH22) cells, TH17 cells and TH1 cells, as well as subsets of innate lymphoid cells. Although IL-22 can act synergistica
Interleukin-22 (IL-22) is a key effector molecule that is produced by activated T cells, including T helper 2
IL-22: There Is a Gap in Our Knowledge.
Zenewicz LA. Zenewicz LA. Immunohorizons. 2018 Jul 5;2(6):198-207. doi: 10.4049/immunohorizons.1800006. Immunohorizons. 2018. PMID: 31022687 Review.
IL-22 is a critical cytokine in modulating tissue responses during inflammation. IL-22 is upregulated in many chronic inflammatory diseases, making IL-22 biology a potentially rewarding therapeutic target. ...In this article, I will highl
IL-22 is a critical cytokine in modulating tissue responses during inflammation. IL-22 is upregulated in many ch
IL-17, IL-21, and IL-22 Cytokines of T Helper 17 Cells in Cancer.
Nalbant A. Nalbant A. J Interferon Cytokine Res. 2019 Jan;39(1):56-60. doi: 10.1089/jir.2018.0057. Epub 2018 Dec 18. J Interferon Cytokine Res. 2019. PMID: 30562123 Review.
Besides IL-17 family cytokines, Th17 cells produce IL-22, IL-21, and IL-26. The dysregulated function of Th17 cells and their cytokines could contribute to pathology of diseases, including cancer. The role of cytokines of Th17 cells such as I
Besides IL-17 family cytokines, Th17 cells produce IL-22, IL-21, and IL-26. The dysregulated function of …
IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression.
Wang Y, Mumm JB, Herbst R, Kolbeck R, Wang Y. Wang Y, et al. J Immunol. 2017 Nov 1;199(9):3316-3325. doi: 10.4049/jimmunol.1700152. Epub 2017 Sep 22. J Immunol. 2017. PMID: 28939759 Free article.
However, little is known about the effects of IL-22 on the regulation of tight junctions in the intestinal epithelium. In this study we report that IL-22 signals exclusively through the basolateral side of polarized Caco-2 cell monolayers. ...Furthermo …
However, little is known about the effects of IL-22 on the regulation of tight junctions in the intestinal epithelium. In this …
Interleukin-22: immunobiology and pathology.
Dudakov JA, Hanash AM, van den Brink MR. Dudakov JA, et al. Annu Rev Immunol. 2015;33:747-85. doi: 10.1146/annurev-immunol-032414-112123. Epub 2015 Feb 11. Annu Rev Immunol. 2015. PMID: 25706098 Free PMC article. Review.
Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs). ...In addition, IL-22 regulates host defense
Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T helper (Th) 17
Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia.
Trevejo-Nunez G, Elsegeiny W, Aggor FEY, Tweedle JL, Kaplan Z, Gandhi P, Castillo P, Ferguson A, Alcorn JF, Chen K, Kolls JK, Gaffen SL. Trevejo-Nunez G, et al. Infect Immun. 2019 Oct 18;87(11):e00550-19. doi: 10.1128/IAI.00550-19. Print 2019 Nov. Infect Immun. 2019. PMID: 31451621 Free PMC article.
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia worldwide, and interleukin-22 (IL-22) helps contain pneumococcal burden in lungs and extrapulmonary tissues. ...The effects of IL-22 can be tempered by a se …
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia worldwide, and interleukin-22 (IL- …
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