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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 4
2004 1
2005 3
2006 3
2007 13
2008 19
2009 39
2010 54
2011 50
2012 46
2013 52
2014 60
2015 70
2016 58
2017 44
2018 57
2019 50
2020 39
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564 results
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Evidence that tissue resident human enthesis γδT-cells can produce IL-17A independently of IL-23R transcript expression.
Cuthbert RJ, Watad A, Fragkakis EM, Dunsmuir R, Loughenbury P, Khan A, Millner PA, Davison A, Marzo-Ortega H, Newton D, Bridgewood C, McGonagle DG. Cuthbert RJ, et al. Ann Rheum Dis. 2019 Nov;78(11):1559-1565. doi: 10.1136/annrheumdis-2019-215210. Epub 2019 Sep 17. Ann Rheum Dis. 2019. PMID: 31530557 Free PMC article.
Entheseal Vδ2 cells expressed high relative abundance of IL-23/17-associated transcripts including IL-23R, RORC and CCR6, whereas the Vδ1 subset almost completely lacked detectable IL-23R transcript. ...CONCLUSION: Spinal entheseal Vδ1 and Vδ2 s …
Entheseal Vδ2 cells expressed high relative abundance of IL-23/17-associated transcripts including IL-23R, RORC and CCR …
IL-23 in inflammatory bowel diseases and colon cancer.
Neurath MF. Neurath MF. Cytokine Growth Factor Rev. 2019 Feb;45:1-8. doi: 10.1016/j.cytogfr.2018.12.002. Epub 2018 Dec 12. Cytokine Growth Factor Rev. 2019. PMID: 30563755 Review.
Genetic studies revealed that subgroups of IBD patients have single nucleotide polymorphisms in the IL-23R gene suggesting that IL-23R signaling affects disease susceptibility. ...Moreover, in several murine models of colitis, suppression of IL- …
Genetic studies revealed that subgroups of IBD patients have single nucleotide polymorphisms in the IL-23R gene suggesting tha …
Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation.
Aden K, Rehman A, Falk-Paulsen M, Secher T, Kuiper J, Tran F, Pfeuffer S, Sheibani-Tezerji R, Breuer A, Luzius A, Jentzsch M, Häsler R, Billmann-Born S, Will O, Lipinski S, Bharti R, Adolph T, Iovanna JL, Kempster SL, Blumberg RS, Schreiber S, Becher B, Chamaillard M, Kaser A, Rosenstiel P. Aden K, et al. Cell Rep. 2016 Aug 23;16(8):2208-2218. doi: 10.1016/j.celrep.2016.07.054. Epub 2016 Aug 11. Cell Rep. 2016. PMID: 27524624 Free PMC article.
Currently, pathogenic actions of IL-23 have been ascribed to specific effects on immune cells. Herein, we unveil a protective role of IL-23R signaling. ...The study identifies a critical barrier-protective immune pathway that originates from, and is orchestra …
Currently, pathogenic actions of IL-23 have been ascribed to specific effects on immune cells. Herein, we unveil a protective role of …
IL-23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice.
Engelbertsen D, Depuydt MAC, Verwilligen RAF, Rattik S, Levinsohn E, Edsfeldt A, Kuperwaser F, Jarolim P, Lichtman AH. Engelbertsen D, et al. J Am Heart Assoc. 2018 Apr 4;7(8):e008257. doi: 10.1161/JAHA.117.008257. J Am Heart Assoc. 2018. PMID: 29618473 Free PMC article.
In this study we investigated the presence of IL-23 receptor (IL-23R)-expressing cells in the atherosclerotic aorta and evaluated the effect of IL-23R deficiency on atherosclerosis development in mice. ...Adoptive transfer of IL-23R
In this study we investigated the presence of IL-23 receptor (IL-23R)-expressing cells in the atherosclerotic aorta and …
ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation.
Fuseini H, Cephus JY, Wu P, Davis JB, Contreras DC, Gandhi VD, Rathmell JC, Newcomb DC. Fuseini H, et al. Front Immunol. 2019 Nov 27;10:2740. doi: 10.3389/fimmu.2019.02740. eCollection 2019. Front Immunol. 2019. PMID: 31849948 Free PMC article.
IL-17A production and IL-23R expression were significantly increased in Th17 cells from WT female mice compared to Th17 cells from WT male mice. Deletion of ERα (Esr1 (-/-)), but not ERβ (Esr2 (-/-)), significantly decreased IL-17A production and IL
IL-17A production and IL-23R expression were significantly increased in Th17 cells from WT female mice compared to Th17
Expression of IL-23R and IL-17 and the pathology and prognosis of urinary bladder carcinoma.
Liu J, Wang L, Wang T, Wang J. Liu J, et al. Oncol Lett. 2018 Oct;16(4):4325-4330. doi: 10.3892/ol.2018.9145. Epub 2018 Jul 13. Oncol Lett. 2018. PMID: 30214568 Free PMC article.
ROC curve was used to detect the diagnostic values of IL-23R and IL-17 protein for UBC. Levels of IL-23R and IL-17 mRNA in UBC tissue were 3.26 and 2.65 times higher than those in adjacent tissue (P<0.05), and serum levels of IL
ROC curve was used to detect the diagnostic values of IL-23R and IL-17 protein for UBC. Levels of IL-23R
IL-23R-activated STAT3/STAT4 is essential for Th1/Th17-mediated CNS autoimmunity.
Lee PW, Smith AJ, Yang Y, Selhorst AJ, Liu Y, Racke MK, Lovett-Racke AE. Lee PW, et al. JCI Insight. 2017 Sep 7;2(17):e91663. doi: 10.1172/jci.insight.91663. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878115 Free PMC article.
IL-6+IL-23 or IL-12+IL-23 generated encephalitogenic T cells and recapitulated the essential cytokine signals provided by antigen-presenting cells, and both IL-6 and IL-12 induced IL-23 receptor expression on both mouse and human n
IL-6+IL-23 or IL-12+IL-23 generated encephalitogenic T cells and recapitulated the essential cytokine signals pr
IL-23R Signaling Plays No Role in Myocardial Infarction.
Engelowski E, Modares NF, Gorressen S, Bouvain P, Semmler D, Alter C, Ding Z, Flögel U, Schrader J, Xu H, Lang PA, Fischer J, Floss DM, Scheller J. Engelowski E, et al. Sci Rep. 2018 Nov 20;8(1):17078. doi: 10.1038/s41598-018-35188-8. Sci Rep. 2018. PMID: 30459442 Free PMC article.
IL-23 is a composite cytokine consisting of p19 and p40 which binds to IL-23R and IL-12Rβ1 to initiate signal transduction characterized by activation of the Jak/STAT, PI3K and Ras/Raf/MAPK pathways. ...Our data showed that IL-23R deficie
IL-23 is a composite cytokine consisting of p19 and p40 which binds to IL-23R and IL-12Rβ1 to initiate signal tr
Combined Effect of IL-12Rβ2 and IL-23R Expression on Prognosis of Patients with Laryngeal Cancer.
Tao Y, Tao T, Gross N, Peng X, Li Y, Huang Z, Liu L, Li G, Chen X, Yang J. Tao Y, et al. Cell Physiol Biochem. 2018;50(3):1041-1054. doi: 10.1159/000494515. Epub 2018 Oct 24. Cell Physiol Biochem. 2018. PMID: 30355949 Free article.
RESULTS: LC tumor cells had a higher IL-12Rβ2 expression and TIL ratio than IL-23R expression and TIL ratio. The significant correlations between IL-12Rβ2 and IL-23R expression and TIL ratios were identified in LC tissues, particularly in …
RESULTS: LC tumor cells had a higher IL-12Rβ2 expression and TIL ratio than IL-23R expression and TIL ratio. The signif …
MiRNA-126 expression inhibits IL-23R mediated TNF-α or IFN-γ production in fibroblast-like synoviocytes in a mice model of collagen-induced rheumatoid arthritis.
Gao J, Kong R, Zhou X, Ji L, Zhang J, Zhao D. Gao J, et al. Apoptosis. 2018 Dec;23(11-12):607-615. doi: 10.1007/s10495-018-1474-7. Apoptosis. 2018. PMID: 30167920 Free PMC article.
Both miR-126 and IL-23R affect rheumatoid arthritis (RA) procession. This study aimed to investigate the association of miR-126 and IL-23R and the possible modulation of miR-126 to RA pathogenesis. ...TNF-α and IFN-γ production and IL-23R
Both miR-126 and IL-23R affect rheumatoid arthritis (RA) procession. This study aimed to investigate the association of miR-12 …
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