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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 2
1991 6
1992 8
1993 7
1994 13
1995 29
1996 20
1997 22
1998 19
1999 21
2000 23
2001 27
2002 41
2003 41
2004 34
2005 61
2006 64
2007 70
2008 89
2009 84
2010 113
2011 127
2012 114
2013 157
2014 179
2015 196
2016 192
2017 221
2018 247
2019 248
2020 213
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2,427 results
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IL-6 as a keystone cytokine in health and disease.
Hunter CA, Jones SA. Hunter CA, et al. Nat Immunol. 2015 May;16(5):448-57. doi: 10.1038/ni.3153. Nat Immunol. 2015. PMID: 25898198 Review.
Interleukin 6 (IL-6) has a broad effect on cells of the immune system and those not of the immune system and often displays hormone-like characteristics that affect homeostatic processes. IL-6 has context-dependent pro- and anti-inflam
Interleukin 6 (IL-6) has a broad effect on cells of the immune system and those not of the immune system and oft
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.
West NR, Hegazy AN, Owens BMJ, Bullers SJ, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, Cieluch C, Rahman N, Müller-Newen G, Owens RJ, Kühl AA, Maloy KJ, Plevy SE; Oxford IBD Cohort Investigators, Keshav S, Travis SPL, Powrie F. West NR, et al. Nat Med. 2017 May;23(5):579-589. doi: 10.1038/nm.4307. Epub 2017 Apr 3. Nat Med. 2017. PMID: 28368383 Free PMC article.
Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are complex chronic inflammatory conditions of the gastrointestinal tract that are driven by perturbed cytokine pathways. ...The OSMR is expressed in
Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are complex chron
YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis.
Zhou X, Li W, Wang S, Zhang P, Wang Q, Xiao J, Zhang C, Zheng X, Xu X, Xue S, Hui L, Ji H, Wei B, Wang H. Zhou X, et al. Cell Rep. 2019 Apr 23;27(4):1176-1189.e5. doi: 10.1016/j.celrep.2019.03.028. Cell Rep. 2019. PMID: 31018132 Free article.
Inflammation, epithelial cell regeneration, macrophage polarization, and gut microbial homeostasis are critical for the pathological processes associated with inflammatory bowel disease (IBD). ...YAP impairs interleukin-4 (IL-4)/IL-13-ind …
Inflammation, epithelial cell regeneration, macrophage polarization, and gut microbial homeostasis are critical for the pathological process …
Inflammatory bowel disease therapy: blockade of cytokines and cytokine signaling pathways.
Yamamoto-Furusho JK. Yamamoto-Furusho JK. Curr Opin Gastroenterol. 2018 Jul;34(4):187-193. doi: 10.1097/MOG.0000000000000444. Curr Opin Gastroenterol. 2018. PMID: 29846261
PURPOSE OF REVIEW: Treatment of inflammatory bowel disease (IBD) patients can vary depending on the degree of response, lack of response or intolerance to conventional or biological agents aimed at blocking various cytokines or integrins. ...RECENT FINDINGS: …
PURPOSE OF REVIEW: Treatment of inflammatory bowel disease (IBD) patients can vary depending on the degree of response, …
Immunotherapy in inflammatory bowel disease: Novel and emerging treatments.
Catalan-Serra I, Brenna Ø. Catalan-Serra I, et al. Hum Vaccin Immunother. 2018;14(11):2597-2611. doi: 10.1080/21645515.2018.1461297. Epub 2018 May 22. Hum Vaccin Immunother. 2018. PMID: 29624476 Free PMC article.
Inflammatory bowel disease (IBD) is a chronic disabling inflammatory process that affects young individuals, with growing incidence. ...In this review we discuss novel therapies targeting alternative pro-inflammatory pathways like IL-12/2
Inflammatory bowel disease (IBD) is a chronic disabling inflammatory process that affects young individuals, wit
Targeting interleukin-6 in inflammatory autoimmune diseases and cancers.
Yao X, Huang J, Zhong H, Shen N, Faggioni R, Fung M, Yao Y. Yao X, et al. Pharmacol Ther. 2014 Feb;141(2):125-39. doi: 10.1016/j.pharmthera.2013.09.004. Epub 2013 Sep 27. Pharmacol Ther. 2014. PMID: 24076269 Review.
Interleukin-6 (IL-6) is a pleiotropic cytokine with significant functions in the regulation of the immune system. As a potent pro-inflammatory cytokine, IL-6 plays a pivotal role in host defense against pathogens and acute stress.
Interleukin-6 (IL-6) is a pleiotropic cytokine with significant functions in the regulation of the immune system
Serum cytokine, chemokine, and growth factor profiles and their modulation in inflammatory bowel disease.
Martinez-Fierro ML, Garza-Veloz I, Rocha-Pizaña MR, Cardenas-Vargas E, Cid-Baez MA, Trejo-Vazquez F, Flores-Morales V, Villela-Ramirez GA, Delgado-Enciso I, Rodriguez-Sanchez IP, Ortiz-Castro Y. Martinez-Fierro ML, et al. Medicine (Baltimore). 2019 Sep;98(38):e17208. doi: 10.1097/MD.0000000000017208. Medicine (Baltimore). 2019. PMID: 31567972 Free PMC article.
Ulcerative colitis (UC) and Crohn disease (CD) are the most common forms of inflammatory bowel disease (IBD). Because these subtypes of IBD are characterized by periods of activity and remission, an understanding of the modulation of biochemical marker …
Ulcerative colitis (UC) and Crohn disease (CD) are the most common forms of inflammatory bowel disease (IBD). Be …
Inflammatory Bowel Disease: Updates on Molecular Targets for Biologics.
Katsanos KH, Papadakis KA. Katsanos KH, et al. Gut Liver. 2017 Jul 15;11(4):455-463. doi: 10.5009/gnl16308. Gut Liver. 2017. PMID: 28486793 Free PMC article. Review.
Therapy for inflammatory bowel disease (IBD) has changed, with several new agents being evaluated. The era of anti-tumor necrosis factor (anti-TNF) antibody therapy saw remarkable progress in IBD therapy. ...The targets of new therapeutic molecules in IBD mus …
Therapy for inflammatory bowel disease (IBD) has changed, with several new agents being evaluated. The era of anti-tumo …
IL-35 recombinant protein reverses inflammatory bowel disease and psoriasis through regulation of inflammatory cytokines and immune cells.
Wang Y, Mao Y, Zhang J, Shi G, Cheng L, Lin Y, Li Y, Zhang X, Zhang Y, Chen X, Deng J, Su X, Dai L, Yang Y, Zhang S, Yu D, Wei Y, Deng H. Wang Y, et al. J Cell Mol Med. 2018 Feb;22(2):1014-1025. doi: 10.1111/jcmm.13428. Epub 2017 Nov 29. J Cell Mol Med. 2018. PMID: 29193791 Free PMC article.
Interleukin-35 (IL-35), a member of the IL-12 family, functions as a new anti-inflammatory factor involved in arthritis, psoriasis, inflammatory bowel disease (IBD) and other immune diseases. ...Further analysis demonstrated
Interleukin-35 (IL-35), a member of the IL-12 family, functions as a new anti-inflammatory factor involved in ar
Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer.
Zhang M, Viennois E, Prasad M, Zhang Y, Wang L, Zhang Z, Han MK, Xiao B, Xu C, Srinivasan S, Merlin D. Zhang M, et al. Biomaterials. 2016 Sep;101:321-40. doi: 10.1016/j.biomaterials.2016.06.018. Epub 2016 Jun 9. Biomaterials. 2016. PMID: 27318094 Free PMC article.
There is a clinical need for new, more effective treatments for chronic and debilitating inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. ...Oral administration of GDNPs 2 increased the survival and proliferation of I …
There is a clinical need for new, more effective treatments for chronic and debilitating inflammatory bowel disease (IB …
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