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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1966 1
1979 1
1983 1
1984 1
1988 2
1989 30
1990 51
1991 72
1992 105
1993 140
1994 153
1995 174
1996 181
1997 178
1998 160
1999 136
2000 160
2001 176
2002 177
2003 187
2004 195
2005 202
2006 232
2007 282
2008 273
2009 329
2010 371
2011 353
2012 370
2013 343
2014 340
2015 350
2016 341
2017 307
2018 306
2019 327
2020 219
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6,652 results
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Page 1
Flip the coin: IL-7 and IL-7R in health and disease.
Barata JT, Durum SK, Seddon B. Barata JT, et al. Nat Immunol. 2019 Dec;20(12):1584-1593. doi: 10.1038/s41590-019-0479-x. Epub 2019 Nov 19. Nat Immunol. 2019. PMID: 31745336 Review.
The cytokine IL-7 and its receptor, IL-7R, are critical for T cell and, in the mouse, B cell development, as well as differentiation and survival of naive T cells, and generation and maintenance of memory T cells. ...We also explore therapeutic implications a …
The cytokine IL-7 and its receptor, IL-7R, are critical for T cell and, in the mouse, B cell development, as well as di …
IL-2, IL-7, and IL-15: Multistage regulators of CD4(+) T helper cell differentiation.
Read KA, Powell MD, McDonald PW, Oestreich KJ. Read KA, et al. Exp Hematol. 2016 Sep;44(9):799-808. doi: 10.1016/j.exphem.2016.06.003. Epub 2016 Jul 15. Exp Hematol. 2016. PMID: 27423815 Review.
Cytokines of the common gamma-chain family, including interleukin (IL)-2, IL-7, and IL-15, have been the subject of intense experimental scrutiny and have well-defined roles as regulators of diverse immune cell types including CD4(+) T helper ce …
Cytokines of the common gamma-chain family, including interleukin (IL)-2, IL-7, and IL-15, have been the …
IL-7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum-infected mice.
Zhu J, Zhang W, Zhang L, Xu L, Chen X, Zhou S, Xu Z, Xiao M, Bai H, Liu F, Su C. Zhu J, et al. J Cell Mol Med. 2018 Jul;22(7):3353-3363. doi: 10.1111/jcmm.13610. Epub 2018 Mar 22. J Cell Mol Med. 2018. PMID: 29566311 Free PMC article.
However, engagement of IL-7 receptor (IL-7R/CD127) on macrophages by S. japonicum infection-induced IL-7 significantly suppressed SEA-triggered macrophage autophagy, which led to an enhanced liver pathology. ...Our study reveals a novel role for …
However, engagement of IL-7 receptor (IL-7R/CD127) on macrophages by S. japonicum infection-induced IL-7
IL-7/IL-7R signaling pathway might play a role in recurrent pregnancy losses by increasing inflammatory Th17 cells and decreasing Treg cells.
Wu L, Li J, Xu HL, Xu B, Tong XH, Kwak-Kim J, Liu YS. Wu L, et al. Am J Reprod Immunol. 2016 Dec;76(6):454-464. doi: 10.1111/aji.12588. Epub 2016 Oct 21. Am J Reprod Immunol. 2016. PMID: 27767237
In decidual stromal cells of women with RPL, increased IL-7 and decreased IL-7R expressions were present when compared to normal controls. ...Regulation of IL-7/IL-7R may be a new therapeutic strategy for RPL....
In decidual stromal cells of women with RPL, increased IL-7 and decreased IL-7R expressions were present when compared …
Interleukin-7 and Immunosenescence.
Nguyen V, Mendelsohn A, Larrick JW. Nguyen V, et al. J Immunol Res. 2017;2017:4807853. doi: 10.1155/2017/4807853. Epub 2017 Apr 6. J Immunol Res. 2017. PMID: 28484723 Free PMC article. Review.
Interleukin-7 (IL-7) plays a central, critical role in the homeostasis of the immune system. Recent studies support a critical role for IL-7 in the maintenance of a vigorous healthspan. ...Perhaps IL-7 might be used to "tune
Interleukin-7 (IL-7) plays a central, critical role in the homeostasis of the immune system. Recent studies supp
Cell circuits between B cell progenitors and IL-7(+) mesenchymal progenitor cells control B cell development.
Fistonich C, Zehentmeier S, Bednarski JJ, Miao R, Schjerven H, Sleckman BP, Pereira JP. Fistonich C, et al. J Exp Med. 2018 Oct 1;215(10):2586-2599. doi: 10.1084/jem.20180778. Epub 2018 Aug 29. J Exp Med. 2018. PMID: 30158115 Free PMC article.
B cell progenitors require paracrine signals such as interleukin-7 (IL-7) provided by bone marrow stromal cells for proliferation and survival. ...Here we show that proB and IL-7(+) cells form a cell circuit wired by IL-7R signalin …
B cell progenitors require paracrine signals such as interleukin-7 (IL-7) provided by bone marrow stromal cells …
El caseinato de sodio incrementa número de linfocitos B en ratones.
Domínguez V, Aguiñiga I, Moreno L, Torres B, Santiago-Osorio E. Domínguez V, et al. Biomedica. 2017 Dec 1;37(4):571-576. doi: 10.7705/biomedica.v37i4.3604. Biomedica. 2017. PMID: 29373776 Free article. Spanish.
Se evidenció, asimismo, el incremento en la concentración de la interleucina 7 (IL-7) en el suero de los ratones tratados con caseinato de sodio, comparados con los que solo recibieron el vehículo (62,1±17,5 Vs. 26,9±4,4 pg/ml).Conclusión. El caseinato de sod …
Se evidenció, asimismo, el incremento en la concentración de la interleucina 7 (IL-7) en el suero de los ratones tratad …
IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex.
Goh TS, Jo Y, Lee B, Kim G, Hwang H, Ko E, Kang SW, Oh SO, Baek SY, Yoon S, Lee JS, Hong C. Goh TS, et al. Mediators Inflamm. 2017;2017:9096829. doi: 10.1155/2017/9096829. Epub 2017 Jan 3. Mediators Inflamm. 2017. PMID: 28127156 Free PMC article.
IL-7 signaling via IL-7Rα and common γ-chain (γc) is necessary for the development and homeostasis of T cells. Although the delicate mechanism in which IL-7Rα downregulation allows the homeostasis of T cell with limited IL-7 has been well
IL-7 signaling via IL-7Rα and common γ-chain (γc) is necessary for the development and homeostasis of T cells. Although
Mechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer Immunotherapy.
Gao J, Zhao L, Wan YY, Zhu B. Gao J, et al. Int J Mol Sci. 2015 May 6;16(5):10267-80. doi: 10.3390/ijms160510267. Int J Mol Sci. 2015. PMID: 25955647 Free PMC article. Review.
Interleukin-7 (IL-7) is a non-hematopoietic cell-derived cytokine with a central role in the adaptive immune system. It promotes lymphocyte development in the thymus and maintains survival of naive and memory T cell homeostasis in the periphery. ...Rec
Interleukin-7 (IL-7) is a non-hematopoietic cell-derived cytokine with a central role in the adaptive immune sys
Recycled IL-7 Can Be Delivered to Neighboring T Cells.
Bazdar DA, Kalinowska M, Panigrahi S, Sieg SF. Bazdar DA, et al. J Immunol. 2015 May 15;194(10):4698-704. doi: 10.4049/jimmunol.1400560. Epub 2015 Apr 13. J Immunol. 2015. PMID: 25870237 Free PMC article.
Our observations indicate that the ability of cells to recycle IL-7 is dependent on IL-7R α-chain (CD127) and endocytosis, consistent with a model whereby IL-7 is internalized via receptor interactions before recycling. These observations provid …
Our observations indicate that the ability of cells to recycle IL-7 is dependent on IL-7R α-chain (CD127) and endocytos …
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