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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 2
1988 23
1989 54
1990 92
1991 147
1992 206
1993 313
1994 419
1995 571
1996 707
1997 894
1998 1096
1999 1527
2000 1858
2001 2213
2002 2507
2003 2817
2004 3210
2005 3588
2006 4016
2007 4294
2008 4554
2009 4865
2010 5298
2011 5715
2012 6167
2013 6720
2014 6807
2015 7348
2016 7107
2017 7720
2018 8338
2019 8417
2020 6342
2021 3
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103,260 results
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Page 1
The nuclear factor NF-kappaB pathway in inflammation.
Lawrence T. Lawrence T. Cold Spring Harb Perspect Biol. 2009 Dec;1(6):a001651. doi: 10.1101/cshperspect.a001651. Epub 2009 Oct 7. Cold Spring Harb Perspect Biol. 2009. PMID: 20457564 Free PMC article. Review.
The nuclear factor NF-kappaB pathway has long been considered a prototypical proinflammatory signaling pathway, largely based on the role of NF-kappaB in the expression of proinflammatory genes including cytokines, chemokines, and adhesion molecules. . …
The nuclear factor NF-kappaB pathway has long been considered a prototypical proinflammatory signaling pathway, largely based …
30 Years of NF-κB: A Blossoming of Relevance to Human Pathobiology.
Zhang Q, Lenardo MJ, Baltimore D. Zhang Q, et al. Cell. 2017 Jan 12;168(1-2):37-57. doi: 10.1016/j.cell.2016.12.012. Epub 2017 Jan 12. Cell. 2017. PMID: 28086098 Free PMC article. Review.
NF-κB was discovered 30 years ago as a rapidly inducible transcription factor. Since that time, it has been found to have a broad role in gene induction in diverse cellular responses, particularly throughout the immune system. ...
NF-κB was discovered 30 years ago as a rapidly inducible transcription factor. Since that time, it has been found to have a broad rol
Introduction to NF-kappaB: players, pathways, perspectives.
Gilmore TD. Gilmore TD. Oncogene. 2006 Oct 30;25(51):6680-4. doi: 10.1038/sj.onc.1209954. Oncogene. 2006. PMID: 17072321 Review.
This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kappaB). It provides an overview of the discovery and current status of NF-kappaB as a research topic. Described are the structures, activities and …
This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kappaB). It provides a …
NF-κB and the link between inflammation and cancer.
DiDonato JA, Mercurio F, Karin M. DiDonato JA, et al. Immunol Rev. 2012 Mar;246(1):379-400. doi: 10.1111/j.1600-065X.2012.01099.x. Immunol Rev. 2012. PMID: 22435567 Review.
Oncogenic activating mutations in NF-κB genes are rare and have been identified only in some lymphoid malignancies, while most NF-κB activating mutations in lymphoid malignancies occur in upstream signaling components that feed into NF-κB. NF-κB activa …
Oncogenic activating mutations in NF-κB genes are rare and have been identified only in some lymphoid malignancies, while most NF
Activators and target genes of Rel/NF-kappaB transcription factors.
Pahl HL. Pahl HL. Oncogene. 1999 Nov 22;18(49):6853-66. doi: 10.1038/sj.onc.1203239. Oncogene. 1999. PMID: 10602461 Free article. Review.
The vertebrate transcription factor NF-kappaB is induced by over 150 different stimuli. Active NF-kappaB, in turn, participates in the control of transcription of over 150 target genes. ...This article contains a complete listing of all NF-ka
The vertebrate transcription factor NF-kappaB is induced by over 150 different stimuli. Active NF-kappaB, in tur …
NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction.
Choi MC, Jo J, Park J, Kang HK, Park Y. Choi MC, et al. Cells. 2019 Jul 17;8(7):734. doi: 10.3390/cells8070734. Cells. 2019. PMID: 31319599 Free PMC article. Review.
The nuclear factor-kappaB (NF-κB) transcription factor has long been recognized as a disease-contributing factor and, thus, has become a therapeutic target for OA. ...In this review, we discuss the roles of NF-κB in OA chondrocytes and related signaling pathw …
The nuclear factor-kappaB (NF-κB) transcription factor has long been recognized as a disease-contributing factor and, thus, ha …
Crosstalk in NF-κB signaling pathways.
Oeckinghaus A, Hayden MS, Ghosh S. Oeckinghaus A, et al. Nat Immunol. 2011 Jul 19;12(8):695-708. doi: 10.1038/ni.2065. Nat Immunol. 2011. PMID: 21772278 Review.
NF-κB transcription factors are critical regulators of immunity, stress responses, apoptosis and differentiation. A variety of stimuli coalesce on NF-κB activation, which can in turn mediate varied transcriptional programs. ...This intricate crosstalk is crucial to
NF-κB transcription factors are critical regulators of immunity, stress responses, apoptosis and differentiation. A variety of stimul
Noncanonical NF-κB Signaling in Health and Disease.
Cildir G, Low KC, Tergaonkar V. Cildir G, et al. Trends Mol Med. 2016 May;22(5):414-429. doi: 10.1016/j.molmed.2016.03.002. Epub 2016 Apr 7. Trends Mol Med. 2016. PMID: 27068135 Review.
Noncanonical NF-κB signaling differs from canonical NF-κB signaling by being activated through different cell surface receptors, cytoplasmic adaptors, and NF-κB dimers. Under normal physiological conditions, this noncanonical pathway has been implicated in di …
Noncanonical NF-κB signaling differs from canonical NF-κB signaling by being activated through different cell surface receptor …
NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer.
Fan Y, Mao R, Yang J. Fan Y, et al. Protein Cell. 2013 Mar;4(3):176-85. doi: 10.1007/s13238-013-2084-3. Epub 2013 Mar 13. Protein Cell. 2013. PMID: 23483479 Free PMC article. Review.
Recently, roles of NF-κB and STAT3 in colon, gastric and liver cancers have been extensively investigated. The activation and interaction between STAT3 and NF-κB play vital roles in control of the communication between cancer cells and inflammatory cells. ...Underst …
Recently, roles of NF-κB and STAT3 in colon, gastric and liver cancers have been extensively investigated. The activation and interac …
NFKB1: a suppressor of inflammation, ageing and cancer.
Cartwright T, Perkins ND, L Wilson C. Cartwright T, et al. FEBS J. 2016 May;283(10):1812-22. doi: 10.1111/febs.13627. Epub 2016 Jan 13. FEBS J. 2016. PMID: 26663363 Free article. Review.
The pleiotropic consequences of nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-κB) pathway activation result from the combinatorial effects of the five subunits that form the homo- and heterodimeric NF-κB complexes. ...Here we d …
The pleiotropic consequences of nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-κB) pathway acti …
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