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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1989 1
1990 1
1991 1
2000 2
2001 27
2002 57
2003 118
2004 147
2005 181
2006 211
2007 234
2008 220
2009 222
2010 252
2011 234
2012 234
2013 239
2014 240
2015 226
2016 227
2017 201
2018 183
2019 172
2020 159
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3,395 results
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Common NOD2/CARD15 variants are not associated with susceptibility or the clinicopathologic characteristics of sporadic colorectal cancer in Hungarian patients.
Lakatos PL, Hitre E, Szalay F, Zinober K, Fuszek P, Lakatos L, Fischer S, Osztovits J, Gemela O, Veres G, Papp J, Ferenci P. Lakatos PL, et al. BMC Cancer. 2007 Mar 27;7:54. doi: 10.1186/1471-2407-7-54. BMC Cancer. 2007. PMID: 17389035 Free PMC article.
Recently, NOD2/CARD15 has been associated with a risk for CRC in some studies, which stemmed from ethnically diverse populations. ...DNA was screened for SNP8, SNP12 and SNP13 NOD2/CARD15 mutations by denaturing-HPLC and confirmed by direct sequencing. …
Recently, NOD2/CARD15 has been associated with a risk for CRC in some studies, which stemmed from ethnically diverse populatio …
NOD2/CARD15 gene polymorphisms and sarcoidosis susceptibility: review and meta-analysis.
Chen X, Zhou Z, Zhang Y, Cheng X, Guo X, Yang X. Chen X, et al. Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(2):115-122. doi: 10.36141/svdld.v35i2.6257. Epub 2018 Apr 28. Sarcoidosis Vasc Diffuse Lung Dis. 2018. PMID: 32476890 Free PMC article. Review.
Background: The association between NOD2/CARD15 (nucleotide binding oligomerisation domain containing 2) gene polymorphisms and susceptibility to sarcoidosis have been extensively investigated in recent years. ...Results: The pooled data showed that the NOD2/ …
Background: The association between NOD2/CARD15 (nucleotide binding oligomerisation domain containing 2) gene polymorphisms an …
NOD2/CARD15 Mutations among Bedouin Arabs with Inflammatory Bowel Disease: Frequency and Phenotype Correlation.
Abu Freha N, Badarna W, Abu Tailakh M, Abu Kaf H, Fich A, Schwartz D, Segal A, Elkrinawi J, Karban A. Abu Freha N, et al. Isr Med Assoc J. 2018 Nov;20(11):695-699. Isr Med Assoc J. 2018. PMID: 30430799 Free article.
NOD2/CARD15 mutations are well-studied in IBD. OBJECTIVES: To investigate the frequency of NOD2/CARD15 mutations in IBD Bedouin patients and their relevance to disease phenotype. ...Blood samples were obtained from all participants who were genotyped f
NOD2/CARD15 mutations are well-studied in IBD. OBJECTIVES: To investigate the frequency of NOD2/CARD15 mutations
NOD2/CARD15 mutations and the risk of reoperation in patients with Crohns disease.
Martínek L, Kupka T, Simova J, Klvaňa P, Bojková M, Uvírová M, Dítě P, Dvorackova J, Hoch J, Zonca P. Martínek L, et al. Rozhl Chir. 2015 Jun;94(6):242-6. Rozhl Chir. 2015. PMID: 26174343
CONCLUSION: NOD2/CARD15 polymorphisms did not significantly affect the reoperation rate. Homozygosity for the 3020insC variant in the NOD2/CARD15 gene is associated with a high risk of reoperation. NOD2/CARD15 gene variants are not signif …
CONCLUSION: NOD2/CARD15 polymorphisms did not significantly affect the reoperation rate. Homozygosity for the 3020insC variant …
Analysis of the NOD2/CARD15 gene in patients affected with the aseptic abscesses syndrome with or without inflammatory bowel disease.
André MF, Aumaître O, Piette JC, Grateau G, Cardoso MC, Ouchchane L, Kémény JL, Dastugue B, Delpech M, Creveaux I. André MF, et al. Dig Dis Sci. 2008 Feb;53(2):490-9. doi: 10.1007/s10620-007-9871-8. Epub 2007 Jun 15. Dig Dis Sci. 2008. PMID: 17570063
We wanted to assess if changes on gene NOD2/CARD15 could contribute to the development of AA in patients with and without IBD. ...CONCLUSIONS: These results suggest that the emergence of AA is not closely related to gene NOD2/CARD15. NOD2/CAR
We wanted to assess if changes on gene NOD2/CARD15 could contribute to the development of AA in patients with and without IBD. …
NOD2/CARD15: relevance in clinical practice.
Vermeire S. Vermeire S. Best Pract Res Clin Gastroenterol. 2004 Jun;18(3):569-75. doi: 10.1016/j.bpg.2003.12.008. Best Pract Res Clin Gastroenterol. 2004. PMID: 15157828 Review.
So far, the relevance of NOD2/CARD15 genotyping for clinical practice is modest. The current data almost unanimously show that NOD2/CARD15 mutations in Crohn's disease are associated with small-bowel involvement. ...If CARD15 variants would pred …
So far, the relevance of NOD2/CARD15 genotyping for clinical practice is modest. The current data almost unanimously show that …
Impact of NOD2/CARD15 polymorphisms on response to monoclonal antibody therapy in Crohn's disease: a systematic review and meta-analysis.
Wang X, Qin L, Cao J, Zhao J. Wang X, et al. Curr Med Res Opin. 2016 Dec;32(12):2007-2012. doi: 10.1080/03007995.2016.1226168. Epub 2016 Sep 16. Curr Med Res Opin. 2016. PMID: 27533749 Review.
The purpose of this study was to perform a meta-analysis to determine the effect of NOD2/CARD15 polymorphisms on treatment response in patients with CD. ...Further studies are necessary to determine the role of NOD2/CARD15 polymorphisms in patients wit …
The purpose of this study was to perform a meta-analysis to determine the effect of NOD2/CARD15 polymorphisms on treatment res …
NOD2/CARD15 gene mutations in patients with gouty arthritis.
Karaarslan A, Kobak S, Berdeli A. Karaarslan A, et al. Bosn J Basic Med Sci. 2016 Nov 10;16(4):276-279. doi: 10.17305/bjbms.2016.1339. Bosn J Basic Med Sci. 2016. PMID: 27357501 Free PMC article.
No correlation between the NOD2/CARD15 variants and clinical or laboratory findings (p > 0.05) was found. The frequencies of the NOD2/CARD15 gene mutations in the patients were similar to healthy control group. No association between clinical or lab …
No correlation between the NOD2/CARD15 variants and clinical or laboratory findings (p > 0.05) was found. The frequencies o …
No impact of NOD2/CARD15 on outcome after SCT.
Sairafi D, Uzunel M, Remberger M, Ringdén O, Mattsson J. Sairafi D, et al. Bone Marrow Transplant. 2008 Jun;41(11):961-4. doi: 10.1038/bmt.2008.9. Epub 2008 Mar 3. Bone Marrow Transplant. 2008. PMID: 18317454 Free article.
Recent studies have pointed towards an association between certain single nucleotide polymorphisms (SNPs) in the NOD2/CARD15 gene, and negative outcome of Allo-SCT. ...On the basis of these findings we conclude that a consideration to NOD2/CARD15 mutat …
Recent studies have pointed towards an association between certain single nucleotide polymorphisms (SNPs) in the NOD2/CARD15 g …
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells.
Hisamatsu T, Suzuki M, Reinecker HC, Nadeau WJ, McCormick BA, Podolsky DK. Hisamatsu T, et al. Gastroenterology. 2003 Apr;124(4):993-1000. doi: 10.1053/gast.2003.50153. Gastroenterology. 2003. PMID: 12671896
Regulation of expression of CARD15/NOD2 by cytokines was determined by Northern blot using the SW480 cell line. Active CARD15/NOD2 protein in SW480 cells was assessed by the combination of immunoprecipitation and immunoblotting using anti-CARD15
Regulation of expression of CARD15/NOD2 by cytokines was determined by Northern blot using the SW480 cell line. Active CARD
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