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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 5
1999 4
2000 6
2001 8
2002 16
2003 27
2004 28
2005 36
2006 32
2007 40
2008 28
2009 19
2010 23
2011 14
2012 16
2013 24
2014 23
2015 19
2016 19
2017 10
2018 7
2019 11
2020 9
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377 results
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[PPARgamma and cancer].
Nakagama H. Nakagama H. Nihon Rinsho. 2010 Feb;68(2):323-9. Nihon Rinsho. 2010. PMID: 20158104 Review. Japanese.
Peroxisome proliferator-activated receptor gamma (PPARgamma) is known to regulate cell growth and differentiation of adipocytes and a variety of tissues, and has been demonstrated to be up regulated in many cancer tissues, including colon and breast ca …
Peroxisome proliferator-activated receptor gamma (PPARgamma) is known to regulate cell growth and differentiation of adipocyte …
KLF4-dependent, PPARgamma-induced expression of GPA33 in colon cancer cell lines.
Rageul J, Mottier S, Jarry A, Shah Y, Théoleyre S, Masson D, Gonzalez FJ, Laboisse CL, Denis MG. Rageul J, et al. Int J Cancer. 2009 Dec 15;125(12):2802-9. doi: 10.1002/ijc.24683. Int J Cancer. 2009. PMID: 19551868 Free PMC article.
The glycoprotein A33 (GPA33) is a colon cancer antigen. Phase I trials with 131I and 125I monoclonal antibody A33 in colon carcinoma patients showed excellent localization to colorectal cancer and some evidence of tumor response. Using DNA microarrays, …
The glycoprotein A33 (GPA33) is a colon cancer antigen. Phase I trials with 131I and 125I monoclonal antibody A33 in colon
Colon cancer: genomics and apoptotic events.
Rupnarain C, Dlamini Z, Naicker S, Bhoola K. Rupnarain C, et al. Biol Chem. 2004 Jun;385(6):449-64. doi: 10.1515/BC.2004.053. Biol Chem. 2004. PMID: 15255176 Review.
Oncogenes and genetic mutations that occur in colon cancer are featured. The molecules and signals that act to eradicate or initiate the apoptosis cascade in cancer cells, are elucidated, and these include caspases, Fas, Bax, Bid, APC, antisense hTERT, PUMA, …
Oncogenes and genetic mutations that occur in colon cancer are featured. The molecules and signals that act to eradicate or in …
Tocopherols and the treatment of colon cancer.
Stone WL, Krishnan K, Campbell SE, Qui M, Whaley SG, Yang H. Stone WL, et al. Ann N Y Acad Sci. 2004 Dec;1031:223-33. doi: 10.1196/annals.1331.022. Ann N Y Acad Sci. 2004. PMID: 15753148 Review.
Colorectal cancer is the second most common cause of cancer deaths in the United States. Vitamin E (VE) and other antioxidants may help prevent colon cancer by decreasing the formation of mutagens arising from the free radical oxidation of fecal lipids …
Colorectal cancer is the second most common cause of cancer deaths in the United States. Vitamin E (VE) and other antioxidants …
Genistein and daidzein induce apoptosis of colon cancer cells by inhibiting the accumulation of lipid droplets.
Liang YS, Qi WT, Guo W, Wang CL, Hu ZB, Li AK. Liang YS, et al. Food Nutr Res. 2018 May 11;62. doi: 10.29219/fnr.v62.1384. eCollection 2018. Food Nutr Res. 2018. PMID: 29849534 Free PMC article.
AIM: The purpose of this study was to investigate the possible mechanisms of genistein (GEN) and daidzein (DAI) in inducing apoptosis of colon cancer cells by inhibition of lipid droplets (LDs) accumulation. ...CONCLUSION: Our results demonstrated that GEN and DAI i …
AIM: The purpose of this study was to investigate the possible mechanisms of genistein (GEN) and daidzein (DAI) in inducing apoptosis of …
Selective activation of PPARgamma in breast, colon, and lung cancer cell lines.
Allred CD, Kilgore MW. Allred CD, et al. Mol Cell Endocrinol. 2005 May 12;235(1-2):21-9. doi: 10.1016/j.mce.2005.02.003. Epub 2005 Mar 16. Mol Cell Endocrinol. 2005. PMID: 15866424
Peroxisome proliferator-activated receptor gamma (PPARgamma) plays a critical albeit poorly defined role in the development and progression of several cancer types including those of the breast, colon, and lung. A PPAR response element (PPRE) re …
Peroxisome proliferator-activated receptor gamma (PPARgamma) plays a critical albeit poorly defined role in the development an …
Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation.
Tylichová Z, Straková N, Vondráček J, Vaculová AH, Kozubík A, Hofmanová J. Tylichová Z, et al. J Nutr Biochem. 2017 Jan;39:145-155. doi: 10.1016/j.jnutbio.2016.09.006. Epub 2016 Sep 28. J Nutr Biochem. 2017. PMID: 27840291
However, the molecular mechanisms of their action in colon cancer cells are still not fully understood. Our study focused on the mechanisms responsible for the diverse effects of sodium butyrate (NaBt), in particular when interacting with docosahexaenoic acid (DHA), …
However, the molecular mechanisms of their action in colon cancer cells are still not fully understood. Our study focused on t …
Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells.
Seetha A, Devaraj H, Sudhandiran G. Seetha A, et al. J Biochem Mol Toxicol. 2020 Feb;34(2):e22433. doi: 10.1002/jbt.22433. Epub 2020 Jan 9. J Biochem Mol Toxicol. 2020. PMID: 31916655
Colorectal cancer (CRC) is the third most common fatal cancer. Indomethacin, a nonsteroidal anti-inflammatory drug, is known to reduce the occurrence of CRC. ...Treatment with juglone was not as effective as with indomethacin; however, a combination of both was show …
Colorectal cancer (CRC) is the third most common fatal cancer. Indomethacin, a nonsteroidal anti-inflammatory drug, is known t …
Differentiation and reversal of malignant changes in colon cancer through PPARgamma.
Sarraf P, Mueller E, Jones D, King FJ, DeAngelo DJ, Partridge JB, Holden SA, Chen LB, Singer S, Fletcher C, Spiegelman BM. Sarraf P, et al. Nat Med. 1998 Sep;4(9):1046-52. doi: 10.1038/2030. Nat Med. 1998. PMID: 9734398
We show here that PPARgamma is expressed at high levels in both well- and poorly-differentiated adenocarcinomas, in normal colonic mucosa and in human colon cancer cell lines. ...These results indicate that the growth and differentiation of colon
We show here that PPARgamma is expressed at high levels in both well- and poorly-differentiated adenocarcinomas, in normal colonic
Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2.
Qiao L, Dai Y, Gu Q, Chan KW, Ma J, Lan HY, Zou B, Rocken C, Ebert MP, Wong BC. Qiao L, et al. Cancer Lett. 2008 Sep 18;268(2):260-71. doi: 10.1016/j.canlet.2008.04.003. Epub 2008 May 13. Cancer Lett. 2008. PMID: 18477501
We investigated whether the anticancer effect of a combination of XIAP down-regulation and PPAR gamma activation on colon cancer is PPARgamma receptor dependent. ...Thus, a combination of XIAP down-regulation and PPARgamma ligands exert a …
We investigated whether the anticancer effect of a combination of XIAP down-regulation and PPAR gamma activation on colon
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