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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 2
2000 2
2001 3
2002 5
2003 7
2004 6
2005 15
2006 15
2007 15
2008 14
2009 9
2010 26
2011 18
2012 22
2013 18
2014 14
2015 18
2016 15
2017 8
2018 19
2019 16
2020 13
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247 results
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Page 1
Nuclear Receptors in the Pathogenesis and Management of Inflammatory Bowel Disease.
Ning L, Lou X, Zhang F, Xu G. Ning L, et al. Mediators Inflamm. 2019 Jan 21;2019:2624941. doi: 10.1155/2019/2624941. eCollection 2019. Mediators Inflamm. 2019. PMID: 30804707 Free PMC article. Review.
Previous epidemiological and genetic studies have documented the association of NRs with the risk of inflammatory bowel disease (IBD). ...As one of the first-line medications for the treatment of IBD, 5-aminosalicylic acid (5-ASA) activates peroxisome prolife …
Previous epidemiological and genetic studies have documented the association of NRs with the risk of inflammatory bowel dis
Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon.
Couch DG, Tasker C, Theophilidou E, Lund JN, O'Sullivan SE. Couch DG, et al. Clin Sci (Lond). 2017 Oct 25;131(21):2611-2626. doi: 10.1042/CS20171288. Print 2017 Nov 1. Clin Sci (Lond). 2017. PMID: 28954820
These effects were explored in acutely and chronically inflamed colon, using inflammatory bowel disease and appendicitis explants. DESIGN: Caco-2 cells and human colonic explants collected from elective bowel cancer, inflammatory bowel
These effects were explored in acutely and chronically inflamed colon, using inflammatory bowel disease and appendiciti …
Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn's disease.
Liu TC, Kern JT, VanDussen KL, Xiong S, Kaiko GE, Wilen CB, Rajala MW, Caruso R, Holtzman MJ, Gao F, McGovern DP, Nunez G, Head RD, Stappenbeck TS. Liu TC, et al. J Clin Invest. 2018 Nov 1;128(11):5110-5122. doi: 10.1172/JCI120453. Epub 2018 Oct 15. J Clin Invest. 2018. PMID: 30137026 Free PMC article.
It is suggested that subtyping of complex inflammatory diseases can be based on genetic susceptibility and relevant environmental exposure (G+E). ...As an example, defective Paneth cells can subtype Crohn's disease (CD) subjects; Paneth cell defects ha …
It is suggested that subtyping of complex inflammatory diseases can be based on genetic susceptibility and relevant environmen …
PPAR-γ with its anti-inflammatory and anti-fibrotic action could be an effective therapeutic target in IBD.
Vetuschi A, Pompili S, Gaudio E, Latella G, Sferra R. Vetuschi A, et al. Eur Rev Med Pharmacol Sci. 2018 Dec;22(24):8839-8848. doi: 10.26355/eurrev_201812_16652. Eur Rev Med Pharmacol Sci. 2018. PMID: 30575926 Free article.
OBJECTIVE: Intestinal fibrosis is a process characterized by an excessive deposition of Extracellular Matrix (ECM) proteins by activated myofibroblasts and represents a consequence of a chronic inflammation that usually occurs during Inflammatory Bowel Disease
OBJECTIVE: Intestinal fibrosis is a process characterized by an excessive deposition of Extracellular Matrix (ECM) proteins by activated myo …
Development, validation and implementation of an in vitro model for the study of metabolic and immune function in normal and inflamed human colonic epithelium.
Pedersen G. Pedersen G. Dan Med J. 2015 Jan;62(1):B4973. Dan Med J. 2015. PMID: 25557335 Review.
Ulcerative colitis (UC) and Crohn's disease (CD), collectively referred to as inflammatory bowel disease (IBD), are chronic immune disorders affecting the gastrointestinal tract. ...It is therefore probable, that studies in models of representat …
Ulcerative colitis (UC) and Crohn's disease (CD), collectively referred to as inflammatory bowel disease
Nuclear Receptors Regulate Intestinal Inflammation in the Context of IBD.
Klepsch V, Moschen AR, Tilg H, Baier G, Hermann-Kleiter N. Klepsch V, et al. Front Immunol. 2019 May 14;10:1070. doi: 10.3389/fimmu.2019.01070. eCollection 2019. Front Immunol. 2019. PMID: 31139192 Free PMC article. Review.
Several NRs are associated with GI pathologies; therefore, systematic analysis of NR biology, the underlying molecular mechanisms, and regulation of target genes can be expected to help greatly in uncovering the course of GI diseases. Recently, an increasing number of NRs …
Several NRs are associated with GI pathologies; therefore, systematic analysis of NR biology, the underlying molecular mechanisms, and regul …
Protective Effect of Naringin on DSS-Induced Ulcerative Colitis in Mice.
Cao H, Liu J, Shen P, Cai J, Han Y, Zhu K, Fu Y, Zhang N, Zhang Z, Cao Y. Cao H, et al. J Agric Food Chem. 2018 Dec 19;66(50):13133-13140. doi: 10.1021/acs.jafc.8b03942. Epub 2018 Dec 4. J Agric Food Chem. 2018. PMID: 30472831
Previous studies have shown the satisfactory anti-inflammatory role of PPARγ in experimental colitis models, mainly through negatively regulating several transcription factors such as nuclear factor-κB (NF-κB). ...We found that naringin significantly relieved DSS-induced …
Previous studies have shown the satisfactory anti-inflammatory role of PPARγ in experimental colitis models, mainly through negativel …
Alliin, a garlic organosulfur compound, ameliorates gut inflammation through MAPK-NF-κB/AP-1/STAT-1 inactivation and PPAR-γ activation.
Shi L, Lin Q, Li X, Nie Y, Sun S, Deng X, Wang L, Lu J, Tang Y, Luo F. Shi L, et al. Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201601013. Epub 2017 Apr 27. Mol Nutr Food Res. 2017. PMID: 28371322
The content of NO, MDA, and MPO, the expression of iNOS and inflammatory factors as well as MAPK and the phosphorylation of PPAR-γ were inhibited in alliin-treated group. ...CONCLUSION: Our results show that alliin ameliorates DSS-induced ulcerative colitis and inhi …
The content of NO, MDA, and MPO, the expression of iNOS and inflammatory factors as well as MAPK and the phosphorylation of PPAR
CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-β-producing macrophages and T cells.
Moreira TG, Horta LS, Gomes-Santos AC, Oliveira RP, Queiroz NMGP, Mangani D, Daniel B, Vieira AT, Liu S, Rodrigues AM, Gomes DA, Gabriely G, Ferreira E, Weiner HL, Rezende RM, Nagy L, Faria AMC. Moreira TG, et al. Mucosal Immunol. 2019 Jan;12(1):188-199. doi: 10.1038/s41385-018-0090-8. Epub 2018 Oct 2. Mucosal Immunol. 2019. PMID: 30279515
We found that CLA-supplemented diet reduced mucosal damage and inflammatory infiltrate in the dextran sodium sulfate (DSS)-induced colitis model. ...Thus, the anti-inflammatory properties of CLA are associated with prevention of colitis but also with development of …
We found that CLA-supplemented diet reduced mucosal damage and inflammatory infiltrate in the dextran sodium sulfate (DSS)-induced co …
Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties.
Smith DG, Martinelli R, Besra GS, Illarionov PA, Szatmari I, Brazda P, Allen MA, Xu W, Wang X, Nagy L, Dowell RD, Rook GAW, Rosa Brunet L, Lowry CA. Smith DG, et al. Psychopharmacology (Berl). 2019 May;236(5):1653-1670. doi: 10.1007/s00213-019-05253-9. Epub 2019 May 22. Psychopharmacology (Berl). 2019. PMID: 31119329 Free PMC article.
Recent studies also demonstrate that immunization with M. vaccae prevents stress-induced exaggeration of proinflammatory cytokine secretion from mesenteric lymph node cells stimulated ex vivo, prevents stress-induced exaggeration of chemically induced colitis in a model of inf
Recent studies also demonstrate that immunization with M. vaccae prevents stress-induced exaggeration of proinflammatory cytokine secretion …
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