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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 7
2001 17
2002 22
2003 37
2004 43
2005 55
2006 63
2007 59
2008 61
2009 78
2010 80
2011 91
2012 83
2013 108
2014 82
2015 88
2016 100
2017 137
2018 98
2019 106
2020 108
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1,359 results
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Page 1
Runx2, an inducer of osteoblast and chondrocyte differentiation.
Komori T. Komori T. Histochem Cell Biol. 2018 Apr;149(4):313-323. doi: 10.1007/s00418-018-1640-6. Epub 2018 Jan 22. Histochem Cell Biol. 2018. PMID: 29356961 Review.
Cbfb stabilizes Runx proteins at different levels among Runx family proteins by inhibiting their ubiquitination-mediated degradation. ...
Cbfb stabilizes Runx proteins at different levels among Runx family proteins by inhibiting their ubiquitination-mediated degra …
The RUNX family: developmental regulators in cancer.
Ito Y, Bae SC, Chuang LS. Ito Y, et al. Nat Rev Cancer. 2015 Feb;15(2):81-95. doi: 10.1038/nrc3877. Epub 2015 Jan 16. Nat Rev Cancer. 2015. PMID: 25592647 Review.
The contextual cues that direct RUNX function represent a fast-growing field in cancer research and could provide insights that are applicable to early cancer detection and treatment. This Review describes how RUNX proteins communicate with key signalling pathways d …
The contextual cues that direct RUNX function represent a fast-growing field in cancer research and could provide insights that are a …
RUNX transcription factors: orchestrators of development.
Mevel R, Draper JE, Lie-A-Ling M, Kouskoff V, Lacaud G. Mevel R, et al. Development. 2019 Sep 5;146(17):dev148296. doi: 10.1242/dev.148296. Development. 2019. PMID: 31488508 Free article. Review.
RUNX transcription factors orchestrate many different aspects of biology, including basic cellular and developmental processes, stem cell biology and tumorigenesis. In this Primer, we introduce the molecular hallmarks of the three mammalian RUNX genes, RUNX1, RUNX2
RUNX transcription factors orchestrate many different aspects of biology, including basic cellular and developmental processes, stem
Roles of Runx2 in Skeletal Development.
Komori T. Komori T. Adv Exp Med Biol. 2017;962:83-93. doi: 10.1007/978-981-10-3233-2_6. Adv Exp Med Biol. 2017. PMID: 28299652 Review.
Cbfb, which is a co-transcription factor for Runx family proteins, plays an important role in skeletal development by stabilizing Runx family proteins. ...Thus, Runx2 is a multifunctional transcription factor that is essential for skeletal development, and Cbfb regu …
Cbfb, which is a co-transcription factor for Runx family proteins, plays an important role in skeletal development by stabilizing …
Expression and Prognosis Analyses of Runt-Related Transcription Factor Family in Human Leukemia.
Sun CC, Li SJ, Chen ZL, Li G, Zhang Q, Li DJ. Sun CC, et al. Mol Ther Oncolytics. 2018 Dec 18;12:103-111. doi: 10.1016/j.omto.2018.12.008. eCollection 2019 Mar 29. Mol Ther Oncolytics. 2018. PMID: 30719500 Free PMC article.
The Runt-related transcription factor (RUNX) family has been reported to participate in diverse human diseases. However, little is known about their expression and prognostic values in human leukemia. ...The mRNA expression levels of the RUNX family in various kinds …
The Runt-related transcription factor (RUNX) family has been reported to participate in diverse human diseases. However, little is kn …
Transcriptional control of T-cell development.
Naito T, Tanaka H, Naoe Y, Taniuchi I. Naito T, et al. Int Immunol. 2011 Nov;23(11):661-8. doi: 10.1093/intimm/dxr078. Epub 2011 Sep 23. Int Immunol. 2011. PMID: 21948191 Review.
Differentiation of T cells into helper versus cytotoxic cells involves not only antagonistic interplay between Runx and T(h) inducing POZ-Kruppel factor (ThPOK) but also complex interactions between MAZR, Gata3 and Myb in the activation and silencing of genes such as Cd4 a …
Differentiation of T cells into helper versus cytotoxic cells involves not only antagonistic interplay between Runx and T(h) inducing …
RUNX in Invertebrates.
Hughes S, Woollard A. Hughes S, et al. Adv Exp Med Biol. 2017;962:3-18. doi: 10.1007/978-981-10-3233-2_1. Adv Exp Med Biol. 2017. PMID: 28299647 Review.
Due to the high degree of functional redundancy amongst vertebrate Runx genes, simpler model organisms with a solo Runx gene, like C. elegans, are invaluable systems in which to probe the molecular basis of RUNX function within a whole organism. Additionally, …
Due to the high degree of functional redundancy amongst vertebrate Runx genes, simpler model organisms with a solo Runx gene, …
Functional relationship between p53 and RUNX proteins.
Bae SC, Kolinjivadi AM, Ito Y. Bae SC, et al. J Mol Cell Biol. 2019 Mar 1;11(3):224-230. doi: 10.1093/jmcb/mjy076. J Mol Cell Biol. 2019. PMID: 30535344 Free PMC article. Review.
RUNX genes belong to a three-membered family of transcription factors, which are well established as master regulators of development. ...Therefore, upon oncogene activation, early inactivation of RUNX genes and subsequent mutation of p53 appear to result in tumour
RUNX genes belong to a three-membered family of transcription factors, which are well established as master regulators of development
Roles of RUNX in Hippo Pathway Signaling.
Passaniti A, Brusgard JL, Qiao Y, Sudol M, Finch-Edmondson M. Passaniti A, et al. Adv Exp Med Biol. 2017;962:435-448. doi: 10.1007/978-981-10-3233-2_26. Adv Exp Med Biol. 2017. PMID: 28299672 Free PMC article. Review.
The Runt-domain (RD) transcription factors (RUNX genes) are an important family of transcriptional mediators that interact with a variety of proteins including the Hippo pathway effector proteins, YAP and TAZ. In this chapter we focus on two examples of RUNX-TAZ/YAP …
The Runt-domain (RD) transcription factors (RUNX genes) are an important family of transcriptional mediators that interact with a var …
Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene.
Kojo S, Yasmin N, Muroi S, Tenno M, Taniuchi I. Kojo S, et al. Nat Commun. 2018 Sep 5;9(1):3593. doi: 10.1038/s41467-018-05803-3. Nat Commun. 2018. PMID: 30185787 Free PMC article.
Notably, Runx complexes suppress these enhancers by distinct mechanisms. Whereas repression of the proximal enhancer depends on the S4 silencer, the maturation enhancer is repressed by Runx in the absence of S4. Moreover, ThPOK, known to antagonize S4-mediated Cd4 r …
Notably, Runx complexes suppress these enhancers by distinct mechanisms. Whereas repression of the proximal enhancer depends on the S …
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