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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 2
1994 15
1995 74
1996 115
1997 141
1998 187
1999 223
2000 255
2001 299
2002 360
2003 454
2004 526
2005 582
2006 715
2007 786
2008 908
2009 1004
2010 1149
2011 1398
2012 1548
2013 1812
2014 1954
2015 2112
2016 2259
2017 2538
2018 2684
2019 2841
2020 2333
2021 2
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26,023 results
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Page 1
The role of STAT3 in autophagy.
You L, Wang Z, Li H, Shou J, Jing Z, Xie J, Sui X, Pan H, Han W. You L, et al. Autophagy. 2015;11(5):729-39. doi: 10.1080/15548627.2015.1017192. Autophagy. 2015. PMID: 25951043 Free PMC article. Review.
Recent reports further indicate that different subcellular localization patterns of STAT3 affect autophagy in various ways. For example, nuclear STAT3 fine-tunes autophagy via the transcriptional regulation of several autophagy-related genes such as BCL2 family memb …
Recent reports further indicate that different subcellular localization patterns of STAT3 affect autophagy in various ways. For examp …
Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
Furtek SL, Backos DS, Matheson CJ, Reigan P. Furtek SL, et al. ACS Chem Biol. 2016 Feb 19;11(2):308-18. doi: 10.1021/acschembio.5b00945. Epub 2016 Jan 15. ACS Chem Biol. 2016. PMID: 26730496 Review.
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that regulates the expression of genes related to cell cycle, cell survival, and immune response associated with cancer progression and malignancy in a number of cance …
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that regulates the expressi …
STAT3 signaling in immunity.
Hillmer EJ, Zhang H, Li HS, Watowich SS. Hillmer EJ, et al. Cytokine Growth Factor Rev. 2016 Oct;31:1-15. doi: 10.1016/j.cytogfr.2016.05.001. Epub 2016 May 9. Cytokine Growth Factor Rev. 2016. PMID: 27185365 Free PMC article. Review.
Mutations in human STAT3 associate with diseases such as immunodeficiency, autoimmunity and cancer. Strikingly, however, either hyperactivation or inactivation of STAT3 results in human disease, indicating tightly regulated STAT3 function is central to health …
Mutations in human STAT3 associate with diseases such as immunodeficiency, autoimmunity and cancer. Strikingly, however, either hyper …
STAT3: a multifaceted oncoprotein.
Guanizo AC, Fernando CD, Garama DJ, Gough DJ. Guanizo AC, et al. Growth Factors. 2018 Apr;36(1-2):1-14. doi: 10.1080/08977194.2018.1473393. Epub 2018 Jun 6. Growth Factors. 2018. PMID: 29873274 Review.
Conversely, augmented STAT3 activity has been reported in as many as 50% of all human tumours. The dogma of STAT3 activity posits that it is a tyrosine phosphorylated transcription factor which modulates the expression of hundreds of genes. However, th …
Conversely, augmented STAT3 activity has been reported in as many as 50% of all human tumours. The dogma of STAT3 activity pos …
The Ying and Yang of STAT3 in Human Disease.
Vogel TP, Milner JD, Cooper MA. Vogel TP, et al. J Clin Immunol. 2015 Oct;35(7):615-23. doi: 10.1007/s10875-015-0187-8. Epub 2015 Aug 18. J Clin Immunol. 2015. PMID: 26280891 Free PMC article. Review.
The transcription factor signal transducer and activator of transcription 3 (STAT3) is a critical regulator of multiple, diverse cellular processes. ...This review summarizes what is known about the role of STAT3 in human disease....
The transcription factor signal transducer and activator of transcription 3 (STAT3) is a critical regulator of m …
STAT1 and STAT3 mutations: important lessons for clinical immunologists.
Olbrich P, Freeman AF. Olbrich P, et al. Expert Rev Clin Immunol. 2018 Dec;14(12):1029-1041. doi: 10.1080/1744666X.2018.1531704. Epub 2018 Oct 25. Expert Rev Clin Immunol. 2018. PMID: 30280610 Review.
The transcription factors signal transducer and activator of transcription (STAT) 1 and STAT3 fulfill fundamental functions in nonimmune and immune cells. ...Expert commentary: The last several years have seen an explosion in the clinical descriptions and pat …
The transcription factors signal transducer and activator of transcription (STAT) 1 and STAT3 fulfill fundamental funct …
The role of STAT3 in leading the crosstalk between human cancers and the immune system.
Wang Y, Shen Y, Wang S, Shen Q, Zhou X. Wang Y, et al. Cancer Lett. 2018 Feb 28;415:117-128. doi: 10.1016/j.canlet.2017.12.003. Epub 2017 Dec 6. Cancer Lett. 2018. PMID: 29222039 Free PMC article. Review.
As a converging point of multiple oncogenic pathways, signal transducer and activator of transcription 3 (STAT3) is constitutively activated both in tumor cells and tumor-infiltrated immune cells. ...Taken together, STAT3 has emerged as a promising target in …
As a converging point of multiple oncogenic pathways, signal transducer and activator of transcription 3 (STAT3) is constituti …
STAT3 Interactors as Potential Therapeutic Targets for Cancer Treatment.
Laudisi F, Cherubini F, Monteleone G, Stolfi C. Laudisi F, et al. Int J Mol Sci. 2018 Jun 16;19(6):1787. doi: 10.3390/ijms19061787. Int J Mol Sci. 2018. PMID: 29914167 Free PMC article. Review.
Signal transducers and activators of transcription (STATs) mediate essential signaling pathways in different biological processes, including immune responses, hematopoiesis, and neurogenesis. ...This makes STAT3 an attractive therapeutic target for cancers. Initial …
Signal transducers and activators of transcription (STATs) mediate essential signaling pathways in different biological processes, in …
STAT3, stem cells, cancer stem cells and p63.
Galoczova M, Coates P, Vojtesek B. Galoczova M, et al. Cell Mol Biol Lett. 2018 Mar 22;23:12. doi: 10.1186/s11658-018-0078-0. eCollection 2018. Cell Mol Biol Lett. 2018. PMID: 29588647 Free PMC article. Review.
Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor with many important functions in the biology of normal and transformed cells. ...Besides other functions, STAT3 is an important regulator of normal stem cells a …
Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor with many important functio …
Highlighted STAT3 as a potential drug target for cancer therapy.
Lee H, Jeong AJ, Ye SK. Lee H, et al. BMB Rep. 2019 Jul;52(7):415-423. doi: 10.5483/BMBRep.2019.52.7.152. BMB Rep. 2019. PMID: 31186087 Free PMC article. Review.
Signal transducer and activator of transcription 3 (STAT3) is a cytoplasmic transcription factor that regulates cell proliferation, differentiation, apoptosis, angiogenesis, inflammation and immune responses. ...So, targeting STAT3 may improve t …
Signal transducer and activator of transcription 3 (STAT3) is a cytoplasmic transcription factor that regulates …
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