Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 2
1968 1
1970 1
1972 1
1974 1
1975 3
1976 5
1977 3
1978 7
1979 2
1980 9
1981 2
1982 11
1983 8
1984 7
1985 12
1986 12
1987 14
1988 31
1989 57
1990 78
1991 127
1992 156
1993 242
1994 417
1995 620
1996 801
1997 1038
1998 1234
1999 1375
2000 1561
2001 1580
2002 1686
2003 1843
2004 1879
2005 2042
2006 2096
2007 2088
2008 2158
2009 2214
2010 2276
2011 2490
2012 2395
2013 2379
2014 2508
2015 2421
2016 2317
2017 2326
2018 2291
2019 2222
2020 1820
2021 2
Text availability
Article attribute
Article type
Publication date

Search Results

46,625 results
Results by year
Filters applied: . Clear all
Page 1
Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease.
Kidd P. Kidd P. Altern Med Rev. 2003 Aug;8(3):223-46. Altern Med Rev. 2003. PMID: 12946237 Free article. Review.
One theory of immune regulation involves homeostasis between T-helper 1 (Th1) and T-helper 2 (Th2) activity. The Th1/Th2 hypothesis arose from 1986 research suggesting mouse T-helper cells expressed differing cytokine patterns. ...Many diseases previously classified …
One theory of immune regulation involves homeostasis between T-helper 1 (Th1) and T-helper 2 (Th2) activity. The Th1/Th2 hypot …
A novel transcription factor, T-bet, directs Th1 lineage commitment.
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. Szabo SJ, et al. Cell. 2000 Mar 17;100(6):655-69. doi: 10.1016/s0092-8674(00)80702-3. Cell. 2000. PMID: 10761931 Free article.
Naive T helper cells differentiate into two subsets, Th1 and Th2, each with distinct functions and cytokine profiles. Here, we report the isolation of T-bet, a Th1-specific T box transcription factor that controls the expression of the hallmark Th1 cytokine, …
Naive T helper cells differentiate into two subsets, Th1 and Th2, each with distinct functions and cytokine profiles. Here, we report …
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.
Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK. Bettelli E, et al. Nature. 2006 May 11;441(7090):235-8. doi: 10.1038/nature04753. Epub 2006 Apr 30. Nature. 2006. PMID: 16648838
Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer.
Tosolini M, Kirilovsky A, Mlecnik B, Fredriksen T, Mauger S, Bindea G, Berger A, Bruneval P, Fridman WH, Pagès F, Galon J. Tosolini M, et al. Cancer Res. 2011 Feb 15;71(4):1263-71. doi: 10.1158/0008-5472.CAN-10-2907. Epub 2011 Feb 8. Cancer Res. 2011. PMID: 21303976 Free article.
Infiltrating cytotoxic T cells, Treg, Th1, and Th17 cells were also quantified in the center and the invasive margin of the tumors. ...Patients with high expression of the Th17 cluster had a poor prognosis, whereas patients with high expression of the Th1 cluster ha …
Infiltrating cytotoxic T cells, Treg, Th1, and Th17 cells were also quantified in the center and the invasive margin of the tumors. . …
Increased plasticity of non-classic Th1 cells toward the Th17 phenotype.
Leipe J, Pirronello F, Klose A, Schulze-Koops H, Skapenko A. Leipe J, et al. Mod Rheumatol. 2020 Sep;30(5):930-936. doi: 10.1080/14397595.2019.1667473. Epub 2019 Oct 17. Mod Rheumatol. 2020. PMID: 31512538
Viable Th1 cells (IFNγ+IL-17-) were sorted into classic Th1 (CD161-CCR6-) and non-classic Th1 (CD161+CCR6+) cells, trans-differentiated under different Th cell-inducing conditions, and assessed for plastic changes by analyzing the Th cell-associated cytokine …
Viable Th1 cells (IFNγ+IL-17-) were sorted into classic Th1 (CD161-CCR6-) and non-classic Th1 (CD161+CCR6+) cells, tran …
Common Features of Regulatory T Cell Specialization During Th1 Responses.
Littringer K, Moresi C, Rakebrandt N, Zhou X, Schorer M, Dolowschiak T, Kirchner F, Rost F, Keller CW, McHugh D, LeibundGut-Landmann S, Robinson MD, Joller N. Littringer K, et al. Front Immunol. 2018 Jun 13;9:1344. doi: 10.3389/fimmu.2018.01344. eCollection 2018. Front Immunol. 2018. PMID: 29951069 Free PMC article.
In the context of Th1 immune responses, co-expression of the Th1 transcription factor T-bet with Foxp3 is essential for Treg cells to control Th1 responses. ...Our analysis defined a set of Th1-specific co-inhibitory receptors and cytotoxic molecules t …
In the context of Th1 immune responses, co-expression of the Th1 transcription factor T-bet with Foxp3 is essential for Treg c …
Association between Th1/Th2 immune imbalance and obesity in women with or without polycystic ovary syndrome.
Gong P, Shi B, Wang J, Cao P, Diao Z, Wang Y, Hu Y, Li S. Gong P, et al. Gynecol Endocrinol. 2018 Aug;34(8):709-714. doi: 10.1080/09513590.2018.1428301. Epub 2018 Feb 15. Gynecol Endocrinol. 2018. PMID: 29447491
OBJECTIVES: This study aimed to investigate the Th1/Th2 cells in peripheral blood of PCOS patients, and assess the potential correlation between Th1/Th2 imbalance and obesity. ...Association between Th1/Th2 imbalance and BMI, WC were evaluated. RESULTS: The p …
OBJECTIVES: This study aimed to investigate the Th1/Th2 cells in peripheral blood of PCOS patients, and assess the potential correlat …
The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.
Amarnath S, Mangus CW, Wang JC, Wei F, He A, Kapoor V, Foley JE, Massey PR, Felizardo TC, Riley JL, Levine BL, June CH, Medin JA, Fowler DH. Amarnath S, et al. Sci Transl Med. 2011 Nov 30;3(111):111ra120. doi: 10.1126/scitranslmed.3003130. Sci Transl Med. 2011. PMID: 22133721 Free PMC article.
Th1 Differentiation Drives the Accumulation of Intravascular, Non-protective CD4 T Cells during Tuberculosis.
Sallin MA, Sakai S, Kauffman KD, Young HA, Zhu J, Barber DL. Sallin MA, et al. Cell Rep. 2017 Mar 28;18(13):3091-3104. doi: 10.1016/j.celrep.2017.03.007. Cell Rep. 2017. PMID: 28355562 Free PMC article.
Recent data indicate that the differentiation state of Th1 cells determines their protective capacity against tuberculosis. Therefore, we examined the role of Th1-polarizing factors in the generation of protective and non-protective subsets of Mtb-specific Th1
Recent data indicate that the differentiation state of Th1 cells determines their protective capacity against tuberculosis. Therefore …
Glutathione and glutathione derivatives in immunotherapy.
Fraternale A, Brundu S, Magnani M. Fraternale A, et al. Biol Chem. 2017 Feb 1;398(2):261-275. doi: 10.1515/hsz-2016-0202. Biol Chem. 2017. PMID: 27514076 Review.
Specifically, GSH depletion in antigen-presenting cells (APCs) correlates with altered antigen processing and reduced secretion of Th1 cytokines. Conversely, an increase in intracellular GSH content stimulates IL-12 and/or IL-27, which in turn induces differentiation of na …
Specifically, GSH depletion in antigen-presenting cells (APCs) correlates with altered antigen processing and reduced secretion of Th1
46,625 results
Jump to page
Feedback