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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 2
1989 1
1992 1
2005 2
2006 32
2007 223
2008 499
2009 829
2010 1118
2011 1460
2012 1528
2013 1627
2014 1766
2015 1896
2016 1892
2017 1901
2018 1883
2019 1881
2020 1486
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17,740 results
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Page 1
The Balance of Th17 versus Treg Cells in Autoimmunity.
Lee GR. Lee GR. Int J Mol Sci. 2018 Mar 3;19(3):730. doi: 10.3390/ijms19030730. Int J Mol Sci. 2018. PMID: 29510522 Free PMC article. Review.
T helper type 17 (Th17) cells and pTreg cells, which share a common precursor cell (the naïve CD4 T cell), require a common tumor growth factor (TGF)-β signal for initial differentiation. However, terminally differentiated cells fulfill opposite functi …
T helper type 17 (Th17) cells and pTreg cells, which share a common precursor cell (the naïve CD4 T cell), require a co …
The pathogenicity of Th17 cells in autoimmune diseases.
Yasuda K, Takeuchi Y, Hirota K. Yasuda K, et al. Semin Immunopathol. 2019 May;41(3):283-297. doi: 10.1007/s00281-019-00733-8. Epub 2019 Mar 19. Semin Immunopathol. 2019. PMID: 30891627 Review.
IL-17-producing T helper (Th17) cells have been implicated in the pathogenesis of many inflammatory and autoimmune diseases. ...Understanding a molecular basis of Th17 differentiation and effector functions is therefore critical for the regulation of the path …
IL-17-producing T helper (Th17) cells have been implicated in the pathogenesis of many inflammatory and autoimmune diseases. . …
Bile acid metabolites control TH17 and Treg cell differentiation.
Hang S, Paik D, Yao L, Kim E, Trinath J, Lu J, Ha S, Nelson BN, Kelly SP, Wu L, Zheng Y, Longman RS, Rastinejad F, Devlin AS, Krout MR, Fischbach MA, Littman DR, Huh JR. Hang S, et al. Nature. 2019 Dec;576(7785):143-148. doi: 10.1038/s41586-019-1785-z. Epub 2019 Nov 27. Nature. 2019. PMID: 31776512 Free PMC article.
Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is unknown whether they affect adaptive immune cells such as T helper cells that express IL-17a (T(H)17 cells) or regulatory T cells (T(reg) cells
Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is unknown whether they affect adaptive …
Th17 Cell Plasticity and Functions in Cancer Immunity.
Guéry L, Hugues S. Guéry L, et al. Biomed Res Int. 2015;2015:314620. doi: 10.1155/2015/314620. Epub 2015 Oct 25. Biomed Res Int. 2015. PMID: 26583099 Free PMC article. Review.
While a role for Th17 cells in promoting inflammation and autoimmune disorders has been extensively and elegantly demonstrated, it is still controversial whether and how Th17 cells influence tumor immunity. ...Th17 cells were consequently …
While a role for Th17 cells in promoting inflammation and autoimmune disorders has been extensively and elegantly demonstrated …
The paradox of Th17 cell functions in tumor immunity.
Asadzadeh Z, Mohammadi H, Safarzadeh E, Hemmatzadeh M, Mahdian-Shakib A, Jadidi-Niaragh F, Azizi G, Baradaran B. Asadzadeh Z, et al. Cell Immunol. 2017 Dec;322:15-25. doi: 10.1016/j.cellimm.2017.10.015. Epub 2017 Oct 31. Cell Immunol. 2017. PMID: 29103586 Review.
Th17 cells increase tumor progression by activating angiogenesis and immunosuppressive activities. They can also mediate antitumor immune responses through recruiting immune cells into tumors, stimulating effector CD8+ T cells, or surprisingly by alter
Th17 cells increase tumor progression by activating angiogenesis and immunosuppressive activities. They can also mediate antit
Th17 Cells and the IL-23/IL-17 Axis in the Pathogenesis of Periodontitis and Immune-Mediated Inflammatory Diseases.
Bunte K, Beikler T. Bunte K, et al. Int J Mol Sci. 2019 Jul 10;20(14):3394. doi: 10.3390/ijms20143394. Int J Mol Sci. 2019. PMID: 31295952 Free PMC article. Review.
Th1 and Th2 cells of the adaptive immune system are the major players in the pathogenesis of IMIDs. In addition, Th17 cells, their key cytokine IL-17, and IL-23 seem to play pivotal roles. This review aims to provide an overview of the current knowledge about …
Th1 and Th2 cells of the adaptive immune system are the major players in the pathogenesis of IMIDs. In addition, Th17 cells
A role for Th1-like Th17 cells in the pathogenesis of inflammatory and autoimmune disorders.
Kamali AN, Noorbakhsh SM, Hamedifar H, Jadidi-Niaragh F, Yazdani R, Bautista JM, Azizi G. Kamali AN, et al. Mol Immunol. 2019 Jan;105:107-115. doi: 10.1016/j.molimm.2018.11.015. Epub 2018 Nov 28. Mol Immunol. 2019. PMID: 30502718 Review.
The T helper 17 (Th17) cells contain a dynamic subset of CD4+ T-cells that are able to develop into other different lineage subsets, including the Th1-like Th17 cells. ...Here, the actual mechanisms for Th17 cells plasticity to Th1 …
The T helper 17 (Th17) cells contain a dynamic subset of CD4+ T-cells that are able to develop into other different lin …
Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans.
Bacher P, Hohnstein T, Beerbaum E, Röcker M, Blango MG, Kaufmann S, Röhmel J, Eschenhagen P, Grehn C, Seidel K, Rickerts V, Lozza L, Stervbo U, Nienen M, Babel N, Milleck J, Assenmacher M, Cornely OA, Ziegler M, Wisplinghoff H, Heine G, Worm M, Siegmund B, Maul J, Creutz P, Tabeling C, Ruwwe-Glösenkamp C, Sander LE, Knosalla C, Brunke S, Hube B, Kniemeyer O, Brakhage AA, Schwarz C, Scheffold A. Bacher P, et al. Cell. 2019 Mar 7;176(6):1340-1355.e15. doi: 10.1016/j.cell.2019.01.041. Epub 2019 Feb 21. Cell. 2019. PMID: 30799037 Free article.
Th17 cells provide protection at barrier tissues but may also contribute to immune pathology. The relevance and induction mechanisms of pathologic Th17 responses in humans are poorly understood. ...Th17 cells directed against other fungi are ind
Th17 cells provide protection at barrier tissues but may also contribute to immune pathology. The relevance and induction mech
The role of transforming growth factor β in T helper 17 differentiation.
Zhang S. Zhang S. Immunology. 2018 Sep;155(1):24-35. doi: 10.1111/imm.12938. Epub 2018 May 8. Immunology. 2018. PMID: 29682722 Free PMC article. Review.
T helper 17 (Th17) cells play critical roles in inflammatory and autoimmune diseases. The lineage-specific transcription factor RORγt is the key regulator for Th17 cell fate commitment. ...TGF-β superfamily members TGF-β(1) , TGF-β(3) or activin A, in concert …
T helper 17 (Th17) cells play critical roles in inflammatory and autoimmune diseases. The lineage-specific transcription facto …
Autoimmune thyroid diseases and Th17/Treg lymphocytes.
Shao S, Yu X, Shen L. Shao S, et al. Life Sci. 2018 Jan 1;192:160-165. doi: 10.1016/j.lfs.2017.11.026. Epub 2017 Nov 20. Life Sci. 2018. PMID: 29158050 Review.
The underlying mechanism comprises inherent genetic predisposition, abnormality of Th17 and Treg related biological molecules, and gut microbiota disorder. New therapeutic strategies have been developed to improve the Th17/Treg equilibrium, including regulation of i …
The underlying mechanism comprises inherent genetic predisposition, abnormality of Th17 and Treg related biological molecules, and gu …
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