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2007 1
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2009 8
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2017 19
2018 16
2019 16
2020 15
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Page 1
Th17 cells in primary Sjögren's syndrome: Pathogenicity and plasticity.
Verstappen GM, Corneth OBJ, Bootsma H, Kroese FGM. Verstappen GM, et al. J Autoimmun. 2018 Feb;87:16-25. doi: 10.1016/j.jaut.2017.11.003. Epub 2017 Nov 27. J Autoimmun. 2018. PMID: 29191572 Free article. Review.
Th17 cells and their signature cytokine IL-17 are also present in salivary gland lesions of primary Sjögren's syndrome (pSS) patients and can be elevated in their peripheral blood. ...Th17 cells can develop towards Th17.1 cells
Th17 cells and their signature cytokine IL-17 are also present in salivary gland lesions of primary Sjögren's syndro
Th17 Cells and the IL-23/IL-17 Axis in the Pathogenesis of Periodontitis and Immune-Mediated Inflammatory Diseases.
Bunte K, Beikler T. Bunte K, et al. Int J Mol Sci. 2019 Jul 10;20(14):3394. doi: 10.3390/ijms20143394. Int J Mol Sci. 2019. PMID: 31295952 Free PMC article. Review.
Th1 and Th2 cells of the adaptive immune system are the major players in the pathogenesis of IMIDs. In addition, Th17 cells, their key cytokine IL-17, and IL-23 seem to play pivotal roles. This review aims to provide an overview of the current knowledge about …
Th1 and Th2 cells of the adaptive immune system are the major players in the pathogenesis of IMIDs. In addition, Th17 cells
Th17/Treg cell level and clinical characteristics of peripheral blood of patients with Sjogren's syndrome complicated with primary biliary cirrhosis.
Hao LR, Li XF, Gao C, Cao L, Han ZY, Gao H. Hao LR, et al. Medicine (Baltimore). 2019 Jun;98(24):e15952. doi: 10.1097/MD.0000000000015952. Medicine (Baltimore). 2019. PMID: 31192933 Free PMC article.
This study aims at analyzing the Th17/Treg cell level and clinical characteristics of the peripheral blood of patients with Sjogren's syndrome (SS) complicated with primary biliary cirrhosis (PBC) so as to deepen the understanding of this disease and s …
This study aims at analyzing the Th17/Treg cell level and clinical characteristics of the peripheral blood of patients with Sjogre
Clinical and immunological parameters of Sjögren's syndrome.
Psianou K, Panagoulias I, Papanastasiou AD, de Lastic AL, Rodi M, Spantidea PI, Degn SE, Georgiou P, Mouzaki A. Psianou K, et al. Autoimmun Rev. 2018 Oct;17(10):1053-1064. doi: 10.1016/j.autrev.2018.05.005. Epub 2018 Aug 10. Autoimmun Rev. 2018. PMID: 30103041 Review.
Sjögren's syndrome (SS) is a chronic autoimmune disease that primarily affects the exocrine glands, resulting in their functional impairment. ...In SS T cells predominate in mild lesions, whereas B cells predominate in advanced lesions. Th1, Th2, Th
Sjögren's syndrome (SS) is a chronic autoimmune disease that primarily affects the exocrine glands, resulting in their functio …
Immune modulation by rebamipide in a mouse model of Sjogren's syndrome via T and B cell regulation.
Jin-Sil P, Sun-Hee H, SeungCheon Y, JeongWon C, Kyung-Ah J, Mi-La C, Sung-Hwan P. Jin-Sil P, et al. Immunol Lett. 2019 Oct;214:1-7. doi: 10.1016/j.imlet.2019.07.005. Epub 2019 Aug 14. Immunol Lett. 2019. PMID: 31421154
It has also been shown to improve dry eye and dry mouth, two major symptoms of Sjogren's syndrome (SS). However, little is known about the effects of rebamipide on T and B cell regulation in SS. ...In vitro, rebamipide suppressed IL-6 and IL-17 production by …
It has also been shown to improve dry eye and dry mouth, two major symptoms of Sjogren's syndrome (SS). However, little …
Unique glandular ex-vivo Th1 and Th17 receptor motifs in Sjögren's syndrome patients using single-cell analysis.
Voigt A, Bohn K, Sukumaran S, Stewart CM, Bhattacharya I, Nguyen CQ. Voigt A, et al. Clin Immunol. 2018 Jul;192:58-67. doi: 10.1016/j.clim.2018.04.009. Epub 2018 Apr 19. Clin Immunol. 2018. PMID: 29679709 Free PMC article.
Primary Sjögren's syndrome (pSS) is an autoimmune disease in which the underlying cause has yet to be elucidated. The main objective of this study was to determine the T cell receptor (TCR) repertoires of individual infiltrating T helper (Th)-1 and 17 cells o …
Primary Sjögren's syndrome (pSS) is an autoimmune disease in which the underlying cause has yet to be elucidated. The main obj …
Ectopic germinal center and megalin defect in primary Sjogren syndrome with renal Fanconi syndrome.
Wang J, Wen Y, Zhou M, Shi X, Jiang L, Li M, Yu Y, Li X, Li X, Zhang W, Lundquist AL, Chen L. Wang J, et al. Arthritis Res Ther. 2017 Jun 2;19(1):120. doi: 10.1186/s13075-017-1317-x. Arthritis Res Ther. 2017. PMID: 28577559 Free PMC article.
BACKGROUND: This study reports the clinical and pathological features of 12 cases of primary Sjogren syndrome (pSS) with renal involvement presenting with proximal tubular dysfunction in a single center, and investigates the possible correlation of ectopic germinal …
BACKGROUND: This study reports the clinical and pathological features of 12 cases of primary Sjogren syndrome (pSS) with renal …
Clinical significance and immunobiology of IL-21 in autoimmunity.
Long D, Chen Y, Wu H, Zhao M, Lu Q. Long D, et al. J Autoimmun. 2019 May;99:1-14. doi: 10.1016/j.jaut.2019.01.013. Epub 2019 Feb 14. J Autoimmun. 2019. PMID: 30773373 Review.
Interleukin-21 (IL-21), an autocrine cytokine predominantly produced by follicular helper T (Tfh) and T helper 17 (Th17) cells, has been proven to play an important role in the immune system, for example, by promoting proliferation and the development of Tfh and …
Interleukin-21 (IL-21), an autocrine cytokine predominantly produced by follicular helper T (Tfh) and T helper 17 (Th17) cells
Short-term and low-dose IL-2 therapy restores the Th17/Treg balance in the peripheral blood of patients with primary Sjögren's syndrome.
Miao M, Hao Z, Guo Y, Zhang X, Zhang S, Luo J, Zhao X, Zhang C, Liu X, Wu X, Xu D, Zhao J, Lu X, Gao C, Li X. Miao M, et al. Ann Rheum Dis. 2018 Dec;77(12):1838-1840. doi: 10.1136/annrheumdis-2018-213036. Epub 2018 Jun 23. Ann Rheum Dis. 2018. PMID: 29936436 No abstract available.
IL-2 Inhibition of Th17 Generation Rather Than Induction of Treg Cells Is Impaired in Primary Sjögren's Syndrome Patients.
Luo J, Ming B, Zhang C, Deng X, Li P, Wei Z, Xia Y, Jiang K, Ye H, Ma W, Liu Z, Li H, Yang XP, Dong L. Luo J, et al. Front Immunol. 2018 Aug 13;9:1755. doi: 10.3389/fimmu.2018.01755. eCollection 2018. Front Immunol. 2018. PMID: 30150979 Free PMC article.
OBJECTIVE: To investigate the role of IL-2 in the balance of Th17 and Tregs and elucidate the underlying mechanisms of enhanced Th17 differentiation in primary Sjögren's syndrome (pSS) patients. ...RESULTS: We found that the percentage of Th17
OBJECTIVE: To investigate the role of IL-2 in the balance of Th17 and Tregs and elucidate the underlying mechanisms of enhanced Th
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