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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 17
2007 107
2008 220
2009 357
2010 399
2011 486
2012 507
2013 558
2014 584
2015 654
2016 637
2017 594
2018 570
2019 545
2020 311
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5,799 results
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Page 1
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Lee JY, Hall JA, Kroehling L, Wu L, Najar T, Nguyen HH, Lin WY, Yeung ST, Silva HM, Li D, Hine A, Loke P, Hudesman D, Martin JC, Kenigsberg E, Merad M, Khanna KM, Littman DR. Lee JY, et al. Cell. 2020 Jan 9;180(1):79-91.e16. doi: 10.1016/j.cell.2019.11.026. Epub 2019 Dec 19. Cell. 2020. PMID: 31866067
Lymphoid cells that produce interleukin (IL)-17 cytokines protect barrier tissues from pathogenic microbes but are also prominent effectors of inflammation and autoimmune disease. ...Using loss- and gain-of-function mouse models, we show that SAA1, SAA2, and …
Lymphoid cells that produce interleukin (IL)-17 cytokines protect barrier tissues from pathogenic microbes but are also prominent eff …
The Balance of Th17 versus Treg Cells in Autoimmunity.
Lee GR. Lee GR. Int J Mol Sci. 2018 Mar 3;19(3):730. doi: 10.3390/ijms19030730. Int J Mol Sci. 2018. PMID: 29510522 Free PMC article. Review.
However, terminally differentiated cells fulfill opposite functions: Th17 cells cause autoimmunity and inflammation, whereas Treg cells inhibit these phenomena and maintain immune homeostasis. ...This review article summarizes recent advances in our un …
However, terminally differentiated cells fulfill opposite functions: Th17 cells cause autoimmunity and inflammation, wh …
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker RA, Muller DN, Hafler DA. Kleinewietfeld M, et al. Nature. 2013 Apr 25;496(7446):518-22. doi: 10.1038/nature11868. Epub 2013 Mar 6. Nature. 2013. PMID: 23467095 Free PMC article.
The newly identified population of interleukin (IL)-17-producing CD4(+) helper T cells (TH17 cells) has a pivotal role in autoimmune diseases. ...Thus, increased dietary salt intake might represent an environmental risk factor for the developmen …
The newly identified population of interleukin (IL)-17-producing CD4(+) helper T cells (TH17 cells) has a pivotal role …
Autoimmune thyroid diseases and Th17/Treg lymphocytes.
Shao S, Yu X, Shen L. Shao S, et al. Life Sci. 2018 Jan 1;192:160-165. doi: 10.1016/j.lfs.2017.11.026. Epub 2017 Nov 20. Life Sci. 2018. PMID: 29158050 Review.
Years of researches have demonstrated that the imbalance of Th17 and Tregs contribute to the thyroid autoimmunity and the severity of autoimmune thyroid disease (AITD). ...New therapeutic strategies have been developed to improve the Th17/Treg equilibr …
Years of researches have demonstrated that the imbalance of Th17 and Tregs contribute to the thyroid autoimmunity and the severity of …
Th17 and regulatory T cell balance in autoimmune and inflammatory diseases.
Noack M, Miossec P. Noack M, et al. Autoimmun Rev. 2014 Jun;13(6):668-77. doi: 10.1016/j.autrev.2013.12.004. Epub 2014 Jan 11. Autoimmun Rev. 2014. PMID: 24418308 Review.
This review focuses on the biology of T helper 17 (Th17) and regulatory T (Treg) cells and their role in inflammatory diseases, such as rheumatoid arthritis. ...These features implicate that the Th17/Treg balance plays a major role in the development a …
This review focuses on the biology of T helper 17 (Th17) and regulatory T (Treg) cells and their role in inflammatory disea
Functional and phenotypic heterogeneity of Th17 cells in health and disease.
Bystrom J, Clanchy FIL, Taher TE, Al-Bogami M, Ong VH, Abraham DJ, Williams RO, Mageed RA. Bystrom J, et al. Eur J Clin Invest. 2019 Jan;49(1):e13032. doi: 10.1111/eci.13032. Epub 2018 Nov 1. Eur J Clin Invest. 2019. PMID: 30289986 Review.
However, Th17 cells also play pro-inflammatory roles in chronic autoimmune diseases. The trigger(s) that initiate these Th17 responses in chronic autoimmune diseases remain unclear. ...Pathogenic bacterial species can change Th1
However, Th17 cells also play pro-inflammatory roles in chronic autoimmune diseases. The trigger(s) that initiat …
The pathogenicity of Th17 cells in autoimmune diseases.
Yasuda K, Takeuchi Y, Hirota K. Yasuda K, et al. Semin Immunopathol. 2019 May;41(3):283-297. doi: 10.1007/s00281-019-00733-8. Epub 2019 Mar 19. Semin Immunopathol. 2019. PMID: 30891627 Review.
IL-17-producing T helper (Th17) cells have been implicated in the pathogenesis of many inflammatory and autoimmune diseases. Targeting the effector cytokines IL-17 and GM-CSF secreted by autoimmune Th17 cells has been shown to be e …
IL-17-producing T helper (Th17) cells have been implicated in the pathogenesis of many inflammatory and autoimmune d
MicroRNA-181c promotes Th17 cell differentiation and mediates experimental autoimmune encephalomyelitis.
Zhang Z, Xue Z, Liu Y, Liu H, Guo X, Li Y, Yang H, Zhang L, Da Y, Yao Z, Zhang R. Zhang Z, et al. Brain Behav Immun. 2018 May;70:305-314. doi: 10.1016/j.bbi.2018.03.011. Epub 2018 Mar 12. Brain Behav Immun. 2018. PMID: 29545117
Among T helper (Th) cell subsets differentiated from naive CD4(+) T cells, IL-17-producing Th17 cells are closely associated with the pathogenesis of autoimmune diseases, including multiple sclerosis (MS) and the MS animal model, experimental …
Among T helper (Th) cell subsets differentiated from naive CD4(+) T cells, IL-17-producing Th17 cells are closely assoc …
A role for Th1-like Th17 cells in the pathogenesis of inflammatory and autoimmune disorders.
Kamali AN, Noorbakhsh SM, Hamedifar H, Jadidi-Niaragh F, Yazdani R, Bautista JM, Azizi G. Kamali AN, et al. Mol Immunol. 2019 Jan;105:107-115. doi: 10.1016/j.molimm.2018.11.015. Epub 2018 Nov 28. Mol Immunol. 2019. PMID: 30502718 Review.
Recent reports have shown that Th1-like Th17 cells play crucial roles in the pathogenesis of autoimmune diseases such as inflammatory bowel disease, multiple sclerosis and rheumatoid arthritis, as well as, some primary immunodeficiency with a
Recent reports have shown that Th1-like Th17 cells play crucial roles in the pathogenesis of autoimmune diseases
Th17 Cells and the IL-23/IL-17 Axis in the Pathogenesis of Periodontitis and Immune-Mediated Inflammatory Diseases.
Bunte K, Beikler T. Bunte K, et al. Int J Mol Sci. 2019 Jul 10;20(14):3394. doi: 10.3390/ijms20143394. Int J Mol Sci. 2019. PMID: 31295952 Free PMC article. Review.
Th1 and Th2 cells of the adaptive immune system are the major players in the pathogenesis of IMIDs. In addition, Th17 cells, their key cytokine IL-17, and IL-23 seem to play pivotal roles. This review aims to provide an overview of the current knowledge about …
Th1 and Th2 cells of the adaptive immune system are the major players in the pathogenesis of IMIDs. In addition, Th17 cells
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