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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1941 1
1943 4
1944 1
1945 5
1946 34
1947 36
1948 57
1949 59
1950 57
1951 86
1952 93
1953 101
1954 87
1955 100
1956 90
1957 80
1958 80
1959 88
1960 105
1961 131
1962 185
1963 533
1964 739
1965 571
1966 626
1967 863
1968 955
1969 1052
1970 1120
1971 1266
1972 1308
1973 1346
1974 1440
1975 1322
1976 1177
1977 1203
1978 1028
1979 1135
1980 1080
1981 1032
1982 1121
1983 1141
1984 1258
1985 1304
1986 1235
1987 1304
1988 1401
1989 1547
1990 1650
1991 1620
1992 1643
1993 1643
1994 1647
1995 1584
1996 1570
1997 1592
1998 1594
1999 1484
2000 1612
2001 1519
2002 1636
2003 1775
2004 1743
2005 1943
2006 2091
2007 2122
2008 2297
2009 2295
2010 2555
2011 2752
2012 2982
2013 3177
2014 3137
2015 3076
2016 3095
2017 3158
2018 3250
2019 3354
2020 2730
2021 2
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93,776 results
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Page 1
Alkaline Phosphatase: Discovery and Naming of Our Favorite Enzyme.
Siller AF, Whyte MP. Siller AF, et al. J Bone Miner Res. 2018 Feb;33(2):362-364. doi: 10.1002/jbmr.3225. Epub 2017 Aug 14. J Bone Miner Res. 2018. PMID: 28727174 Free article.
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. ...The term alkaline phosphatase emerged when it became necessary to distinguish "b
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bo
Pediatric reference intervals for alkaline phosphatase.
Zierk J, Arzideh F, Haeckel R, Cario H, Frühwald MC, Groß HJ, Gscheidmeier T, Hoffmann R, Krebs A, Lichtinghagen R, Neumann M, Ruf HG, Steigerwald U, Streichert T, Rascher W, Metzler M, Rauh M. Zierk J, et al. Clin Chem Lab Med. 2017 Jan 1;55(1):102-110. doi: 10.1515/cclm-2016-0318. Clin Chem Lab Med. 2017. PMID: 27505090 Free article.
BACKGROUND: Interpretation of alkaline phosphatase activity in children is challenging due to extensive changes with growth and puberty leading to distinct sex- and age-specific dynamics. ...Measurement of alkaline phosphatase activity was performed on …
BACKGROUND: Interpretation of alkaline phosphatase activity in children is challenging due to extensive changes with growth an …
Alkaline phosphatase activity - pH impact on the measurement result.
Grote-Koska D, Klauke R, Brand K, Schumann G. Grote-Koska D, et al. Clin Chem Lab Med. 2017 Jun 27;55(7):e146-e149. doi: 10.1515/cclm-2016-0771. Clin Chem Lab Med. 2017. PMID: 27845880 No abstract available.
Alkaline phosphatase.
Kaplan MM. Kaplan MM. Gastroenterology. 1972 Mar;62(3):452-68. Gastroenterology. 1972. PMID: 4551808 Review. No abstract available.
Recent advances in intestinal alkaline phosphatase, inflammation, and nutrition.
Lallès JP. Lallès JP. Nutr Rev. 2019 Oct 1;77(10):710-724. doi: 10.1093/nutrit/nuz015. Nutr Rev. 2019. PMID: 31086953 Review.
In recent years, much new data on intestinal alkaline phosphatase (IAP) have been published, and major breakthroughs have been disclosed. ...Many recent papers have also explored the prophylactic and therapeutic potential of IAP and other alkaline phosphat
In recent years, much new data on intestinal alkaline phosphatase (IAP) have been published, and major breakthroughs have been …
Inhibition of alkaline phosphatase: an emerging new drug target.
al-Rashida M, Iqbal J. al-Rashida M, et al. Mini Rev Med Chem. 2015;15(1):41-51. doi: 10.2174/1389557515666150219113205. Mini Rev Med Chem. 2015. PMID: 25694083 Review.
Alkaline phosphatase (AP, EC 3.1.3.1.) is a metalloenzyme that belongs to a family of ectonucleotidases. The other members of ectonucleotidase family are ecto-nucleoside triphosphate diphosphohydrolases (E-NTPDases), ecto-nucleotide pyrophosphatase/phosphodiesterase
Alkaline phosphatase (AP, EC 3.1.3.1.) is a metalloenzyme that belongs to a family of ectonucleotidases. The other members of
Serum alkaline phosphatase (AP) is perhaps the most widely used biomarker since it was discovered. Introduction.
[No authors listed] [No authors listed] Subcell Biochem. 2015;76:v-vii. Subcell Biochem. 2015. PMID: 26410897 No abstract available.
Ontogeny of alkaline phosphatase activity in infant intestines and breast milk.
Yang Y, Rader E, Peters-Carr M, Bent RC, Smilowitz JT, Guillemin K, Rader B. Yang Y, et al. BMC Pediatr. 2019 Jan 3;19(1):2. doi: 10.1186/s12887-018-1379-1. BMC Pediatr. 2019. PMID: 30606146 Free PMC article.
The metalloenzyme alkaline phosphatase (ALP) has been shown to reduce lipopolysaccharide-mediated inflammation. Additionally, premature rat pups have reduced alkaline phosphatase activity and expression as compared to full term pups. ...Breast milk …
The metalloenzyme alkaline phosphatase (ALP) has been shown to reduce lipopolysaccharide-mediated inflammation. Additionally, …
Tissue Non-Specific Alkaline Phosphatase and Vascular Calcification: A Potential Therapeutic Target.
Azpiazu D, Gonzalo S, Villa-Bellosta R. Azpiazu D, et al. Curr Cardiol Rev. 2019;15(2):91-95. doi: 10.2174/1573403X14666181031141226. Curr Cardiol Rev. 2019. PMID: 30381085 Free PMC article. Review.
Extracellular pyrophosphate can be synthesized from extracellular ATP by ecto-nucleotide pyrophosphatase/ phosphodiesterase, whereas pyrophosphate is hydrolyzed to phosphate by tissuenonspecific alkaline phosphatase, contributing to the formation of hydroxyapatite c …
Extracellular pyrophosphate can be synthesized from extracellular ATP by ecto-nucleotide pyrophosphatase/ phosphodiesterase, whereas pyropho …
An alkaline phosphatase transport mechanism in the pathogenesis of Alzheimer's disease and neurodegeneration.
Pike AF, Kramer NI, Blaauboer BJ, Seinen W, Brands R. Pike AF, et al. Chem Biol Interact. 2015 Jan 25;226:30-9. doi: 10.1016/j.cbi.2014.12.006. Epub 2014 Dec 11. Chem Biol Interact. 2015. PMID: 25500268 Review.
In this mechanism, a switch in the role of alkaline phosphatase from its baseline duties to a stopgap anti-inflammatory function results in the loss of alkaline phosphatase from cell membranes into circulation, thereby decreasing blood-brain barrier in …
In this mechanism, a switch in the role of alkaline phosphatase from its baseline duties to a stopgap anti-inflammatory functi …
93,776 results
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