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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 2
1958 1
1960 2
1961 1
1963 1
1964 2
1966 1
1967 1
1968 1
1969 2
1970 2
1972 2
1974 1
1975 4
1976 1
1977 1
1979 3
1980 4
1981 2
1982 5
1983 4
1984 2
1985 2
1986 6
1987 5
1988 8
1989 10
1990 10
1991 7
1992 14
1993 10
1994 14
1995 14
1996 13
1997 14
1998 11
1999 8
2000 21
2001 11
2002 17
2003 20
2004 11
2005 15
2006 25
2007 29
2008 41
2009 31
2010 31
2011 50
2012 40
2013 38
2014 33
2015 46
2016 31
2017 45
2018 41
2019 30
2020 8
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728 results
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Page 1
Common Bile Duct Ligation as Model for Secondary Biliary Cirrhosis.
Van Campenhout S, Van Vlierberghe H, Devisscher L. Van Campenhout S, et al. Methods Mol Biol. 2019;1981:237-247. doi: 10.1007/978-1-4939-9420-5_15. Methods Mol Biol. 2019. PMID: 31016658
Cholestatic liver disease can be mild but generally progresses to more severe conditions with increased hepatobiliary injury, cholangitis, and ultimately liver fibrosis and cirrhosis. An extensively used experimental model to investigate the pathophysi …
Cholestatic liver disease can be mild but generally progresses to more severe conditions with increased hepatobiliary injury, cholang …
Etiopathogenesis of autoimmune hepatitis.
Floreani A, Restrepo-Jiménez P, Secchi MF, De Martin S, Leung PSC, Krawitt E, Bowlus CL, Gershwin ME, Anaya JM. Floreani A, et al. J Autoimmun. 2018 Dec;95:133-143. doi: 10.1016/j.jaut.2018.10.020. Epub 2018 Oct 29. J Autoimmun. 2018. PMID: 30385083 Review.
Autoimmune hepatitis is a chronic inflammatory liver disease characterized by hypergammaglobulinemia, the presence of autoantibodies, and inflammation within the liver, including lymphocytic infiltrates and interface hepatitis. ...Herein we present a review of the e …
Autoimmune hepatitis is a chronic inflammatory liver disease characterized by hypergammaglobulinemia, the presence of autoantibodies, …
Environmental basis of primary biliary cholangitis.
Tanaka A, Leung PS, Gershwin ME. Tanaka A, et al. Exp Biol Med (Maywood). 2018 Jan;243(2):184-189. doi: 10.1177/1535370217748893. Epub 2018 Jan 7. Exp Biol Med (Maywood). 2018. PMID: 29307284 Free PMC article. Review.
Primary biliary cholangitis, formally known as primary biliary cirrhosis, is considered a model autoimmune disease for which our group has extensively evaluated environmental factors involved in its etiology. ...The link between xenobiotics and PBC has …
Primary biliary cholangitis, formally known as primary biliary cirrhosis, is considered a model autoimmune disea …
Animal models of primary biliary cirrhosis.
Katsumi T, Tomita K, Leung PS, Yang GX, Gershwin ME, Ueno Y. Katsumi T, et al. Clin Rev Allergy Immunol. 2015 Jun;48(2-3):142-53. doi: 10.1007/s12016-015-8482-y. Clin Rev Allergy Immunol. 2015. PMID: 25771770 Review.
Primary biliary cirrhosis (PBC) is characterized histologically by the presence of chronic non-suppurative destructive cholangitis of the small interlobular bile duct, leading to chronic progressive cholestasis. ...Therefore, the use of an animal model
Primary biliary cirrhosis (PBC) is characterized histologically by the presence of chronic non-suppurative destructive cholang …
Experimental models of liver fibrosis.
Yanguas SC, Cogliati B, Willebrords J, Maes M, Colle I, van den Bossche B, de Oliveira CPMS, Andraus W, Alves VAF, Leclercq I, Vinken M. Yanguas SC, et al. Arch Toxicol. 2016 May;90(5):1025-1048. doi: 10.1007/s00204-015-1543-4. Epub 2015 Jun 6. Arch Toxicol. 2016. PMID: 26047667 Free PMC article. Review.
Liver fibrosis can progress into more severe stages, known as cirrhosis, when liver acini are substituted by nodules, and further to hepatocellular carcinoma. ...The present paper provides a state-of-the-art overview of in vivo and in vitro models used
Liver fibrosis can progress into more severe stages, known as cirrhosis, when liver acini are substituted by nodules, a
Metabolomic analysis of cholestatic liver damage in mice.
Yang R, Zhao Q, Hu DD, Xiao XR, Huang JF, Li F. Yang R, et al. Food Chem Toxicol. 2018 Oct;120:253-260. doi: 10.1016/j.fct.2018.07.022. Epub 2018 Jul 20. Food Chem Toxicol. 2018. PMID: 30009888
Cholestasis is characterized by the obstruction of bile duct, including primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). ...But, the liver glutathione was decreased in DDC induced extrahepatic PSC. The level of plasma phospholipids wa …
Cholestasis is characterized by the obstruction of bile duct, including primary biliary cirrhosis (PBC) and primary sclerosing …
Animal models in primary biliary cirrhosis and primary sclerosing cholangitis.
Pollheimer MJ, Fickert P. Pollheimer MJ, et al. Clin Rev Allergy Immunol. 2015 Jun;48(2-3):207-17. doi: 10.1007/s12016-014-8442-y. Clin Rev Allergy Immunol. 2015. PMID: 25172178 Review.
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are immune-mediated cholangiopathies with enigmatic etiology and pathogenesis. ...Potential cholangiopathy animal models should be systematically investigated in regard to elevate …
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are immune-mediated cholangiopathies with enigmatic e …
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration.
Ferreira-Gonzalez S, Lu WY, Raven A, Dwyer B, Man TY, O'Duibhir E, Lewis PJS, Campana L, Kendall TJ, Bird TG, Tarrats N, Acosta JC, Boulter L, Forbes SJ. Ferreira-Gonzalez S, et al. Nat Commun. 2018 Mar 9;9(1):1020. doi: 10.1038/s41467-018-03299-5. Nat Commun. 2018. PMID: 29523787 Free PMC article.
We have developed a mouse model of biliary senescence, based on the conditional deletion of Mdm2 in bile ducts under the control of the Krt19 promoter, that exhibits features of biliary disease. ...Finally, we study how inhibition of TGFβ-signalling disrupts …
We have developed a mouse model of biliary senescence, based on the conditional deletion of Mdm2 in bile ducts under the contr …
The immunobiology of female predominance in primary biliary cholangitis.
Gerussi A, Cristoferi L, Carbone M, Asselta R, Invernizzi P. Gerussi A, et al. J Autoimmun. 2018 Dec;95:124-132. doi: 10.1016/j.jaut.2018.10.015. Epub 2018 Oct 25. J Autoimmun. 2018. PMID: 30509386 Review.
Primary biliary cholangitis (PBC) is an autoimmune liver disease with a striking female preponderance. The mechanisms behind this predominance are still to be elucidated, although multiple theories have been postulated and investigated. ...More recently, a novel mic …
Primary biliary cholangitis (PBC) is an autoimmune liver disease with a striking female preponderance. The mechanisms behind t …
Activation of TRPV1 receptors affects memory function and hippocampal TRPV1 and CREB mRNA expression in a rat model of biliary cirrhosis.
Bashiri H, Hosseini-Chegeni H, Alsadat Sharifi K, Sahebgharani M, Salari AA. Bashiri H, et al. Neurol Res. 2018 Nov;40(11):938-947. doi: 10.1080/01616412.2018.1504158. Epub 2018 Aug 6. Neurol Res. 2018. PMID: 30079821
OBJECTIVE: Memory impairment induced by biliary cirrhosis is associated with abnormalities in the function of different neurotransmitter systems. However, the exact molecular mechanisms involved in the learning and memory dysfunctions following biliary cir
OBJECTIVE: Memory impairment induced by biliary cirrhosis is associated with abnormalities in the function of different neurot …
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