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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1979 1
1981 1
1982 2
1983 2
1984 2
1985 6
1986 5
1987 2
1988 2
1989 7
1990 5
1991 4
1992 1
1993 4
1994 7
1995 6
1996 8
1997 4
1998 4
1999 2
2000 6
2001 2
2002 6
2003 9
2004 4
2005 5
2006 6
2007 9
2008 9
2009 9
2010 7
2011 6
2012 9
2013 6
2014 9
2015 6
2016 2
2017 9
2018 7
2019 5
2020 5
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200 results
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Page 1
Symptoms of PBC - Pathophysiology and management.
Khanna A, Leighton J, Lee Wong L, Jones DE. Khanna A, et al. Best Pract Res Clin Gastroenterol. 2018 Jun-Aug;34-35:41-47. doi: 10.1016/j.bpg.2018.06.007. Epub 2018 Jun 14. Best Pract Res Clin Gastroenterol. 2018. PMID: 30343709 Review.
Though up to fifty percent of the patients can be asymptomatic at presentation, symptoms when present are frequently debilitating with significant impact on quality of life and functional status. ...With the exception of pruritus, the "classic" cholestatic symptom, therape …
Though up to fifty percent of the patients can be asymptomatic at presentation, symptoms when present are frequently debilitating wit …
[Autoimmune hepatitis: Immunological diagnosis].
Brahim I, Brahim I, Hazime R, Admou B. Brahim I, et al. Presse Med. 2017 Nov;46(11):1008-1019. doi: 10.1016/j.lpm.2017.08.012. Epub 2017 Sep 14. Presse Med. 2017. PMID: 28919271 Review. French.
AIHT have a wide spectrum of presentation, ranging from asymptomatic forms to severe acute liver failure. The diagnosis of AIHT is based on the presence of hyperglobulinemia, cytolysis, cholestasis, typical even specific circulating auto-antibodies, distinctive of AIH or …
AIHT have a wide spectrum of presentation, ranging from asymptomatic forms to severe acute liver failure. The diagnosis of AIHT is ba …
Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus.
Hegade VS, Pechlivanis A, McDonald JAK, Rees D, Corrigan M, Hirschfield GM, Taylor-Robinson SD, Holmes E, Marchesi JR, Kendrick S, Jones DE. Hegade VS, et al. Liver Int. 2019 May;39(5):967-975. doi: 10.1111/liv.14069. Epub 2019 Feb 25. Liver Int. 2019. PMID: 30735608 Free article.
Control group included 31 asymptomatic PBC patients and 18 healthy volunteers. BA profiling was done by ultra performance liquid chromatography coupled to a mass spectrometry (UPLC-MS). ...RESULTS: In PBC patients with pruritus, serum levels of total and glyc …
Control group included 31 asymptomatic PBC patients and 18 healthy volunteers. BA profiling was done by ultra performance liqu …
Improving prognosis in primary biliary cholangitis - Therapeutic options and strategy.
Harms MH, van Buuren HR, van der Meer AJ. Harms MH, et al. Best Pract Res Clin Gastroenterol. 2018 Jun-Aug;34-35:85-94. doi: 10.1016/j.bpg.2018.06.004. Epub 2018 Jun 14. Best Pract Res Clin Gastroenterol. 2018. PMID: 30343714 Review.
As patients are often asymptomatic, the disease may silently progress towards cirrhosis and liver failure. Timely diagnosis and effective treatment options are of vital importance to improve the prognosis of affected patients. ...While these agents all qualify as potential …
As patients are often asymptomatic, the disease may silently progress towards cirrhosis and liver failure. Timely diagnosis and effec …
A Practical Review of Primary Biliary Cholangitis for the Gastroenterologist.
Onofrio FQ, Hirschfield GM, Gulamhusein AF. Onofrio FQ, et al. Gastroenterol Hepatol (N Y). 2019 Mar;15(3):145-154. Gastroenterol Hepatol (N Y). 2019. PMID: 31061656 Free PMC article.
Primary biliary cholangitis (PBC) is an autoimmune chronic cholestatic liver disease characterized by biliary destruction and progressive intrahepatic cholestasis. PBC primarily affects women in their fifth or sixth decade of life. Although many patients are asym
Primary biliary cholangitis (PBC) is an autoimmune chronic cholestatic liver disease characterized by biliary destruction and progres …
Long-term prognosis of primary biliary cirrhosis (PBC) in Japan and analysis of the factors of stage progression in asymptomatic PBC (a-PBC).
Nakano T, Inoue K, Hirohara J, Arita S, Higuchi K, Omata M, Toda G. Nakano T, et al. Hepatol Res. 2002 Apr;22(4):250-260. doi: 10.1016/s1386-6346(01)00148-6. Hepatol Res. 2002. PMID: 11929710
In particular, we tried to perform multivariate analysis of factors useful in determining prognosis of asymptomatic PBC (a-PBC). ...At the time of diagnosis, patients were classified as a-PBC or symptomatic PBC (s1-PBC; pruritus only, s2- …
In particular, we tried to perform multivariate analysis of factors useful in determining prognosis of asymptomatic PBC (a- …
Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort.
Prince MI, Chetwynd A, Craig WL, Metcalf JV, James OF. Prince MI, et al. Gut. 2004 Jun;53(6):865-70. doi: 10.1136/gut.2003.023937. Gut. 2004. PMID: 15138215 Free PMC article.
BACKGROUND: Many patients with primary biliary cirrhosis (PBC) are asymptomatic at the time of diagnosis. However, because most studies of asymptomatic PBC have been small and from tertiary centres, asymptomatic PBC remains poorly charact …
BACKGROUND: Many patients with primary biliary cirrhosis (PBC) are asymptomatic at the time of diagnosis. However, because mos …
The genetics of primary biliary cholangitis.
Tanaka A, Leung PSC, Gershwin ME. Tanaka A, et al. Curr Opin Gastroenterol. 2019 Mar;35(2):93-98. doi: 10.1097/MOG.0000000000000507. Curr Opin Gastroenterol. 2019. PMID: 30601157 Review.
RECENT FINDINGS: Geo-epidemiological studies in PBC have provided evidence of familial risk; case-control studies and genome wide association studies have identified various human leukocyte antigen (HLA) and non-HLA alleles that are associated with PBC. ...SUMMARY: …
RECENT FINDINGS: Geo-epidemiological studies in PBC have provided evidence of familial risk; case-control studies and genome wide ass …
The diagnosis of primary biliary cirrhosis.
Bowlus CL, Gershwin ME. Bowlus CL, et al. Autoimmun Rev. 2014 Apr-May;13(4-5):441-4. doi: 10.1016/j.autrev.2014.01.041. Epub 2014 Jan 11. Autoimmun Rev. 2014. PMID: 24424173 Free PMC article. Review.
Presently, most cases are asymptomatic and only suspected based upon routine liver tests. Those with symptoms typically complain of pruritus and fatigue. The diagnosis of PBC is based on the presence of at least 2 of 3 key criteria including a persistently elevated …
Presently, most cases are asymptomatic and only suspected based upon routine liver tests. Those with symptoms typically complain of p …
[Primary biliary cirrhosis].
Chon CY, Park JY. Chon CY, et al. Korean J Hepatol. 2006 Sep;12(3):364-72. Korean J Hepatol. 2006. PMID: 16998288 Review. Korean.
Most patients are diagnosed either during the asymptomatic phase of PBC or after presenting with non-specific symptoms. Pruritus and fatigue are the most common symptoms of PBC. The prognosis of PBC has improved significantly during the last few decade …
Most patients are diagnosed either during the asymptomatic phase of PBC or after presenting with non-specific symptoms. Prurit …
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