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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1942 1
1944 2
1945 99
1946 377
1947 410
1948 517
1949 494
1950 1044
1951 1311
1952 1250
1953 1229
1954 1166
1955 1179
1956 1111
1957 1126
1958 1164
1959 978
1960 907
1961 1188
1962 1382
1963 2226
1964 2854
1965 2534
1966 2434
1967 2755
1968 3076
1969 3376
1970 3434
1971 3639
1972 3586
1973 3723
1974 3707
1975 3753
1976 3791
1977 3918
1978 4226
1979 4219
1980 4168
1981 4591
1982 5036
1983 5566
1984 6239
1985 6445
1986 6603
1987 7123
1988 7481
1989 7875
1990 7971
1991 7935
1992 8518
1993 8785
1994 8875
1995 8613
1996 8882
1997 9273
1998 9588
1999 9934
2000 10087
2001 10501
2002 11123
2003 11596
2004 12273
2005 13690
2006 13985
2007 14770
2008 15774
2009 16586
2010 17716
2011 18958
2012 20316
2013 20990
2014 21662
2015 22145
2016 22580
2017 22873
2018 23512
2019 22043
2020 10379
2021 3
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539,356 results
Results by year
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Page 1
Autoimmune Addison's disease - An update on pathogenesis.
Hellesen A, Bratland E, Husebye ES. Hellesen A, et al. Ann Endocrinol (Paris). 2018 Jun;79(3):157-163. doi: 10.1016/j.ando.2018.03.008. Epub 2018 Apr 7. Ann Endocrinol (Paris). 2018. PMID: 29631795 Review.
Autoimmunity against the adrenal cortex is the leading cause of Addison's disease in industrialized countries, with prevalence estimates ranging from 93-220 per million in Europe. ...The autoimmune disease etiology is multifactorial involving variants in immu …
Autoimmunity against the adrenal cortex is the leading cause of Addison's disease in industrialized countries, with prevalence estima …
Human autoimmune diseases: a comprehensive update.
Wang L, Wang FS, Gershwin ME. Wang L, et al. J Intern Med. 2015 Oct;278(4):369-95. doi: 10.1111/joim.12395. Epub 2015 Jul 25. J Intern Med. 2015. PMID: 26212387 Free article. Review.
Despite extensive research, there are no genetic tools that can be used clinically to predict the risk of autoimmune disease. Indeed, the concordance of autoimmune disease in identical twins is 12-67%, highlighting not only a role for environmental fac …
Despite extensive research, there are no genetic tools that can be used clinically to predict the risk of autoimmune disease. …
Prediction and Prevention of Autoimmune Disease in the 21st Century: A Review and Preview.
Rose NR. Rose NR. Am J Epidemiol. 2016 Mar 1;183(5):403-6. doi: 10.1093/aje/kwv292. Epub 2016 Feb 17. Am J Epidemiol. 2016. PMID: 26888748 Review.
Collectively, autoimmune diseases affect some 20 million Americans, predominantly women. Many of these diseases are increasing in frequency in industrialized countries. Treatment of autoimmune diseases improved greatly during the second half of …
Collectively, autoimmune diseases affect some 20 million Americans, predominantly women. Many of these diseases are inc …
[Leptin and autoimmune disease].
Fujita Y. Fujita Y. Nihon Rinsho Meneki Gakkai Kaishi. 2017;40(3):155-159. doi: 10.2177/jsci.40.155. Nihon Rinsho Meneki Gakkai Kaishi. 2017. PMID: 28747601 Free article. Review. Japanese.
On the other hand, the leptin receptor is also expressed in hematopoietic cells and its action on the immune system has become known, and the significance of leptin in autoimmune diseases has gradually become clear. It has been shown that leptin acts as an exacerbat …
On the other hand, the leptin receptor is also expressed in hematopoietic cells and its action on the immune system has become known, and th …
Gene Therapy for Autoimmune Disease.
Shu SA, Wang J, Tao MH, Leung PS. Shu SA, et al. Clin Rev Allergy Immunol. 2015 Oct;49(2):163-76. doi: 10.1007/s12016-014-8451-x. Clin Rev Allergy Immunol. 2015. PMID: 25277817 Review.
Advances in understanding the immunological and molecular basis of autoimmune diseases have made gene therapy a promising approach to treat the affected patients. ...Here, we summarize the recent progress in identifying genes responsible for autoimmune dis
Advances in understanding the immunological and molecular basis of autoimmune diseases have made gene therapy a promising appr …
Sex Hormones in Acquired Immunity and Autoimmune Disease.
Moulton VR. Moulton VR. Front Immunol. 2018 Oct 4;9:2279. doi: 10.3389/fimmu.2018.02279. eCollection 2018. Front Immunol. 2018. PMID: 30337927 Free PMC article. Review.
Paradoxically, the stronger immune response comes at a steep price, which is the high incidence of autoimmune diseases in women. ...This review focuses on the role of sex hormones particularly estrogen, in the adaptive immune response, in health, and autoimmune
Paradoxically, the stronger immune response comes at a steep price, which is the high incidence of autoimmune diseases in wome …
Stress as a trigger of autoimmune disease.
Stojanovich L, Marisavljevich D. Stojanovich L, et al. Autoimmun Rev. 2008 Jan;7(3):209-13. doi: 10.1016/j.autrev.2007.11.007. Epub 2007 Nov 29. Autoimmun Rev. 2008. PMID: 18190880 Review.
The etiology of autoimmune diseases is multifactorial: genetic, environmental, hormonal, and immunological factors are all considered important in their development. ...The treatment of autoimmune disease should thus include stress management and behav …
The etiology of autoimmune diseases is multifactorial: genetic, environmental, hormonal, and immunological factors are all con …
Use of Immune Checkpoint Inhibitors in the Treatment of Patients With Cancer and Preexisting Autoimmune Disease: A Systematic Review.
Abdel-Wahab N, Shah M, Lopez-Olivo MA, Suarez-Almazor ME. Abdel-Wahab N, et al. Ann Intern Med. 2018 Jan 16;168(2):121-130. doi: 10.7326/M17-2073. Epub 2018 Jan 2. Ann Intern Med. 2018. PMID: 29297009
PURPOSE: To summarize the evidence on adverse events associated with CPIs in patients with cancer and preexisting autoimmune disease. ...PRIMARY FUNDING SOURCE: National Institute of Arthritis and Musculoskeletal and Skin Diseases....
PURPOSE: To summarize the evidence on adverse events associated with CPIs in patients with cancer and preexisting autoimmune disea
Type I Interferons in Autoimmune Disease.
Crow MK, Olferiev M, Kirou KA. Crow MK, et al. Annu Rev Pathol. 2019 Jan 24;14:369-393. doi: 10.1146/annurev-pathol-020117-043952. Epub 2018 Oct 17. Annu Rev Pathol. 2019. PMID: 30332560 Review.
Type I interferons, which make up the first cytokine family to be described and are the essential mediators of antivirus host defense, have emerged as central elements in the immunopathology of systemic autoimmune diseases, with systemic lupus erythematosus as the p …
Type I interferons, which make up the first cytokine family to be described and are the essential mediators of antivirus host defense, have …
Pathogen infection and autoimmune disease.
Christen U. Christen U. Clin Exp Immunol. 2019 Jan;195(1):10-14. doi: 10.1111/cei.13239. Clin Exp Immunol. 2019. PMID: 30569518 Free PMC article. No abstract available.
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