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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1965 1
1966 1
1967 3
1968 2
1969 5
1970 2
1971 7
1972 11
1973 7
1974 7
1975 19
1976 23
1977 26
1978 17
1979 27
1980 38
1981 42
1982 41
1983 35
1984 36
1985 44
1986 32
1987 37
1988 33
1989 22
1990 29
1991 27
1992 29
1993 35
1994 17
1995 30
1996 31
1997 49
1998 32
1999 44
2000 76
2001 102
2002 99
2003 131
2004 174
2005 268
2006 476
2007 717
2008 1060
2009 1428
2010 1863
2011 2299
2012 3001
2013 3659
2014 4309
2015 4969
2016 5469
2017 6491
2018 7174
2019 8124
2020 7335
2021 10
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53,474 results
Results by year
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Page 1
Autophagy-monitoring and autophagy-deficient mice.
Kuma A, Komatsu M, Mizushima N. Kuma A, et al. Autophagy. 2017 Oct 3;13(10):1619-1628. doi: 10.1080/15548627.2017.1343770. Epub 2017 Aug 18. Autophagy. 2017. PMID: 28820286 Free PMC article. Review.
Specific identification of autophagy-related structures is important to evaluate autophagic activity, and specific ablation of autophagy-related genes is a critical means to determine the requirements of autophagy. Here, we review currently available mouse mo …
Specific identification of autophagy-related structures is important to evaluate autophagic activity, and specific ablation of aut
Autophagy: cellular and molecular mechanisms.
Glick D, Barth S, Macleod KF. Glick D, et al. J Pathol. 2010 May;221(1):3-12. doi: 10.1002/path.2697. J Pathol. 2010. PMID: 20225336 Free PMC article. Review.
Thus, autophagy is generally thought of as a survival mechanism, although its deregulation has been linked to non-apoptotic cell death. Autophagy can be either non-selective or selective in the removal of specific organelles, ribosomes and protein aggregates, althou …
Thus, autophagy is generally thought of as a survival mechanism, although its deregulation has been linked to non-apoptotic cell deat …
An overview of autophagy: morphology, mechanism, and regulation.
Parzych KR, Klionsky DJ. Parzych KR, et al. Antioxid Redox Signal. 2014 Jan 20;20(3):460-73. doi: 10.1089/ars.2013.5371. Epub 2013 Aug 2. Antioxid Redox Signal. 2014. PMID: 23725295 Free PMC article. Review.
SIGNIFICANCE: Autophagy is a highly conserved eukaryotic cellular recycling process. Through the degradation of cytoplasmic organelles, proteins, and macromolecules, and the recycling of the breakdown products, autophagy plays important roles in cell survival and ma …
SIGNIFICANCE: Autophagy is a highly conserved eukaryotic cellular recycling process. Through the degradation of cytoplasmic organelle …
Autophagy: renovation of cells and tissues.
Mizushima N, Komatsu M. Mizushima N, et al. Cell. 2011 Nov 11;147(4):728-41. doi: 10.1016/j.cell.2011.10.026. Cell. 2011. PMID: 22078875 Free article. Review.
However, the purpose of autophagy is not the simple elimination of materials, but instead, autophagy serves as a dynamic recycling system that produces new building blocks and energy for cellular renovation and homeostasis. Here we provide a multidisciplinary review …
However, the purpose of autophagy is not the simple elimination of materials, but instead, autophagy serves as a dynamic recyc …
Biological Functions of Autophagy Genes: A Disease Perspective.
Levine B, Kroemer G. Levine B, et al. Cell. 2019 Jan 10;176(1-2):11-42. doi: 10.1016/j.cell.2018.09.048. Cell. 2019. PMID: 30633901 Free PMC article. Review.
The lysosomal degradation pathway of autophagy plays a fundamental role in cellular, tissue, and organismal homeostasis and is mediated by evolutionarily conserved autophagy-related (ATG) genes. ...Autophagy selectively targets dysfunctional organelles, intra …
The lysosomal degradation pathway of autophagy plays a fundamental role in cellular, tissue, and organismal homeostasis and is mediat …
Targeting autophagy in cancer.
Onorati AV, Dyczynski M, Ojha R, Amaravadi RK. Onorati AV, et al. Cancer. 2018 Aug;124(16):3307-3318. doi: 10.1002/cncr.31335. Epub 2018 Apr 19. Cancer. 2018. PMID: 29671878 Free PMC article. Review.
Dysregulated autophagy has implications in health and disease. Specifically, in cancer, autophagy plays a dichotomous role by inhibiting tumor initiation but supporting tumor progression. ...In this review of the literature, the authors present fundamental advances …
Dysregulated autophagy has implications in health and disease. Specifically, in cancer, autophagy plays a dichotomous role by …
Regulation of selective autophagy: the p62/SQSTM1 paradigm.
Lamark T, Svenning S, Johansen T. Lamark T, et al. Essays Biochem. 2017 Dec 12;61(6):609-624. doi: 10.1042/EBC20170035. Print 2017 Dec 12. Essays Biochem. 2017. PMID: 29233872 Review.
In selective autophagy, cytoplasmic components are selected and tagged before being sequestered into an autophagosome by means of selective autophagy receptors such as p62/SQSTM1. ...Regulation of the capacity of the core autophagy machinery also affects sele …
In selective autophagy, cytoplasmic components are selected and tagged before being sequestered into an autophagosome by means of sel …
Autophagy: The spotlight for cellular stress responses.
Ravanan P, Srikumar IF, Talwar P. Ravanan P, et al. Life Sci. 2017 Nov 1;188:53-67. doi: 10.1016/j.lfs.2017.08.029. Epub 2017 Sep 1. Life Sci. 2017. PMID: 28866100 Review.
Similarly, inhibiting autophagy would contribute in the treatment of cancer. However, understanding the biology of autophagy regulation requires pharmacologically active compounds which modulate the autophagy process. ...Both induction and inhibition of au
Similarly, inhibiting autophagy would contribute in the treatment of cancer. However, understanding the biology of autophagy r …
Autophagy and multidrug resistance in cancer.
Li YJ, Lei YH, Yao N, Wang CR, Hu N, Ye WC, Zhang DM, Chen ZS. Li YJ, et al. Chin J Cancer. 2017 Jun 24;36(1):52. doi: 10.1186/s40880-017-0219-2. Chin J Cancer. 2017. PMID: 28646911 Free PMC article. Review.
Autophagy induced by anticancer drugs could also activate apoptosis signaling pathways in MDR cells, facilitating MDR reversal. Therefore, research on the regulation of autophagy to combat MDR is expanding and is becoming increasingly important. We summarize advance
Autophagy induced by anticancer drugs could also activate apoptosis signaling pathways in MDR cells, facilitating MDR reversal. There
Autophagy and intermittent fasting: the connection for cancer therapy?
Antunes F, Erustes AG, Costa AJ, Nascimento AC, Bincoletto C, Ureshino RP, Pereira GJS, Smaili SS. Antunes F, et al. Clinics (Sao Paulo). 2018 Dec 10;73(suppl 1):e814s. doi: 10.6061/clinics/2018/e814s. Clinics (Sao Paulo). 2018. PMID: 30540126 Free PMC article. Review.
Dysfunctional autophagy contributes to many diseases, including cancer. Autophagy can suppress or promote tumors depending on the developmental stage and tumor type, and modulating autophagy for cancer treatment is an interesting therapeutic approach currentl …
Dysfunctional autophagy contributes to many diseases, including cancer. Autophagy can suppress or promote tumors depending on …
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