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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 13
2008 33
2009 47
2010 51
2011 59
2012 59
2013 49
2014 57
2015 42
2016 35
2017 43
2018 46
2019 41
2020 28
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531 results
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Page 1
Crohn's disease.
Baumgart DC, Sandborn WJ. Baumgart DC, et al. Lancet. 2012 Nov 3;380(9853):1590-605. doi: 10.1016/S0140-6736(12)60026-9. Epub 2012 Aug 20. Lancet. 2012. PMID: 22914295 Free article. Review.
Crohn's disease is a relapsing systemic inflammatory disease, mainly affecting the gastrointestinal tract with extraintestinal manifestations and associated immune disorders. ...We discuss the epidemiology, immunobiology, amd natural history of Croh
Crohn's disease is a relapsing systemic inflammatory disease, mainly affecting the gastrointestinal tract with e
Mechanisms and function of autophagy in intestinal disease.
Lassen KG, Xavier RJ. Lassen KG, et al. Autophagy. 2018;14(2):216-220. doi: 10.1080/15548627.2017.1389358. Epub 2018 Jan 29. Autophagy. 2018. PMID: 29130415 Free PMC article. Review.
The discovery of numerous genetic variants in the human genome that are associated with inflammatory bowel disease (IBD) has revealed critical pathways that play important roles in intestinal homeostasis. ...This review highlights recent work on the functional characteriza …
The discovery of numerous genetic variants in the human genome that are associated with inflammatory bowel disease (IBD) has revealed …
Autophagy: renovation of cells and tissues.
Mizushima N, Komatsu M. Mizushima N, et al. Cell. 2011 Nov 11;147(4):728-41. doi: 10.1016/j.cell.2011.10.026. Cell. 2011. PMID: 22078875 Free article. Review.
Here we provide a multidisciplinary review of our current understanding of autophagy's role in metabolic adaptation, intracellular quality control, and renovation during development and differentiation. We also explore how recent mouse models in combination with adv …
Here we provide a multidisciplinary review of our current understanding of autophagy's role in metabolic adaptation, intracell …
Gut dysbiosis and paediatric Crohn's disease.
Brusaferro A, Cavalli E, Farinelli E, Cozzali R, Principi N, Esposito S. Brusaferro A, et al. J Infect. 2019 Jan;78(1):1-7. doi: 10.1016/j.jinf.2018.10.005. Epub 2018 Oct 16. J Infect. 2019. PMID: 30336176 Review.
OBJECTIVES: The main objective of this manuscript is to discuss our present knowledge of the relationships between dysbiosis and paediatric Crohn's disease (CD). ...METHODS: PubMed was used to search for all of the studies published from January 2008 to June …
OBJECTIVES: The main objective of this manuscript is to discuss our present knowledge of the relationships between dysbiosis and paediatric …
Autophagy and the endo/exosomal pathways in health and disease.
Papandreou ME, Tavernarakis N. Papandreou ME, et al. Biotechnol J. 2017 Jan;12(1). doi: 10.1002/biot.201600175. Epub 2016 Dec 15. Biotechnol J. 2017. PMID: 27976834 Review.
Cell homeostasis requires the concerted action of cellular pathways involved in degradation, trafficking and intercellular communication, which are interlinked to satisfy the cell's needs upon demand. ...In addition, we discuss novel methodologies that have recently been d …
Cell homeostasis requires the concerted action of cellular pathways involved in degradation, trafficking and intercellular communication, wh …
The Selective Autophagy Receptor Optineurin in Crohn's Disease.
Tschurtschenthaler M, Adolph TE. Tschurtschenthaler M, et al. Front Immunol. 2018 Apr 10;9:766. doi: 10.3389/fimmu.2018.00766. eCollection 2018. Front Immunol. 2018. PMID: 29692785 Free PMC article. Review.
Perturbations of ER and autophagy functions have been linked to inflammatory bowel disease (IBD) and specifically Crohn's disease. Collectively, these studies may explain how perturbations at the ER can be resolved by selective autophagy
Perturbations of ER and autophagy functions have been linked to inflammatory bowel disease (IBD) and specifically Crohn
The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy.
Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S. Mehto S, et al. Mol Cell. 2019 Feb 7;73(3):429-445.e7. doi: 10.1016/j.molcel.2018.11.018. Epub 2019 Jan 3. Mol Cell. 2019. PMID: 30612879 Free PMC article.
Several large-scale genome-wide association studies genetically linked IRGM to Crohn's disease and other inflammatory disorders in which the IRGM appears to have a protective function. ...By suppressing inflammasome activation, IRGM/Irgm1 protects from pyropt …
Several large-scale genome-wide association studies genetically linked IRGM to Crohn's disease and other inflammatory d …
Crohn's Disease: Potential Drugs for Modulation of Autophagy.
Azzman N. Azzman N. Medicina (Kaunas). 2019 May 29;55(6):224. doi: 10.3390/medicina55060224. Medicina (Kaunas). 2019. PMID: 31146413 Free PMC article. Review.
The modulation of autophagy has shown greatest promise in Crohn's disease as most of autophagy drugs involved in these diseases are currently under clinical trials and some has been approved by Food and Drug Administration. This review article d …
The modulation of autophagy has shown greatest promise in Crohn's disease as most of autophagy drugs invo …
Autophagy and Crohn's disease.
Nguyen HT, Lapaquette P, Bringer MA, Darfeuille-Michaud A. Nguyen HT, et al. J Innate Immun. 2013;5(5):434-43. doi: 10.1159/000345129. Epub 2013 Jan 15. J Innate Immun. 2013. PMID: 23328432 Free PMC article. Review.
Advances in genetics have shed light on the molecular basis of Crohn's disease (CD) predisposition and pathogenesis, via linkage disequilibrium analysis to genome-wide association studies. ...Remarkably, polymorphisms in autophagy genes, such as ATG16L …
Advances in genetics have shed light on the molecular basis of Crohn's disease (CD) predisposition and pathogenesis, vi …
NOD2 and bacterial recognition as therapeutic targets for Crohn's disease.
de Bruyn M, Vermeire S. de Bruyn M, et al. Expert Opin Ther Targets. 2017 Dec;21(12):1123-1139. doi: 10.1080/14728222.2017.1397627. Epub 2017 Nov 2. Expert Opin Ther Targets. 2017. PMID: 29096557 Review.
Crohn's disease (CD) is a chronic, disabling disease of the gastrointestinal tract that mostly affects young adults. Despite extensive research, the pathogenesis of CD is still not completely understood. ...Expert opinion: Almost 2 decades after the id
Crohn's disease (CD) is a chronic, disabling disease of the gastrointestinal tract that mostly affects young adu
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