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Year Number of Results
1990 1
1991 1
1994 4
1995 2
1996 1
1997 2
1998 1
1999 4
2000 3
2001 1
2002 3
2003 4
2004 2
2005 4
2006 5
2007 5
2008 10
2009 5
2010 8
2011 8
2012 4
2013 6
2014 4
2015 2
2016 6
2017 4
2018 5
2019 9
2020 7
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117 results
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Page 1
ABCB4 Gene Aberrations in Human Liver Disease: An Evolving Spectrum.
Reichert MC, Lammert F. Reichert MC, et al. Semin Liver Dis. 2018 Nov;38(4):299-307. doi: 10.1055/s-0038-1667299. Epub 2018 Oct 24. Semin Liver Dis. 2018. PMID: 30357767 Review.
LPAC and ICP are usually caused by monoallelic variants, whereas patients affected by PFIC3 are homozygous or compound heterozygous carriers of ABCB4 variants. Treatment with ursodeoxycholic acid is often effective, but as the more severe forms of ABCB4 deficiency p …
LPAC and ICP are usually caused by monoallelic variants, whereas patients affected by PFIC3 are homozygous or compound heterozygous carriers …
Treatment of primary sclerosing cholangitis in children.
Laborda TJ, Jensen MK, Kavan M, Deneau M. Laborda TJ, et al. World J Hepatol. 2019 Jan 27;11(1):19-36. doi: 10.4254/wjh.v11.i1.19. World J Hepatol. 2019. PMID: 30705716 Free PMC article. Review.
Within ten years of diagnosis, 50% of children will develop clinical complications including 30% requiring liver transplantation. Cholangiocarcinoma is a rare but serious complication affecting 1% of children. Ursodeoxycholic acid and oral vancomycin therapy …
Within ten years of diagnosis, 50% of children will develop clinical complications including 30% requiring liver transplantation. Cholang
Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management.
Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD. Eaton JE, et al. Gastroenterology. 2013 Sep;145(3):521-36. doi: 10.1053/j.gastro.2013.06.052. Epub 2013 Jul 1. Gastroenterology. 2013. PMID: 23827861 Free PMC article. Review.
Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer.
Liu T, Yang H, Fan W, Tu J, Li TWH, Wang J, Shen H, Yang J, Xiong T, Steggerda J, Liu Z, Noureddin M, Maldonado SS, Annamalai A, Seki E, Mato JM, Lu SC. Liu T, et al. Gastroenterology. 2018 Aug;155(2):557-571.e14. doi: 10.1053/j.gastro.2018.04.032. Epub 2018 May 5. Gastroenterology. 2018. PMID: 29733835 Free PMC article.
BACKGROUND & AIMS: MAF bZIP transcription factor G (MAFG) is activated by the farnesoid X receptor to repress bile acid synthesis. However, expression of MAFG increases during cholestatic liver injury in mice and in cholangiocarcinomas. ...We studied mechanisms …
BACKGROUND & AIMS: MAF bZIP transcription factor G (MAFG) is activated by the farnesoid X receptor to repress bile acid synthesis …
An Overview on Primary Sclerosing Cholangitis.
Vlăduţ C, Ciocîrlan M, Bilous D, Șandru V, Stan-Ilie M, Panic N, Becheanu G, Jinga M, Costache RS, Costache DO, Diculescu M. Vlăduţ C, et al. J Clin Med. 2020 Mar 11;9(3):754. doi: 10.3390/jcm9030754. J Clin Med. 2020. PMID: 32168787 Free PMC article. Review.
It shows multifocal short biliary duct strictures leading to the "beaded" aspect. Cholangiocarcinoma and colorectal adenocarcinoma are the most feared complications in patients with Primary sclerosing cholangitis (PSC). ...The lack of efficient curative medical treatment m …
It shows multifocal short biliary duct strictures leading to the "beaded" aspect. Cholangiocarcinoma and colorectal adenocarcinoma ar …
Imaging Features of Primary Sclerosing Cholangitis: From Diagnosis to Liver Transplant Follow-up.
Khoshpouri P, Habibabadi RR, Hazhirkarzar B, Ameli S, Ghadimi M, Ghasabeh MA, Menias CO, Kim A, Li Z, Kamel IR. Khoshpouri P, et al. Radiographics. 2019 Nov-Dec;39(7):1938-1964. doi: 10.1148/rg.2019180213. Epub 2019 Oct 18. Radiographics. 2019. PMID: 31626561 Review.
Patients are predisposed to various hepatic and extrahepatic deteriorating complications, such as bile duct and gallbladder calculi, acute bacterial cholangitis, liver abscess, and portal hypertension, as well as malignancies including cholangiocarcinoma (CCA), gallbladder …
Patients are predisposed to various hepatic and extrahepatic deteriorating complications, such as bile duct and gallbladder calculi, acute b …
[Primary sclerosing cholangitis : Current diagnostics and treatment].
Liwinski T, Schramm C. Liwinski T, et al. Internist (Berl). 2018 Jun;59(6):551-559. doi: 10.1007/s00108-018-0428-z. Internist (Berl). 2018. PMID: 29700559 Review. German.
The diagnosis is established based on detection of typical cholangiographic lesions of the bile ducts and exclusion of secondary causes of sclerosing cholangitis. There is no approved medical treatment, but in Germany ursodeoxycholic acid is frequently used. Clinica …
The diagnosis is established based on detection of typical cholangiographic lesions of the bile ducts and exclusion of secondary causes of s …
[Immune-mediated cholangiopathies : Diagnostic and therapeutic challenges].
Herta T, Beuers U. Herta T, et al. Radiologe. 2019 Apr;59(4):348-356. doi: 10.1007/s00117-019-0513-x. Radiologe. 2019. PMID: 30874827 Review. German.
DIAGNOSIS: The diagnostic work-up involves the patient's history, physical examination, serological tests, abdominal ultrasonography, magnetic resonance cholangiopancreatography (MRCP) and, where necessary, liver biopsy and genetic testing. THERAPY: Ursodeoxycholic acid
DIAGNOSIS: The diagnostic work-up involves the patient's history, physical examination, serological tests, abdominal ultrasonography, magnet …
Ursodeoxycholic acid-conjugated chitosan for photodynamic treatment of HuCC-T1 human cholangiocarcinoma cells.
Lee HM, Jeong YI, Kim DH, Kwak TW, Chung CW, Kim CH, Kang DH. Lee HM, et al. Int J Pharm. 2013 Sep 15;454(1):74-81. doi: 10.1016/j.ijpharm.2013.06.035. Epub 2013 Jul 6. Int J Pharm. 2013. PMID: 23834828
Chitosan was hydrophobically modified with ursodeoxycholic acid (UDCA) to fabricate nano-photosensitizer for photodynamic therapy (PDT) of HuCC-T1 cholangiocarcinoma cells. ...We suggest that Ce6-incorporated ChitoUDCA nanoparticles are promising candidates f …
Chitosan was hydrophobically modified with ursodeoxycholic acid (UDCA) to fabricate nano-photosensitizer for photodynamic ther …
The incidence of cholangiocarcinoma in primary sclerosing cholangitis after long-time treatment with ursodeoxycholic acid.
Rudolph G, Kloeters-Plachky P, Rost D, Stiehl A. Rudolph G, et al. Eur J Gastroenterol Hepatol. 2007 Jun;19(6):487-91. doi: 10.1097/MEG.0b013e3281108068. Eur J Gastroenterol Hepatol. 2007. PMID: 17489059
Ursodeoxycholic acid may possibly influence the incidence of cholangiocarcinoma in man. ...The Kaplan-Meier estimate of cholangiocarcinoma incidence during ursodeoxycholic acid treatment reached a plateau after 8.3 years. ...
Ursodeoxycholic acid may possibly influence the incidence of cholangiocarcinoma in man. ...The Kaplan-Meier estimate of
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