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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 2
1975 57
1976 98
1977 115
1978 157
1979 174
1980 289
1981 286
1982 352
1983 518
1984 622
1985 679
1986 717
1987 704
1988 635
1989 816
1990 782
1991 776
1992 784
1993 788
1994 788
1995 905
1996 1066
1997 1124
1998 1251
1999 1475
2000 1688
2001 1942
2002 2360
2003 2489
2004 2832
2005 3211
2006 3107
2007 3053
2008 2828
2009 2828
2010 2859
2011 2842
2012 2816
2013 2946
2014 2814
2015 2731
2016 2530
2017 2484
2018 2439
2019 2262
2020 1395
2021 1
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64,700 results
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Page 1
Pharmacogenomics of cyclooxygenases.
Agúndez JA, Blanca M, Cornejo-García JA, García-Martín E. Agúndez JA, et al. Pharmacogenomics. 2015;16(5):501-22. doi: 10.2217/pgs.15.6. Pharmacogenomics. 2015. PMID: 25916522 Review.
Cyclooxygenases (COX-1 and COX-2) are key enzymes in several physiopathological processes. Many adverse drugs reactions to NSAIDs are attributable to COX-inhibition. ...
Cyclooxygenases (COX-1 and COX-2) are key enzymes in several physiopathological processes. Many adverse drugs reactions to NSAIDs are
The ambidextrous cyclooxygenase: an enduring target.
Bapna M, Chauhan LS. Bapna M, et al. Inflamm Allergy Drug Targets. 2015;13(6):387-92. doi: 10.2174/1871528114666150401105545. Inflamm Allergy Drug Targets. 2015. PMID: 25827631 Review.
Inhibitors of cyclooxygenases: mechanisms, selectivity and uses.
Botting RM. Botting RM. J Physiol Pharmacol. 2006 Nov;57 Suppl 5:113-24. J Physiol Pharmacol. 2006. PMID: 17218763 Review.
They are made by the bifunctional enzyme, cyclooxygenase, which has both cyclooxygenase and peroxidase activities in the same molecule. ...Thus, aspirin-like drugs exert their anti-inflammatory, antipyretic and analgesic effects by inhibition of cyclooxygenase
They are made by the bifunctional enzyme, cyclooxygenase, which has both cyclooxygenase and peroxidase activities in the same …
Beyond cyclooxygenase.
Breyer MD. Breyer MD. Kidney Int. 2002 Nov;62(5):1898-9. doi: 10.1046/j.1523-1755.2002.00645.x. Kidney Int. 2002. PMID: 12371995 Free article. Review. No abstract available.
[Cyclooxygenases].
Eschwège P, de Ledinghen V, Camilli T, Kulkarni S, Dalbagni G, Droupy S, Jardin A, Benoît G, Weksler BB. Eschwège P, et al. Presse Med. 2001 Mar 17;30(10):511-4. Presse Med. 2001. PMID: 11307497 French.
TWO ISOFORMS: There are two isoforms of cyclooxygenase (COX) with similar structure and metabolic activity. COX-1 is a constitutional enzyme. ...CYCLOOXYGENASE-1: COX-1 is present in most tissues, particularly in the kidney, the digestive tract mucosa, platelets, br …
TWO ISOFORMS: There are two isoforms of cyclooxygenase (COX) with similar structure and metabolic activity. COX-1 is a constitutional …
Cyclooxygenase in biology and disease.
Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LB, Lipsky PE. Dubois RN, et al. FASEB J. 1998 Sep;12(12):1063-73. FASEB J. 1998. PMID: 9737710 Free article. Review.
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. In the pas
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 y
Expression and localization of cyclooxygenases in the oviduct of laying hens during the ovulatory cycle.
Elhamouly M, Isobe N, Yoshimura Y. Elhamouly M, et al. Theriogenology. 2017 Oct 1;101:1-7. doi: 10.1016/j.theriogenology.2017.06.015. Epub 2017 Jun 13. Theriogenology. 2017. PMID: 28708506
However, little is known about the expression and localization of the rate-limiting cyclooxygenases (COX-1 and COX-2) in the oviduct. ...
However, little is known about the expression and localization of the rate-limiting cyclooxygenases (COX-1 and COX-2) in the oviduct. …
Cox-2-selective inhibitors: the new super aspirins.
DeWitt DL. DeWitt DL. Mol Pharmacol. 1999 Apr;55(4):625-31. Mol Pharmacol. 1999. PMID: 10101019 Review. No abstract available.
Cyclooxygenase-2 inhibitors.
Gajraj NM. Gajraj NM. Anesth Analg. 2003 Jun;96(6):1720-38. doi: 10.1213/01.ane.0000061461.55712.c5. Anesth Analg. 2003. PMID: 12761004 Review. No abstract available.
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