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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1939 1
1941 1
1942 2
1944 1
1945 2
1946 17
1947 6
1948 19
1949 19
1950 34
1951 31
1952 25
1953 29
1954 19
1955 32
1956 54
1957 58
1958 54
1959 87
1960 61
1961 91
1962 107
1963 147
1964 159
1965 154
1966 127
1967 192
1968 215
1969 211
1970 284
1971 214
1972 242
1973 264
1974 256
1975 251
1976 311
1977 269
1978 295
1979 342
1980 347
1981 326
1982 366
1983 414
1984 429
1985 488
1986 539
1987 532
1988 628
1989 670
1990 813
1991 858
1992 939
1993 900
1994 980
1995 1064
1996 1081
1997 1074
1998 1057
1999 1131
2000 1225
2001 1278
2002 1327
2003 1312
2004 1347
2005 1476
2006 1505
2007 1547
2008 1599
2009 1648
2010 1875
2011 1940
2012 2107
2013 2211
2014 2341
2015 2412
2016 2480
2017 2423
2018 2580
2019 2617
2020 3048
2021 283
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Search Results

55,554 results
Results by year
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Page 1
Cystic fibrosis.
Elborn JS. Elborn JS. Lancet. 2016 Nov 19;388(10059):2519-2531. doi: 10.1016/S0140-6736(16)00576-6. Epub 2016 Apr 29. Lancet. 2016. PMID: 27140670 Review.
The disease is caused by mutation of a gene that encodes a chloride-conducting transmembrane channel called the cystic fibrosis transmembrane conductance regulator (CFTR), which regulates anion transport and mucociliary clearance in the airways. ...Further sm …
The disease is caused by mutation of a gene that encodes a chloride-conducting transmembrane channel called the cystic fibrosis …
Cystic Fibrosis Revisited - a Review Study.
Klimova B, Kuca K, Novotny M, Maresova P. Klimova B, et al. Med Chem. 2017;13(2):102-109. doi: 10.2174/1573406412666160608113235. Med Chem. 2017. PMID: 27292156 Review.
BACKGROUND: Cystic fibrosis (CF) is an incurable, chronic disease, which causes severe damages to respiratory and digestive tracts. ...This disease is caused by defects in CF genes, the so-called mutations in cystic fibrosis transmembrane conductance r …
BACKGROUND: Cystic fibrosis (CF) is an incurable, chronic disease, which causes severe damages to respiratory and digestive tr …
Cystic fibrosis: current therapeutic targets and future approaches.
Rafeeq MM, Murad HAS. Rafeeq MM, et al. J Transl Med. 2017 Apr 27;15(1):84. doi: 10.1186/s12967-017-1193-9. J Transl Med. 2017. PMID: 28449677 Free PMC article. Review.
OBJECTIVES: Study of currently approved drugs and exploration of future clinical development pipeline therapeutics for cystic fibrosis, and possible limitations in their use. METHODS: Extensive literature search using individual and a combination of key words relate …
OBJECTIVES: Study of currently approved drugs and exploration of future clinical development pipeline therapeutics for cystic fibr …
Cystic fibrosis.
Ratjen F, Bell SC, Rowe SM, Goss CH, Quittner AL, Bush A. Ratjen F, et al. Nat Rev Dis Primers. 2015 May 14;1:15010. doi: 10.1038/nrdp.2015.10. Nat Rev Dis Primers. 2015. PMID: 27189798 Free PMC article. Review.
Cystic fibrosis is an autosomal recessive, monogenetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. ...CFTR dysfunction affects many organs; however, lung disease is responsible for …
Cystic fibrosis is an autosomal recessive, monogenetic disorder caused by mutations in the cystic fibrosis trans …
CFTR: cystic fibrosis and beyond.
Mall MA, Hartl D. Mall MA, et al. Eur Respir J. 2014 Oct;44(4):1042-54. doi: 10.1183/09031936.00228013. Epub 2014 Jun 12. Eur Respir J. 2014. PMID: 24925916 Free article.
Cystic fibrosis (CF) remains the most common fatal hereditary lung disease. The discovery of the cystic fibrosis transmembrane conductance regulator (CFTR) gene 25 years ago set the stage for: 1) unravelling the molecular and cellular basis of C …
Cystic fibrosis (CF) remains the most common fatal hereditary lung disease. The discovery of the cystic fibrosis …
Genetics of cystic fibrosis: CFTR mutation classifications toward genotype-based CF therapies.
Fanen P, Wohlhuter-Haddad A, Hinzpeter A. Fanen P, et al. Int J Biochem Cell Biol. 2014 Jul;52:94-102. doi: 10.1016/j.biocel.2014.02.023. Epub 2014 Mar 12. Int J Biochem Cell Biol. 2014. PMID: 24631642 Free article. Review.
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes an epithelial anion channel. ...This review presents the current CFTR mutatio …
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane …
Cystic fibrosis: a clinical view.
Castellani C, Assael BM. Castellani C, et al. Cell Mol Life Sci. 2017 Jan;74(1):129-140. doi: 10.1007/s00018-016-2393-9. Epub 2016 Oct 5. Cell Mol Life Sci. 2017. PMID: 27709245 Review.
Cystic fibrosis (CF), a monogenic disease caused by mutations in the CFTR gene on chromosome 7, is complex and greatly variable in clinical expression. ...The great number of mutations and their diverse effects on the CFTR protein account only partiall …
Cystic fibrosis (CF), a monogenic disease caused by mutations in the CFTR gene on chromosome 7, is complex and greatly …
Cystic Fibrosis: Pathophysiology of Lung Disease.
Bergeron C, Cantin AM. Bergeron C, et al. Semin Respir Crit Care Med. 2019 Dec;40(6):715-726. doi: 10.1055/s-0039-1694021. Epub 2019 Oct 28. Semin Respir Crit Care Med. 2019. PMID: 31659725 Review.
Cystic fibrosis (CF) is a common, life-threatening, multisystemic, autosomal recessive disorder. In the last few years, giant steps have been made with regard to the understanding of CF pathophysiology, allowing the scientific community to propose mechanisms that ca …
Cystic fibrosis (CF) is a common, life-threatening, multisystemic, autosomal recessive disorder. In the last few years, giant …
The diagnosis of cystic fibrosis.
De Boeck K, Vermeulen F, Dupont L. De Boeck K, et al. Presse Med. 2017 Jun;46(6 Pt 2):e97-e108. doi: 10.1016/j.lpm.2017.04.010. Epub 2017 May 31. Presse Med. 2017. PMID: 28576637 Review.
Establishing the diagnosis of cystic fibrosis (CF) is straight forward in the majority of patients: they present with a clear clinical picture (most frequently chronic respiratory symptoms plus malabsorption), the sweat chloride value is>60mmol/L and two known di …
Establishing the diagnosis of cystic fibrosis (CF) is straight forward in the majority of patients: they present with a clear …
Progress in therapies for cystic fibrosis.
De Boeck K, Amaral MD. De Boeck K, et al. Lancet Respir Med. 2016 Aug;4(8):662-674. doi: 10.1016/S2213-2600(16)00023-0. Epub 2016 Apr 1. Lancet Respir Med. 2016. PMID: 27053340 Review.
Standard follow-up and symptomatic treatment have allowed most patients with cystic fibrosis to live to young adulthood. However, many patients still die prematurely from respiratory insufficiency. Hence, further investigations to improve these therapies are importa …
Standard follow-up and symptomatic treatment have allowed most patients with cystic fibrosis to live to young adulthood. Howev …
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