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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1970 1
1975 2
1976 1
2000 3
2001 1
2002 4
2003 3
2004 4
2005 5
2006 2
2007 2
2008 2
2009 3
2010 6
2011 5
2012 5
2013 8
2014 12
2015 19
2016 16
2017 12
2018 23
2019 11
2020 11
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145 results
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Page 1
Fibrates and cholestasis.
Ghonem NS, Assis DN, Boyer JL. Ghonem NS, et al. Hepatology. 2015 Aug;62(2):635-43. doi: 10.1002/hep.27744. Epub 2015 Mar 23. Hepatology. 2015. PMID: 25678132 Free PMC article. Review.
Cholestasis, including primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC), results from an impairment or disruption of bile production and causes intracellular retention of toxic bile constituents, including bile salts. If left un …
Cholestasis, including primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC), results from an …
Bezafibrate in Primary Biliary Cholangitis.
Corpechot C, Chazouillères O, Rousseau A. Corpechot C, et al. N Engl J Med. 2018 Sep 6;379(10):985. doi: 10.1056/NEJMc1809061. N Engl J Med. 2018. PMID: 30184460 No abstract available.
Effects of Bezafibrate on Outcome and Pruritus in Primary Biliary Cholangitis With Suboptimal Ursodeoxycholic Acid Response.
Reig A, Sesé P, Parés A. Reig A, et al. Am J Gastroenterol. 2018 Jan;113(1):49-55. doi: 10.1038/ajg.2017.287. Epub 2017 Oct 10. Am J Gastroenterol. 2018. PMID: 29016567
OBJECTIVES: Adding fibrates improves liver biochemistries in patients with primary biliary cholangitis (PBC) and suboptimal response to ursodeoxycholic acid (UDCA). ...Itching recurrence or worsening was observed after bezafibrate discontinuatio …
OBJECTIVES: Adding fibrates improves liver biochemistries in patients with primary biliary cholangitis (PBC) and …
Primary biliary cholangitis.
Parés A. Parés A. Med Clin (Barc). 2018 Sep 21;151(6):242-249. doi: 10.1016/j.medcli.2017.12.021. Epub 2018 Mar 9. Med Clin (Barc). 2018. PMID: 29526309 Review. English, Spanish.
Primary cholangitis (cirrhosis) is a chronic cholestatic disease with an unquestionable female predominance. It is characterised by inflammation of the small and medium size bile ducts, and can eventually progress to cirrhosis. ...The positivity of these anti
Primary cholangitis (cirrhosis) is a chronic cholestatic disease with an unquestionable female predominance. It is characteris
Work in Progress: Drugs in Development.
Webb GJ, Hirschfield GM. Webb GJ, et al. Clin Liver Dis. 2018 Aug;22(3):501-515. doi: 10.1016/j.cld.2018.03.004. Epub 2018 May 17. Clin Liver Dis. 2018. PMID: 30259849 Review.
Primary biliary cholangitis is an archetypal autoimmune disease that causes cholestasis, fibrosis, and liver failure. Ursodeoxycholic acid and obeticholic acid are approved for its treatment. ...We also consider the roles of bile acid reuptake inhibitors, nal
Primary biliary cholangitis is an archetypal autoimmune disease that causes cholestasis, fibrosis, and liver failure. U
Primary biliary cholangitis: Old and novel therapy.
Floreani A, Mangini C. Floreani A, et al. Eur J Intern Med. 2018 Jan;47:1-5. doi: 10.1016/j.ejim.2017.06.020. Epub 2017 Jun 29. Eur J Intern Med. 2018. PMID: 28669591 Review.
Primary biliary cholangitis (PBC), formerly called primary biliary cirrhosis, is a chronic cholestatic liver disease that progresses slowly to end-stage liver disease. ...The results of a randomized, double blind, phase 3 study of
Primary biliary cholangitis (PBC), formerly called primary biliary cirrhosis, is a chronic cholestatic
Improving prognosis in primary biliary cholangitis - Therapeutic options and strategy.
Harms MH, van Buuren HR, van der Meer AJ. Harms MH, et al. Best Pract Res Clin Gastroenterol. 2018 Jun-Aug;34-35:85-94. doi: 10.1016/j.bpg.2018.06.004. Epub 2018 Jun 14. Best Pract Res Clin Gastroenterol. 2018. PMID: 30343714 Review.
Overall survival in primary biliary cholangitis is diminished. As patients are often asymptomatic, the disease may silently progress towards cirrhosis and liver failure. ...Recent research, however, has identified a number of new therapeutic targets an …
Overall survival in primary biliary cholangitis is diminished. As patients are often asymptomatic, the disease may silently pr …
Primary biliary cirrhosis: Pathophysiology, clinical presentation and therapy.
Purohit T, Cappell MS. Purohit T, et al. World J Hepatol. 2015 May 8;7(7):926-41. doi: 10.4254/wjh.v7.i7.926. World J Hepatol. 2015. PMID: 25954476 Free PMC article. Review.
Primary biliary cirrhosis (PBC) is an autoimmune, slowly progressive, cholestatic, liver disease characterized by a triad of chronic cholestasis, circulating anti-mitochondrial antibodies (AMA), and characteristic liver biopsy findings of nonsup
Primary biliary cirrhosis (PBC) is an autoimmune, slowly progressive, cholestatic, liver disease characterized b
Primary biliary cholangitis: pathogenesis and therapeutic opportunities.
Gulamhusein AF, Hirschfield GM. Gulamhusein AF, et al. Nat Rev Gastroenterol Hepatol. 2020 Feb;17(2):93-110. doi: 10.1038/s41575-019-0226-7. Epub 2019 Dec 9. Nat Rev Gastroenterol Hepatol. 2020. PMID: 31819247 Review.
Primary biliary cholangitis is a chronic, seropositive and female-predominant inflammatory and cholestatic liver disease, which has a variable rate of progression towards biliary cirrhosis. Substantial progress has been made in patient risk stra
Primary biliary cholangitis is a chronic, seropositive and female-predominant inflammatory and cholestatic liver diseas
Additional fibrate treatment in UDCA-refractory PBC patients.
Chung SW, Lee JH, Kim MA, Leem G, Kim SW, Chang Y, Lee HY, Yoon JS, Park JY, Lee YB, Cho EJ, Yu SJ, Kim YJ, Yoon JH. Chung SW, et al. Liver Int. 2019 Sep;39(9):1776-1785. doi: 10.1111/liv.14165. Epub 2019 Jul 2. Liver Int. 2019. PMID: 31162879
BACKGROUND & AIMS: There is no proven treatment for ursodeoxycholic acid (UDCA)-refractory primary biliary cholangitis (PBC) other than obeticholic acid. ...The primary outcome was ALP normalization. Secondary outcomes included the development of cirrh
BACKGROUND & AIMS: There is no proven treatment for ursodeoxycholic acid (UDCA)-refractory primary biliary cholangitis (PB …
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