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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1940 1
1945 1
1946 4
1947 10
1948 5
1949 4
1950 13
1951 11
1952 14
1953 38
1954 21
1955 30
1956 36
1957 53
1958 64
1959 64
1960 70
1961 89
1962 116
1963 136
1964 166
1965 341
1966 462
1967 524
1968 761
1969 921
1970 855
1971 1029
1972 1225
1973 1505
1974 2103
1975 1952
1976 2077
1977 1981
1978 2160
1979 2507
1980 2733
1981 3168
1982 3625
1983 4052
1984 4594
1985 5457
1986 6106
1987 7425
1988 8826
1989 10963
1990 13524
1991 15326
1992 17026
1993 18411
1994 21224
1995 24017
1996 25336
1997 26795
1998 28311
1999 29832
2000 32255
2001 34083
2002 36986
2003 40684
2004 44541
2005 49237
2006 53206
2007 56057
2008 58366
2009 59519
2010 63246
2011 69612
2012 75445
2013 79485
2014 81877
2015 85233
2016 84004
2017 85473
2018 84883
2019 84147
2020 47004
2021 71
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1,464,019 results
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Page 1
The Evolution of Gene Expression in cis and trans.
Signor SA, Nuzhdin SV. Signor SA, et al. Trends Genet. 2018 Jul;34(7):532-544. doi: 10.1016/j.tig.2018.03.007. Epub 2018 Apr 18. Trends Genet. 2018. PMID: 29680748 Free PMC article. Review.
There is abundant variation in gene expression between individuals, populations, and species. The evolution of gene regulation and expression within and between species is thought to frequently contribute to adaptation. Yet considerable evidence sugges …
There is abundant variation in gene expression between individuals, populations, and species. The evolution of gene reg …
Sleep deprivation and gene expression.
da Costa Souza A, Ribeiro S. da Costa Souza A, et al. Curr Top Behav Neurosci. 2015;25:65-90. doi: 10.1007/7854_2014_360. Curr Top Behav Neurosci. 2015. PMID: 25646722 Review.
This chapter reviews studies in humans, rodents, and flies to address the various ways by which sleep deprivation affects gene expression in the nervous system, with a focus on genes related to neuronal plasticity, brain function, and cognition. However, the effects …
This chapter reviews studies in humans, rodents, and flies to address the various ways by which sleep deprivation affects gene exp
The core promoter: At the heart of gene expression.
Danino YM, Even D, Ideses D, Juven-Gershon T. Danino YM, et al. Biochim Biophys Acta. 2015 Aug;1849(8):1116-31. doi: 10.1016/j.bbagrm.2015.04.003. Epub 2015 Apr 28. Biochim Biophys Acta. 2015. PMID: 25934543 Review.
The identities of different cells and tissues in multicellular organisms are determined by tightly controlled transcriptional programs that enable accurate gene expression. The mechanisms that regulate gene expression comprise diverse multiplayer molec …
The identities of different cells and tissues in multicellular organisms are determined by tightly controlled transcriptional programs that …
Gene expression variability: the other dimension in transcriptome analysis.
de Jong TV, Moshkin YM, Guryev V. de Jong TV, et al. Physiol Genomics. 2019 May 1;51(5):145-158. doi: 10.1152/physiolgenomics.00128.2018. Epub 2019 Mar 15. Physiol Genomics. 2019. PMID: 30875273
However, it is becoming apparent that the biological variation in gene expression might be an important molecular phenotype that can affect physiological parameters. In this review we explore the recent literature on technical and biological variability in gene
However, it is becoming apparent that the biological variation in gene expression might be an important molecular phenotype th …
Gene Expression Correlated with Severe Asthma Characteristics Reveals Heterogeneous Mechanisms of Severe Disease.
Modena BD, Bleecker ER, Busse WW, Erzurum SC, Gaston BM, Jarjour NN, Meyers DA, Milosevic J, Tedrow JR, Wu W, Kaminski N, Wenzel SE. Modena BD, et al. Am J Respir Crit Care Med. 2017 Jun 1;195(11):1449-1463. doi: 10.1164/rccm.201607-1407OC. Am J Respir Crit Care Med. 2017. PMID: 27984699 Free PMC article.
Gene expression studies of bronchial epithelial cells in individuals with asthma have provided biological insight and underscored possible mechanistic differences between individuals. ...T1 inflammation, especially when associated with increased T2 gene ex
Gene expression studies of bronchial epithelial cells in individuals with asthma have provided biological insight and undersco
A Growing Toolbox to Image Gene Expression in Single Cells: Sensitive Approaches for Demanding Challenges.
Pichon X, Lagha M, Mueller F, Bertrand E. Pichon X, et al. Mol Cell. 2018 Aug 2;71(3):468-480. doi: 10.1016/j.molcel.2018.07.022. Mol Cell. 2018. PMID: 30075145 Free article. Review.
We present how they advanced our understanding of gene expression heterogeneity and bursting, as well as the spatiotemporal aspects of splicing, translation, and RNA decay. These insights yield a dynamic and stochastic view of gene expression in single …
We present how they advanced our understanding of gene expression heterogeneity and bursting, as well as the spatiotemporal as …
Cell-type-specific programs for activity-regulated gene expression.
Gray JM, Spiegel I. Gray JM, et al. Curr Opin Neurobiol. 2019 Jun;56:33-39. doi: 10.1016/j.conb.2018.11.001. Epub 2018 Dec 4. Curr Opin Neurobiol. 2019. PMID: 30529822 Review.
Experience leaves a lasting mark on neural circuit function in part through activity-regulated gene (ARG) expression. New genome wide approaches have revealed that ARG programs are highly cell-type-specific, raising the possibility that they mediate different forms …
Experience leaves a lasting mark on neural circuit function in part through activity-regulated gene (ARG) expression. New geno …
Systematic identification of human housekeeping genes possibly useful as references in gene expression studies.
Caracausi M, Piovesan A, Antonaros F, Strippoli P, Vitale L, Pelleri MC. Caracausi M, et al. Mol Med Rep. 2017 Sep;16(3):2397-2410. doi: 10.3892/mmr.2017.6944. Epub 2017 Jul 6. Mol Med Rep. 2017. PMID: 28713914 Free PMC article.
Recent advancements in the quality and completeness of human expression microarray data and in their statistical analysis may provide new clues toward the quantitative standardization of human gene expression studies in biology and medicine, both cross‑ and w …
Recent advancements in the quality and completeness of human expression microarray data and in their statistical analysis may provide …
In vivo methods for acute modulation of gene expression in the central nervous system.
Cwetsch AW, Pinto B, Savardi A, Cancedda L. Cwetsch AW, et al. Prog Neurobiol. 2018 Sep;168:69-85. doi: 10.1016/j.pneurobio.2018.04.008. Epub 2018 Apr 22. Prog Neurobiol. 2018. PMID: 29694844 Free PMC article. Review.
Accurate and timely expression of specific genes guarantees the healthy development and function of the brain. Indeed, variations in the correct amount or timing of gene expression lead to improper development and/or pathological conditions. Almost forty year …
Accurate and timely expression of specific genes guarantees the healthy development and function of the brain. Indeed, variations in …
Intrinsic Dynamics of a Human Gene Reveal the Basis of Expression Heterogeneity.
Rodriguez J, Ren G, Day CR, Zhao K, Chow CC, Larson DR. Rodriguez J, et al. Cell. 2019 Jan 10;176(1-2):213-226.e18. doi: 10.1016/j.cell.2018.11.026. Epub 2018 Dec 13. Cell. 2019. PMID: 30554876 Free PMC article.
To understand the relationship between these two phenomena and the dynamic regulation of genes in response to upstream signals, we describe the use of live-cell RNA imaging coupled with Hi-C measurements and dissect the endogenous regulation of the estrogen-responsive TFF1 gen
To understand the relationship between these two phenomena and the dynamic regulation of genes in response to upstream signals, we describe …
1,464,019 results
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