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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 4
1964 4
1965 1
1968 1
1969 1
1970 2
1971 5
1972 2
1973 3
1974 5
1975 10
1976 7
1977 6
1978 11
1979 10
1980 6
1981 6
1982 11
1983 13
1984 12
1985 14
1986 9
1987 9
1988 16
1989 14
1990 15
1991 16
1992 3
1993 7
1994 13
1995 14
1996 12
1997 15
1998 9
1999 8
2000 4
2001 8
2002 11
2003 4
2004 9
2005 7
2006 7
2007 3
2008 3
2009 5
2010 10
2011 6
2012 7
2013 11
2014 9
2015 11
2016 9
2017 22
2018 6
2019 8
2020 8
2021 4
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446 results
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Page 1
Hepatic transport systems.
Ferenci P, Zollner G, Trauner M. Ferenci P, et al. J Gastroenterol Hepatol. 2002 Feb;17 Suppl:S105-12. doi: 10.1046/j.1440-1746.17.s1.15.x. J Gastroenterol Hepatol. 2002. PMID: 12000597 Review.
The identification of the genes responsible for various genetic liver disorders lead to a better understanding of basic physiology of hepatic transport systems. In this review we focus on transport systems involved in the generation of bile and in the mainten …
The identification of the genes responsible for various genetic liver disorders lead to a better understanding of basic physiology of hep
FABP1 controls hepatic transport and biotransformation of delta(9)-THC.
Elmes MW, Prentis LE, McGoldrick LL, Giuliano CJ, Sweeney JM, Joseph OM, Che J, Carbonetti GS, Studholme K, Deutsch DG, Rizzo RC, Glynn SE, Kaczocha M. Elmes MW, et al. Sci Rep. 2019 May 20;9(1):7588. doi: 10.1038/s41598-019-44108-3. Sci Rep. 2019. PMID: 31110286 Free PMC article.
The lipophilic nature of cannabinoids necessitates mechanism(s) to facilitate their intracellular transport to metabolic enzymes. Here, we test the central hypothesis that liver-type fatty acid binding protein (FABP1) mediates phytocannabinoid transport and subseque …
The lipophilic nature of cannabinoids necessitates mechanism(s) to facilitate their intracellular transport to metabolic enzymes. Her …
The complexities of hepatic drug transport: current knowledge and emerging concepts.
Chandra P, Brouwer KL. Chandra P, et al. Pharm Res. 2004 May;21(5):719-35. doi: 10.1023/b:pham.0000026420.79421.8f. Pharm Res. 2004. PMID: 15180326 Review.
Recently, hepatic transport processes have been recognized as important determinants of drug disposition. Therefore, it is not surprising that characterization of the hepatic transport and biliary excretion properties of potential drug candidates is an …
Recently, hepatic transport processes have been recognized as important determinants of drug disposition. Therefore, it is not …
Quantitative PET of liver functions.
Keiding S, Sørensen M, Frisch K, Gormsen LC, Munk OL. Keiding S, et al. Am J Nucl Med Mol Imaging. 2018 Apr 25;8(2):73-85. eCollection 2018. Am J Nucl Med Mol Imaging. 2018. PMID: 29755841 Free PMC article. Review.
Standard-uptake-value (SUV) from a static liver (18)F-FDGal PET/CT scan can replace K(met) and is currently used clinically. 2) Dynamic liver PET/CT in humans with (11)C-palmitate and with the conjugated bile acid tracer [N-methyl-(11)C]cholylsarcosine ((11)C-CSar) can distinguis …
Standard-uptake-value (SUV) from a static liver (18)F-FDGal PET/CT scan can replace K(met) and is currently used clinically. 2) Dynamic live …
Quantitative Kinetic Models from Intravital Microscopy: A Case Study Using Hepatic Transport.
Tavakoli M, Tsekouras K, Day R, Dunn KW, Pressé S. Tavakoli M, et al. J Phys Chem B. 2019 Aug 29;123(34):7302-7312. doi: 10.1021/acs.jpcb.9b04729. Epub 2019 Aug 15. J Phys Chem B. 2019. PMID: 31298856 Free PMC article.
The liver performs critical physiological functions, including metabolizing and removing substances, such as toxins and drugs, from the bloodstream. Hepatotoxicity itself is intimately linked to abnormal hepatic transport, and hepatotoxicity remains the primary reas …
The liver performs critical physiological functions, including metabolizing and removing substances, such as toxins and drugs, from the bloo …
Using quantitative intravital multiphoton microscopy to dissect hepatic transport in rats.
Dunn KW, Ryan JC. Dunn KW, et al. Methods. 2017 Sep 1;128:40-51. doi: 10.1016/j.ymeth.2017.04.015. Epub 2017 Apr 21. Methods. 2017. PMID: 28434905 Free article.
Hepatic solute transport is a complex process whose disruption is associated with liver disease and drug-induced liver injury. ...Here we present an overview of the use of fluorescence microscopy for studies of hepatic transport in living animals, and
Hepatic solute transport is a complex process whose disruption is associated with liver disease and drug-induced liver injury.
Altered Hepatic Transport by Fetal Arsenite Exposure in Diet-Induced Fatty Liver Disease.
Ditzel EJ, Li H, Foy CE, Perrera AB, Parker P, Renquist BJ, Cherrington NJ, Camenisch TD. Ditzel EJ, et al. J Biochem Mol Toxicol. 2016 Jul;30(7):321-30. doi: 10.1002/jbt.21796. Epub 2016 Feb 18. J Biochem Mol Toxicol. 2016. PMID: 26890134 Free PMC article.
This study examines the effects of arsenite potentiated diet-induced fatty liver disease on hepatic transport in male mice. Changes were detected for Mrp2/3/4 hepatic transporter gene expression as well as for Oatp1a4/2b1/1b2. ...These data indicate that deve …
This study examines the effects of arsenite potentiated diet-induced fatty liver disease on hepatic transport in male mice. Ch …
Roles of Hepatic Drug Transporters in Drug Disposition and Liver Toxicity.
Pan G. Pan G. Adv Exp Med Biol. 2019;1141:293-340. doi: 10.1007/978-981-13-7647-4_6. Adv Exp Med Biol. 2019. PMID: 31571168 Review.
According to their functions, hepatic transporters can be roughly divided into influx and efflux transporters, translocating specific molecules from blood into hepatic cytosol and mediating the excretion of drugs and metabolites from hepatic cytosol to blood …
According to their functions, hepatic transporters can be roughly divided into influx and efflux transporters, translocating specific …
Abnormal hepatic transport of indocyanine green in Gilbert's syndrome.
Martin JF, Vierling JM, Wolkoff AW, Scharschmidt BF, Vergalla J, Waggoner JG, Berk PD. Martin JF, et al. Gastroenterology. 1976 Mar;70(3):385-91. Gastroenterology. 1976. PMID: 814028 Review.
The patients were further classified into 3 subgroups, based on patterns of sulfobromophthalein (BSP) kinetics, as follows: GS I (15 patients) had normal BSP metabolism; GS II (5 patients) had a defect in BSP metabolism beyond the stage of initial hepatic uptake; and GS II …
The patients were further classified into 3 subgroups, based on patterns of sulfobromophthalein (BSP) kinetics, as follows: GS I (15 patient …
Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein.
de Waart DR, Häusler S, Vlaming ML, Kunne C, Hänggi E, Gruss HJ, Oude Elferink RP, Stieger B. de Waart DR, et al. J Pharmacol Exp Ther. 2010 Jul;334(1):78-86. doi: 10.1124/jpet.110.166991. Epub 2010 Apr 13. J Pharmacol Exp Ther. 2010. PMID: 20388726
In Abcc2(-/-) mice biliary excretion of CLF was strongly reduced compared with wild-type mice. This resulted in a much higher hepatic retention of CLF in Abcc2(-/-) versus wild-type mice: 64 versus 1% of the administered dose (2 h after administration). ...Our conclusion i …
In Abcc2(-/-) mice biliary excretion of CLF was strongly reduced compared with wild-type mice. This resulted in a much higher hepatic
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