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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
2000 3
2001 5
2002 22
2003 33
2004 84
2005 132
2006 143
2007 168
2008 228
2009 299
2010 313
2011 341
2012 316
2013 383
2014 426
2015 409
2016 410
2017 446
2018 464
2019 434
2020 346
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4,642 results
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Page 1
Hepcidin and the BMP-SMAD pathway: An unexpected liaison.
Silvestri L, Nai A, Dulja A, Pagani A. Silvestri L, et al. Vitam Horm. 2019;110:71-99. doi: 10.1016/bs.vh.2019.01.004. Epub 2019 Feb 10. Vitam Horm. 2019. PMID: 30798817 Review.
Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of infla …
Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) an …
Hepcidin.
Agarwal AK, Yee J. Agarwal AK, et al. Adv Chronic Kidney Dis. 2019 Jul;26(4):298-305. doi: 10.1053/j.ackd.2019.04.005. Adv Chronic Kidney Dis. 2019. PMID: 31477260 Review.
Hepcidin itself is regulated by the supply of iron, the need for erythropoiesis, and the state of inflammation. Alterations in hepcidin levels are associated with restricted erythropoiesis, anemia, and iron overload. ...This knowledge has also unlocked unique opport
Hepcidin itself is regulated by the supply of iron, the need for erythropoiesis, and the state of inflammation. Alterations in hep
Iron homeostasis during pregnancy.
Fisher AL, Nemeth E. Fisher AL, et al. Am J Clin Nutr. 2017 Dec;106(Suppl 6):1567S-1574S. doi: 10.3945/ajcn.117.155812. Epub 2017 Oct 25. Am J Clin Nutr. 2017. PMID: 29070542 Free PMC article. Review.
The mechanism of maternal hepcidin suppression in pregnancy is unknown, but hepcidin regulation by the known stimuli (i.e., iron, erythropoietic activity, and inflammation) appears to be preserved during pregnancy. Inappropriately increased maternal hepcidin
The mechanism of maternal hepcidin suppression in pregnancy is unknown, but hepcidin regulation by the known stimuli (i.e., ir …
Hepcidin regulation in the anemia of inflammation.
Wang CY, Babitt JL. Wang CY, et al. Curr Opin Hematol. 2016 May;23(3):189-97. doi: 10.1097/MOH.0000000000000236. Curr Opin Hematol. 2016. PMID: 26886082 Free PMC article. Review.
RECENT FINDINGS: IL-6 is a primary driver for hepcidin induction in many models of anemia of inflammation, but the SMAD1/5/8 pathway also contributes, likely via Activin B and SMAD-STAT3 interactions at the hepcidin promoter. Hepcidin has an important functio …
RECENT FINDINGS: IL-6 is a primary driver for hepcidin induction in many models of anemia of inflammation, but the SMAD1/5/8 pathway …
Hepcidin: Homeostasis and Diseases Related to Iron Metabolism.
Reichert CO, da Cunha J, Levy D, Maselli LMF, Bydlowski SP, Spada C. Reichert CO, et al. Acta Haematol. 2017;137(4):220-236. doi: 10.1159/000471838. Epub 2017 May 18. Acta Haematol. 2017. PMID: 28514781 Review.
Genetic alterations influence the serum hepcidin concentration, which can lead to an iron overload in tissues, as observed in haemochromatosis, in which serum hepcidin or defective hepcidin synthesis is observed. ...To date, there is no available drug to inhi …
Genetic alterations influence the serum hepcidin concentration, which can lead to an iron overload in tissues, as observed in haemoch …
Regulators of hepcidin expression.
Roth MP, Meynard D, Coppin H. Roth MP, et al. Vitam Horm. 2019;110:101-129. doi: 10.1016/bs.vh.2019.01.005. Epub 2019 Feb 2. Vitam Horm. 2019. PMID: 30798807 Review.
This regulation is mediated by the hepatic hormone hepcidin. Hepcidin also controls iron release from macrophages that recycle iron and from hepatocytes that store iron. ...Dysregulation of hepcidin production contributes to the pathogenesis of many iron diso …
This regulation is mediated by the hepatic hormone hepcidin. Hepcidin also controls iron release from macrophages that recycle …
Regulation of the Iron Homeostatic Hormone Hepcidin.
Sangkhae V, Nemeth E. Sangkhae V, et al. Adv Nutr. 2017 Jan 17;8(1):126-136. doi: 10.3945/an.116.013961. Print 2017 Jan. Adv Nutr. 2017. PMID: 28096133 Free PMC article. Review.
Iron absorption is regulated by the hepatic peptide hormone hepcidin. Hepcidin also controls iron release from cells that recycle or store iron, thus regulating plasma iron concentrations. ...This review summarizes our current understanding of the molecular mechanis …
Iron absorption is regulated by the hepatic peptide hormone hepcidin. Hepcidin also controls iron release from cells that recy …
Hepcidin-ferroportin axis in health and disease.
Ginzburg YZ. Ginzburg YZ. Vitam Horm. 2019;110:17-45. doi: 10.1016/bs.vh.2019.01.002. Epub 2019 Feb 8. Vitam Horm. 2019. PMID: 30798811 Review.
Aberrantly increased hepcidin leads to systemic iron deficiency and/or iron restricted erythropoiesis. Furthermore, insufficiently elevated hepcidin occurs in multiple diseases associated with iron overload. ...In this chapter, we present an overview of and rational …
Aberrantly increased hepcidin leads to systemic iron deficiency and/or iron restricted erythropoiesis. Furthermore, insufficiently el …
Hepcidin: A key regulator of iron.
Saneela S, Iqbal R, Raza A, Qamar MF. Saneela S, et al. J Pak Med Assoc. 2019 Aug;69(8):1170-1175. J Pak Med Assoc. 2019. PMID: 31431773 Free article. Review.
Hepcidin is a 25 amino acid long chain peptide. Inflammation or iron overload greatly stimulate production of hepcidin by hepatocytes. ...Moreover, hepcidin plays a key role in different types of anaemia, mainly anaemia of inflammation in which concentration
Hepcidin is a 25 amino acid long chain peptide. Inflammation or iron overload greatly stimulate production of hepcidin by hepa
Systemic iron homeostasis.
Ganz T. Ganz T. Physiol Rev. 2013 Oct;93(4):1721-41. doi: 10.1152/physrev.00008.2013. Physiol Rev. 2013. PMID: 24137020 Free article. Review.
Because iron losses are comparatively very small, iron absorption and its regulation by hepcidin and ferroportin determine total body iron content. ...Hepcidin and ferroportin also play a role in host defense and inflammation, and hepcidin synthesis is induce …
Because iron losses are comparatively very small, iron absorption and its regulation by hepcidin and ferroportin determine total body …
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