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2002 1
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2005 1
2006 3
2007 2
2008 1
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2011 3
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2014 11
2015 7
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2017 9
2018 5
2019 3
2020 6
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Page 1
The Role of Intestinal Alkaline Phosphatase in Inflammatory Disorders of Gastrointestinal Tract.
Bilski J, Mazur-Bialy A, Wojcik D, Zahradnik-Bilska J, Brzozowski B, Magierowski M, Mach T, Magierowska K, Brzozowski T. Bilski J, et al. Mediators Inflamm. 2017;2017:9074601. doi: 10.1155/2017/9074601. Epub 2017 Feb 21. Mediators Inflamm. 2017. PMID: 28316376 Free PMC article. Review.
Over the past few years, the role of intestinal alkaline phosphatase (IAP) as a crucial mucosal defence factor essential for maintaining gut homeostasis has been established. ...Diminished activity of IAP could increase the risk of disease through changes in …
Over the past few years, the role of intestinal alkaline phosphatase (IAP) as a crucial mucosal defence factor essentia …
Effects of intestinal alkaline phosphatase on intestinal barrier function in a cecal ligation and puncture (CLP)-induced mouse model for sepsis.
Plaeke P, De Man JG, Smet A, Malhotra-Kumar S, Pintelon I, Timmermans JP, Nullens S, Jorens PG, Hubens G, De Winter BY. Plaeke P, et al. Neurogastroenterol Motil. 2020 Mar;32(3):e13754. doi: 10.1111/nmo.13754. Epub 2019 Nov 21. Neurogastroenterol Motil. 2020. PMID: 31751495
BACKGROUND: Sepsis is a severe pathological condition associated with systemic inflammation, intestinal inflammation, and gastrointestinal barrier dysfunction. Intestinal alkaline phosphatase (IAP) has been demonstrated to detoxify lipopolysaccharid
BACKGROUND: Sepsis is a severe pathological condition associated with systemic inflammation, intestinal inflammation, and gastrointes …
Intestinal alkaline phosphatase and sodium butyrate may be beneficial in attenuating LPS-induced intestinal inflammation.
Melo AD, Silveira H, Bortoluzzi C, Lara LJ, Garbossa CA, Preis G, Costa LB, Rostagno MH. Melo AD, et al. Genet Mol Res. 2016 Oct 17;15(4). doi: 10.4238/gmr15048875. Genet Mol Res. 2016. PMID: 27813594
In this study, we evaluated the effect of intestinal alkaline phosphatase (IAP) and sodium butyrate (NaBu) on lipopolysaccharide (LPS)-induced intestinal inflammation. Intestinal alkaline phosphatase and RelA/p65 (NF-kappaB) …
In this study, we evaluated the effect of intestinal alkaline phosphatase (IAP) and sodium butyrate (NaBu) on lipopo
Curcumin and chronic kidney disease (CKD): major mode of action through stimulating endogenous intestinal alkaline phosphatase.
Ghosh SS, Gehr TW, Ghosh S. Ghosh SS, et al. Molecules. 2014 Dec 2;19(12):20139-56. doi: 10.3390/molecules191220139. Molecules. 2014. PMID: 25474287 Free PMC article. Review.
Various enzymes, transcription factors, growth factors modulate production and action of inflammatory molecules; curcumin can blunt the generation and action of these inflammatory molecules and ameliorate CKD as well as associated inflammatory disorders. Recent studies have shown …
Various enzymes, transcription factors, growth factors modulate production and action of inflammatory molecules; curcumin can blunt the gene …
Interplay between intestinal alkaline phosphatase, diet, gut microbes and immunity.
Estaki M, DeCoffe D, Gibson DL. Estaki M, et al. World J Gastroenterol. 2014 Nov 14;20(42):15650-6. doi: 10.3748/wjg.v20.i42.15650. World J Gastroenterol. 2014. PMID: 25400448 Free PMC article. Review.
Intestinal alkaline phosphatase (IAP) plays an essential role in intestinal homeostasis and health through interactions with the resident microbiota, diet and the gut. ...The purpose of this review is to highlight the essential characteristics of IAP i
Intestinal alkaline phosphatase (IAP) plays an essential role in intestinal homeostasis and health through inter
Sequence and functional analysis of intestinal alkaline phosphatase from Lateolabrax maculatus.
Wu M, Wang J, Wang Z, Zhao J, Hu Y, Chen X. Wu M, et al. Fish Physiol Biochem. 2017 Dec;43(6):1463-1476. doi: 10.1007/s10695-017-0385-9. Epub 2017 May 28. Fish Physiol Biochem. 2017. PMID: 28551866
Alkaline phosphatases (Alps) belong to a class of phosphate transferases that dephosphorylate lipopolysaccharide (LPS), adenosine triphosphate, and nucleotides. In this study, a 1874-base pair (bp) intestinal alp cDNA sequence was cloned from Lateolabrax macu
Alkaline phosphatases (Alps) belong to a class of phosphate transferases that dephosphorylate lipopolysaccharide (LPS), adenos
Intestine-specific expression of human chimeric intestinal alkaline phosphatase attenuates Western diet-induced barrier dysfunction and glucose intolerance.
Ghosh SS, He H, Wang J, Korzun W, Yannie PJ, Ghosh S. Ghosh SS, et al. Physiol Rep. 2018 Jul;6(14):e13790. doi: 10.14814/phy2.13790. Physiol Rep. 2018. PMID: 30058275 Free PMC article.
Intestinal epithelial cell derived alkaline phosphatase (IAP) dephosphorylates/detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the gut lumen. ...This chimeric human IAP contains domains from human IAP and human placental alkaline p
Intestinal epithelial cell derived alkaline phosphatase (IAP) dephosphorylates/detoxifies bacterial endotoxin lipopo
Loss of Intestinal Alkaline Phosphatase Leads to Distinct Chronic Changes in Bone Phenotype.
Kuehn F, Adiliaghdam F, Hamarneh SR, Vasan R, Liu E, Liu Y, Ramirez JM, Hoda RS, Munoz AR, Ko FC, Armanini M, Brooks DJ, Bouxsein ML, Demay MB, Hodin RA. Kuehn F, et al. J Surg Res. 2018 Dec;232:325-331. doi: 10.1016/j.jss.2018.06.061. Epub 2018 Jul 18. J Surg Res. 2018. PMID: 30463736
The microbiome and gut-derived mediators are thought to impact upon bone metabolism, and administration of probiotics has been shown to have beneficial effects in bone. The gut brush border enzyme intestinal alkaline phosphatase (IAP) plays an important role …
The microbiome and gut-derived mediators are thought to impact upon bone metabolism, and administration of probiotics has been shown to have …
Intestinal alkaline phosphatase: novel functions and protective effects.
Lallès JP. Lallès JP. Nutr Rev. 2014 Feb;72(2):82-94. doi: 10.1111/nure.12082. Epub 2013 Dec 9. Nutr Rev. 2014. PMID: 24506153 Review.
Important protective roles of intestinal alkaline phosphatase (IAP)--including regulation of intestinal surface pH, absorption of lipids, detoxification of free nucleotides and bacterial lipopolysaccharide, attenuation of intestinal infla …
Important protective roles of intestinal alkaline phosphatase (IAP)--including regulation of intestinal surface …
Ontogeny of alkaline phosphatase activity in infant intestines and breast milk.
Yang Y, Rader E, Peters-Carr M, Bent RC, Smilowitz JT, Guillemin K, Rader B. Yang Y, et al. BMC Pediatr. 2019 Jan 3;19(1):2. doi: 10.1186/s12887-018-1379-1. BMC Pediatr. 2019. PMID: 30606146 Free PMC article.
The metalloenzyme alkaline phosphatase (ALP) has been shown to reduce lipopolysaccharide-mediated inflammation. ...To explore the possibility that the human premature neonatal intestine has a paucity of alkaline phosphatase activity, we measured …
The metalloenzyme alkaline phosphatase (ALP) has been shown to reduce lipopolysaccharide-mediated inflammation. ...To e …
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