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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 12
1947 17
1948 11
1949 8
1950 17
1951 16
1952 10
1953 22
1954 13
1955 19
1956 27
1957 30
1958 29
1959 40
1960 56
1961 87
1962 94
1963 92
1964 129
1965 138
1966 153
1967 201
1968 235
1969 298
1970 334
1971 473
1972 704
1973 787
1974 804
1975 724
1976 632
1977 549
1978 486
1979 524
1980 594
1981 624
1982 630
1983 630
1984 772
1985 873
1986 922
1987 834
1988 844
1989 984
1990 1099
1991 1227
1992 1405
1993 1389
1994 1699
1995 1737
1996 1858
1997 2035
1998 2393
1999 2610
2000 2886
2001 3263
2002 3673
2003 4060
2004 4445
2005 4859
2006 5306
2007 5526
2008 5762
2009 6114
2010 6520
2011 6877
2012 7277
2013 7443
2014 7404
2015 7565
2016 7195
2017 7205
2018 7041
2019 6626
2020 3652
2021 2
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139,890 results
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Page 1
Metalloproteinases in atherosclerosis.
Johnson JL. Johnson JL. Eur J Pharmacol. 2017 Dec 5;816:93-106. doi: 10.1016/j.ejphar.2017.09.007. Epub 2017 Sep 9. Eur J Pharmacol. 2017. PMID: 28893577 Review.
Members of the metalloproteinase family, especially matrix metalloproteinases (MMPs), and their endogenous tissue inhibitors (TIMPs) have been suggested to perform complex dual roles during late-stage progression and rupture of atherosclerotic plaques. ...This revie …
Members of the metalloproteinase family, especially matrix metalloproteinases (MMPs), and their endogenous tissue inhibitors ( …
The role of matrix metalloproteinases in osteoarthritis pathogenesis: An updated review.
Mehana EE, Khafaga AF, El-Blehi SS. Mehana EE, et al. Life Sci. 2019 Oct 1;234:116786. doi: 10.1016/j.lfs.2019.116786. Epub 2019 Aug 22. Life Sci. 2019. PMID: 31445934 Review.
A key enzyme responsible for these degenerative changes in cartilage is matrix metalloproteinase-13 (MMP-13), which is thought to be a major contributor to the degenerative process occurring during OA pathogenesis. ...
A key enzyme responsible for these degenerative changes in cartilage is matrix metalloproteinase-13 (MMP-13), which is thought to be …
A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential.
Gobin E, Bagwell K, Wagner J, Mysona D, Sandirasegarane S, Smith N, Bai S, Sharma A, Schleifer R, She JX. Gobin E, et al. BMC Cancer. 2019 Jun 14;19(1):581. doi: 10.1186/s12885-019-5768-0. BMC Cancer. 2019. PMID: 31200666 Free PMC article.
Multiple MMPs possess AUC's > 0.9 in more than one cancer. However, survival analyses suggest that the prognostic value of MMPs is limited to clear cell renal carcinoma. ...
Multiple MMPs possess AUC's > 0.9 in more than one cancer. However, survival analyses suggest that the prognostic value of MMPs is …
Role of meprin metalloproteinases in cytokine processing and inflammation.
Herzog C, Haun RS, Kaushal GP. Herzog C, et al. Cytokine. 2019 Feb;114:18-25. doi: 10.1016/j.cyto.2018.11.032. Epub 2018 Dec 20. Cytokine. 2019. PMID: 30580156 Free PMC article. Review.
Smoking confounds the periodontal diagnostics using saliva biomarkers.
Lahdentausta L, Paju S, Mäntylä P, Buhlin K, Pietiäinen M, Tervahartiala T, Nieminen MS, Sinisalo J, Sorsa T, Pussinen PJ. Lahdentausta L, et al. J Periodontol. 2019 May;90(5):475-483. doi: 10.1002/JPER.18-0545. Epub 2018 Dec 14. J Periodontol. 2019. PMID: 30447005
We investigated the effect of smoking on salivary periodontal biomarkers, matrix metalloproteinase (MMP)-8, MMP-9, tissue inhibitor of metalloproteinase (TIMP)-1 and myeloperoxidase (MPO). ...
We investigated the effect of smoking on salivary periodontal biomarkers, matrix metalloproteinase (MMP)-8, MMP-9, tissue inhibitor o …
Metalloproteases.
Nagase H. Nagase H. Curr Protoc Protein Sci. 2001 Aug;Chapter 21:Unit 21.4. doi: 10.1002/0471140864.ps2104s24. Curr Protoc Protein Sci. 2001. PMID: 18429165 Review.
Metalloproteases (metallopeptidases) are composed of a diverse group of endopeptidases and exopeptidases. Because metalloproteases play key roles in many normal biological processes, their aberrant activities have been implicated in diseases such as arthritis, cance
Metalloproteases (metallopeptidases) are composed of a diverse group of endopeptidases and exopeptidases. Because metalloproteases
Activity-based probes for the proteomic profiling of metalloproteases.
Saghatelian A, Jessani N, Joseph A, Humphrey M, Cravatt BF. Saghatelian A, et al. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10000-5. doi: 10.1073/pnas.0402784101. Epub 2004 Jun 25. Proc Natl Acad Sci U S A. 2004. PMID: 15220480 Free PMC article.
Metalloproteases (MPs) are a large and diverse class of enzymes implicated in numerous physiological and pathological processes, including tissue remodeling, peptide hormone processing, and cancer. ...Interestingly, the matrix metalloproteinase inhibitor GM6001 (ilo
Metalloproteases (MPs) are a large and diverse class of enzymes implicated in numerous physiological and pathological processes, incl
Handling Metalloproteinases.
Fridrich S, Karmilin K, Stöcker W. Fridrich S, et al. Curr Protoc Protein Sci. 2016 Feb 2;83:21.16.1-21.16.20. doi: 10.1002/0471140864.ps2116s83. Curr Protoc Protein Sci. 2016. PMID: 26836407 Review.
This arrangement suggests that the physiological pH optimum of most metalloproteinases is in the neutral range. In addition to their catalytic metal ion, many metalloproteinases contain additional transition metal or alkaline earth ions, which are structurally impor …
This arrangement suggests that the physiological pH optimum of most metalloproteinases is in the neutral range. In addition to their …
Plasma Levels and Tissue Expression of Selected Cytokines, Metalloproteinases and Tissue Inhibitors in Patients With Cervical Cancer.
Sidorkiewicz I, Piskór B, Dąbrowska E, Guzińska-Ustymowicz K, Pryczynicz A, Zbucka-Krętowska M, Ławicki S. Sidorkiewicz I, et al. Anticancer Res. 2019 Nov;39(11):6403-6412. doi: 10.21873/anticanres.13854. Anticancer Res. 2019. PMID: 31704874
BACKGROUND: Cytokines, metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) take part in many processes involved in tumor progression and invasion such as degradation of the extracellular matrix, influence on immune cells associated with tumor tissue, and angiogen …
BACKGROUND: Cytokines, metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) take part in many processes involved in tumor pr …
Arterial Aging, Metalloproteinase Regulation, and the Potential of Resistance Exercise.
Knox A. Knox A. Curr Cardiol Rev. 2018;14(4):227-232. doi: 10.2174/1573403X14666180801153801. Curr Cardiol Rev. 2018. PMID: 30068282 Free PMC article. Review.
Matrix metalloproteinases are a group of extremely active enzymes that regulate the age-associated structural changes of the vasculature which has been regarded as the hallmark of arterial aging. ...This review provides a brief synopsis of the matrix metalloproteinase
Matrix metalloproteinases are a group of extremely active enzymes that regulate the age-associated structural changes of the vasculat …
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