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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1955 2
1980 1
1985 1
1989 2
1991 3
1995 1
1996 1
1997 4
1998 8
1999 17
2000 12
2001 18
2002 28
2003 22
2004 29
2005 40
2006 40
2007 57
2008 44
2009 47
2010 63
2011 59
2012 66
2013 91
2014 80
2015 73
2016 74
2017 82
2018 79
2019 76
2020 68
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1,052 results
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Page 1
Milk thistle in liver diseases: past, present, future.
Abenavoli L, Capasso R, Milic N, Capasso F. Abenavoli L, et al. Phytother Res. 2010 Oct;24(10):1423-32. doi: 10.1002/ptr.3207. Phytother Res. 2010. PMID: 20564545 Review.
Silybum marianum or milk thistle (MT) is the most well-researched plant in the treatment of liver disease. The active complex of MT is a lipophilic extract from the seeds of the plant and is composed of three isomer flavonolignans (silybin, silydianin, and silychris …
Silybum marianum or milk thistle (MT) is the most well-researched plant in the treatment of liver disease. The active complex …
Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases.
Abenavoli L, Izzo AA, Milić N, Cicala C, Santini A, Capasso R. Abenavoli L, et al. Phytother Res. 2018 Nov;32(11):2202-2213. doi: 10.1002/ptr.6171. Epub 2018 Aug 6. Phytother Res. 2018. PMID: 30080294 Review.
Milk thistle (MT; Silybum marianum), a member of the Asteraceae family, is a therapeutic herb with a 2,000-year history of use. ...
Milk thistle (MT; Silybum marianum), a member of the Asteraceae family, is a therapeutic herb with a 2,000-year history of use
Silybin, a Major Bioactive Component of Milk Thistle (Silybum marianum L. Gaernt.)-Chemistry, Bioavailability, and Metabolism.
Bijak M. Bijak M. Molecules. 2017 Nov 10;22(11):1942. doi: 10.3390/molecules22111942. Molecules. 2017. PMID: 29125572 Free PMC article. Review.
Milk thistle (Silybum marianum) is a medicinal plant that has been used for thousands of years as a remedy for a variety of ailments. ...
Milk thistle (Silybum marianum) is a medicinal plant that has been used for thousands of years as a remedy for a variety of ai
Silybum marianum (milk thistle) and its main constituent, silymarin, as a potential therapeutic plant in metabolic syndrome: A review.
Tajmohammadi A, Razavi BM, Hosseinzadeh H. Tajmohammadi A, et al. Phytother Res. 2018 Oct;32(10):1933-1949. doi: 10.1002/ptr.6153. Epub 2018 Jul 17. Phytother Res. 2018. PMID: 30015401 Review.
Silymarin is the main component of S. marianum and derived from fruits and seeds of S. marianum (milk thistle). S. marianum has been found to exhibit antioxidant, lipid-lowering, antihypertensive, antidiabetic, antiatherosclerotic, anti-obesity, and hepatoprotective …
Silymarin is the main component of S. marianum and derived from fruits and seeds of S. marianum (milk thistle). S. marianum ha …
Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review.
Soleimani V, Delghandi PS, Moallem SA, Karimi G. Soleimani V, et al. Phytother Res. 2019 Jun;33(6):1627-1638. doi: 10.1002/ptr.6361. Epub 2019 May 8. Phytother Res. 2019. PMID: 31069872 Review.
Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Silymarin is the major constituent of milk thistle extract and is a mixture of some flavonolignans such as silybin, which is the most active component of silymarin. ...
Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Silymarin is the major constituent of milk
The therapeutic potential of milk thistle in diabetes.
Kazazis CE, Evangelopoulos AA, Kollas A, Vallianou NG. Kazazis CE, et al. Rev Diabet Stud. 2014 Summer;11(2):167-74. doi: 10.1900/RDS.2014.11.167. Epub 2014 Aug 10. Rev Diabet Stud. 2014. PMID: 25396404 Free PMC article. Review.
Recently, a substance from milk thistle has been shown to possess peroxisome proliferator-activated receptor γ (PPARγ) agonist properties. ...In this review, the therapeutic potential of milk thistle in the management of diabetes and its complications …
Recently, a substance from milk thistle has been shown to possess peroxisome proliferator-activated receptor γ (PPARγ) agonist …
[Milk Thistle (Silybum Marianum) as a Supportive Phytotherapeutic Agent in Oncology].
Frassová Z, Rudá-Kučerová J. Frassová Z, et al. Klin Onkol. 2017 Winter;30(6):426-432. doi: 10.14735/amko2017426. Klin Onkol. 2017. PMID: 29271213 Review. Czech.
BACKGROUND: Milk thistle (Silybum marianum) has been traditionally used in medicine, particularly in the treatment of liver diseases. ...Based on the results of these studies, milk thistle or silymarin could be beneficial in oncology patients, especial …
BACKGROUND: Milk thistle (Silybum marianum) has been traditionally used in medicine, particularly in the treatment of liver di …
New therapeutic potentials of milk thistle (Silybum marianum).
Milić N, Milosević N, Suvajdzić L, Zarkov M, Abenavoli L. Milić N, et al. Nat Prod Commun. 2013 Dec;8(12):1801-10. Nat Prod Commun. 2013. PMID: 24555302 Review.
Silymarin is a bioflavonoid complex extract derived from dry seeds of Milk thistle [(Silybum marianum(L.) Gaemrnt. (Fam. Asteraceae/Compositaceae)] whose hepatoprotective effect has clinically been proved. ...
Silymarin is a bioflavonoid complex extract derived from dry seeds of Milk thistle [(Silybum marianum(L.) Gaemrnt. (Fam. Aster …
Milk thistle and its derivative compounds: a review of opportunities for treatment of liver disease.
Hackett ES, Twedt DC, Gustafson DL. Hackett ES, et al. J Vet Intern Med. 2013 Jan-Feb;27(1):10-6. doi: 10.1111/jvim.12002. Epub 2012 Nov 9. J Vet Intern Med. 2013. PMID: 23140176 Free article. Review.
Milk thistle extracts have been used as a "liver tonic" for centuries. In recent years, silibinin, the active ingredient in milk thistle extracts, has been studied both in vitro and in vivo to evaluate the beneficial effects in hepatic disease. ...
Milk thistle extracts have been used as a "liver tonic" for centuries. In recent years, silibinin, the active ingredient in
The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity.
Kawaguchi-Suzuki M, Frye RF, Zhu HJ, Brinda BJ, Chavin KD, Bernstein HJ, Markowitz JS. Kawaguchi-Suzuki M, et al. Drug Metab Dispos. 2014 Oct;42(10):1611-6. doi: 10.1124/dmd.114.057232. Epub 2014 Jul 15. Drug Metab Dispos. 2014. PMID: 25028567 Free PMC article. Clinical Trial.
The active constituents of milk thistle supplements are believed to be the flavonolignans contained within the extracts. In vitro studies have suggested that some milk thistle components may significantly inhibit specific cytochrome P450 (P450) enzymes …
The active constituents of milk thistle supplements are believed to be the flavonolignans contained within the extracts. In vi …
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