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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1975 1
1977 1
1979 1
1980 1
1981 5
1983 2
1984 2
1985 2
1986 1
1987 5
1988 9
1989 2
1990 7
1991 11
1992 15
1993 6
1994 2
1995 9
1996 15
1997 18
1998 27
1999 34
2000 41
2001 46
2002 60
2003 60
2004 75
2005 123
2006 141
2007 115
2008 132
2009 134
2010 134
2011 154
2012 169
2013 170
2014 140
2015 133
2016 153
2017 139
2018 115
2019 107
2020 22
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2,241 results
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Page 1
Carnitine transport and fatty acid oxidation.
Longo N, Frigeni M, Pasquali M. Longo N, et al. Biochim Biophys Acta. 2016 Oct;1863(10):2422-35. doi: 10.1016/j.bbamcr.2016.01.023. Epub 2016 Jan 29. Biochim Biophys Acta. 2016. PMID: 26828774 Free PMC article. Review.
Carnitine is accumulated by the cells and retained by kidneys using OCTN2, a high affinity organic cation transporter specific for carnitine. ...
Carnitine is accumulated by the cells and retained by kidneys using OCTN2, a high affinity organic cation transporter specific …
Regulation of organic cation transport.
Ciarimboli G, Schlatter E. Ciarimboli G, et al. Pflugers Arch. 2005 Feb;449(5):423-41. doi: 10.1007/s00424-004-1355-5. Epub 2004 Nov 16. Pflugers Arch. 2005. PMID: 15688244 Review.
Transport of organic cations (OC) is important for the recycling of endogenous OC and also a necessary step for detoxification of exogenous OC in the body. ...Further research is necessary to clarify this important issue of regulation of OC transport....
Transport of organic cations (OC) is important for the recycling of endogenous OC and also a necessary step for detoxification
Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy.
Hörbelt M, Wotzlaw C, Sutton TA, Molitoris BA, Philipp T, Kribben A, Fandrey J, Pietruck F. Hörbelt M, et al. Kidney Int. 2007 Aug;72(4):422-9. doi: 10.1038/sj.ki.5002317. Epub 2007 May 2. Kidney Int. 2007. PMID: 17495857 Free article.
To investigate changes in transport activity, cimetidine, a competitive inhibitor of organic cation transport was co-injected with ASP(+). ...Our studies show that organic cation transport of the kidney can be visualized in vivo by …
To investigate changes in transport activity, cimetidine, a competitive inhibitor of organic cation transport wa …
Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function.
Seth P, Wu X, Huang W, Leibach FH, Ganapathy V. Seth P, et al. J Biol Chem. 1999 Nov 19;274(47):33388-92. doi: 10.1074/jbc.274.47.33388. J Biol Chem. 1999. PMID: 10559218 Free article.
In the present study, we assessed the influence of these two mutations on the carnitine transport function and the organic cation transport function of OCTN2. ...Studies with human OCTN2/rat OCTN2 chimeric transporters indicated that the carnitine t
In the present study, we assessed the influence of these two mutations on the carnitine transport function and the organic
Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides.
van Montfoort JE, Müller M, Groothuis GM, Meijer DK, Koepsell H, Meier PJ. van Montfoort JE, et al. J Pharmacol Exp Ther. 2001 Jul;298(1):110-5. J Pharmacol Exp Ther. 2001. PMID: 11408531
To identify the transport systems involved in type I and type II organic cation uptake, we compared the organic cation transport properties of the rat and human organic cation transporter 1 (rOCT1; hOCT1) and of the organ
To identify the transport systems involved in type I and type II organic cation uptake, we compared the organic
Polyspecific organic cation transport: insights into the substrate binding site.
Burckhardt G. Burckhardt G. Mol Pharmacol. 2005 May;67(5):1391-2. doi: 10.1124/mol.105.012161. Epub 2005 Feb 25. Mol Pharmacol. 2005. PMID: 15737954 Review.
Positively charged endogenous and exogenous organic compounds of diverse chemical structures are transported by polyspecific organic cation transporters (OCT). In two contributions to the May 2005 issue of Molecular Pharmacology, amino acid residues within th …
Positively charged endogenous and exogenous organic compounds of diverse chemical structures are transported by polyspecific organ
Organic Cation Transporters in Health and Disease.
Koepsell H. Koepsell H. Pharmacol Rev. 2020 Jan;72(1):253-319. doi: 10.1124/pr.118.015578. Pharmacol Rev. 2020. PMID: 31852803 Review.
The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN)1, OCTN2, multidrug and toxin exclusion (MATE)1, and MATE kidney-specific 2 are polyspecific transporters exhibiting broadly overlapping substrate selectivities. They transport organi
The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN)1, OCTN2, multidrug and toxin exclusion (MATE)1, and …
Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics.
Wagner DJ, Hu T, Wang J. Wagner DJ, et al. Pharmacol Res. 2016 Sep;111:237-246. doi: 10.1016/j.phrs.2016.06.002. Epub 2016 Jun 16. Pharmacol Res. 2016. PMID: 27317943 Free PMC article. Review.
This review focuses on polyspecific organic cation transporters, which include the organic cation transporters 1-3 (OCT1-3), the multidrug and toxin extrusion proteins 1-2 (MATE1-2) and the plasma membrane monoamine transporter (PMAT). Following an ove …
This review focuses on polyspecific organic cation transporters, which include the organic cation transporters 1 …
Tyrosine 112 is essential for organic cation transport by the plasma membrane monoamine transporter.
Ho HT, Wang J. Ho HT, et al. Biochemistry. 2010 Sep 14;49(36):7839-46. doi: 10.1021/bi100560q. Biochemistry. 2010. PMID: 20687515 Free PMC article.
Plasma membrane monoamine transporter (PMAT) is a polyspecific organic cation transporter in the solute carrier 29 (SLC29) family. ...At position Y85, aromatic substitution with phenylalanine or tryptophan fully restored organic cation transport
Plasma membrane monoamine transporter (PMAT) is a polyspecific organic cation transporter in the solute carrier 29 (SLC29) fam …
Mouse organic cation transporter 1 determines properties and regulation of basolateral organic cation transport in renal proximal tubules.
Schlatter E, Klassen P, Massmann V, Holle SK, Guckel D, Edemir B, Pavenstädt H, Ciarimboli G. Schlatter E, et al. Pflugers Arch. 2014 Aug;466(8):1581-9. doi: 10.1007/s00424-013-1395-9. Pflugers Arch. 2014. PMID: 24233562
The proximal tubule of mouse kidney expresses mouse organic cation transporter 1 (mOCT1), mOCT2, and much less mOCT3. Therefore, mOCT-mediated transport across the basolateral membrane of proximal tubules reflects properties of at least mOCT1 and mOCT2. ...As …
The proximal tubule of mouse kidney expresses mouse organic cation transporter 1 (mOCT1), mOCT2, and much less mOCT3. Therefor …
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