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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1913 1
1921 1
1928 1
1932 1
1946 2
1947 2
1948 1
1949 2
1951 1
1953 1
1954 3
1955 2
1956 2
1957 2
1958 1
1959 5
1960 8
1961 7
1962 8
1963 10
1964 19
1965 12
1966 17
1967 27
1968 25
1969 40
1970 41
1971 53
1972 48
1973 60
1974 87
1975 76
1976 86
1977 95
1978 88
1979 107
1980 113
1981 123
1982 143
1983 166
1984 157
1985 196
1986 239
1987 212
1988 216
1989 290
1990 355
1991 331
1992 357
1993 400
1994 425
1995 499
1996 483
1997 484
1998 564
1999 545
2000 647
2001 673
2002 752
2003 903
2004 899
2005 1078
2006 1163
2007 1118
2008 1213
2009 1224
2010 1366
2011 1487
2012 1594
2013 1596
2014 1700
2015 1794
2016 1680
2017 1687
2018 1827
2019 1824
2020 1436
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31,691 results
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Page 1
Osteoblast-osteoclast interactions.
Chen X, Wang Z, Duan N, Zhu G, Schwarz EM, Xie C. Chen X, et al. Connect Tissue Res. 2018 Mar;59(2):99-107. doi: 10.1080/03008207.2017.1290085. Epub 2017 Mar 21. Connect Tissue Res. 2018. PMID: 28324674 Free PMC article. Review.
Thus, the mechanisms that regulate communication between osteoclasts and osteoblasts are critical to bone cell biology. It has been shown that osteoblasts and osteoclasts can communicate with each other through direct cell-cell contact, cytokines, and extracellular …
Thus, the mechanisms that regulate communication between osteoclasts and osteoblasts are critical to bone cell biology. It has been s …
Recent advances in osteoclast biology.
Ono T, Nakashima T. Ono T, et al. Histochem Cell Biol. 2018 Apr;149(4):325-341. doi: 10.1007/s00418-018-1636-2. Epub 2018 Feb 1. Histochem Cell Biol. 2018. PMID: 29392395 Review.
In order to exert these functions throughout life, bone tissue undergoes a repeating cycle of osteoclastic bone resorption and osteoblastic bone formation. ...This review outlines the findings on osteoclast and RANKL/RANK signaling that have accumulated to date....
In order to exert these functions throughout life, bone tissue undergoes a repeating cycle of osteoclastic bone resorption and osteob …
Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells.
Florencio-Silva R, Sasso GR, Sasso-Cerri E, Simões MJ, Cerri PS. Florencio-Silva R, et al. Biomed Res Int. 2015;2015:421746. doi: 10.1155/2015/421746. Epub 2015 Jul 13. Biomed Res Int. 2015. PMID: 26247020 Free PMC article. Review.
For instance, the coupling from bone resorption to bone formation is achieved by interaction between osteoclasts and osteoblasts. Moreover, osteocytes produce factors that influence osteoblast and osteoclast activities, whereas osteocyte apoptosis is followed by …
For instance, the coupling from bone resorption to bone formation is achieved by interaction between osteoclasts and osteoblasts. Mor …
Osteoclasts and Remodeling Based Bone Formation.
Kylmaoja E, Nakamura M, Tuukkanen J. Kylmaoja E, et al. Curr Stem Cell Res Ther. 2016;11(8):626-633. doi: 10.2174/1574888x10666151019115724. Curr Stem Cell Res Ther. 2016. PMID: 26477623 Review.
Osteoclasts are multinuclear cells of the monocyte macrophage lineage. They are responsible for bone remodeling by first resorbing packets of bone, which are subsequently replaced by new bone produced by osteoblasts. ...It is this osteoclast derived influence on mes
Osteoclasts are multinuclear cells of the monocyte macrophage lineage. They are responsible for bone remodeling by first resorbing pa
Energy metabolism in osteoclast formation and activity.
Lemma S, Sboarina M, Porporato PE, Zini N, Sonveaux P, Di Pompo G, Baldini N, Avnet S. Lemma S, et al. Int J Biochem Cell Biol. 2016 Oct;79:168-180. doi: 10.1016/j.biocel.2016.08.034. Epub 2016 Aug 30. Int J Biochem Cell Biol. 2016. PMID: 27590854
In human osteoclasts derived from the fusion of monocytic precursors, we found a substantial increase in the number of mitochondria with differentiation. ...A better understanding of human osteoclast energy metabolism holds the potential for future therapeutic inter …
In human osteoclasts derived from the fusion of monocytic precursors, we found a substantial increase in the number of mitochondria w …
The Multifaceted Osteoclast; Far and Beyond Bone Resorption.
Drissi H, Sanjay A. Drissi H, et al. J Cell Biochem. 2016 Aug;117(8):1753-6. doi: 10.1002/jcb.25560. Epub 2016 Apr 26. J Cell Biochem. 2016. PMID: 27019318 Review.
Emerging evidence points to novel functions of osteoclasts in controlling bone formation and angiogenesis. Thus, while the concept of a "clastokine" with the potential to regulate osteogenesis during remodeling did not come as a surprise, new evidence provided unique insig …
Emerging evidence points to novel functions of osteoclasts in controlling bone formation and angiogenesis. Thus, while the concept of …
Effects of methylglyoxal on RANKL-induced osteoclast differentiation in RAW264.7 cells.
Suh KS, Chon S, Jung WW, Choi EM. Suh KS, et al. Chem Biol Interact. 2018 Dec 25;296:18-25. doi: 10.1016/j.cbi.2018.09.005. Epub 2018 Sep 12. Chem Biol Interact. 2018. PMID: 30217477
In addition, real-time RT-PCR assay was used to analyse osteoclast-associated genes. MG markedly inhibited RANKL-induced TRAP activity. ...MG had no effect on the bone resorbing activity of osteoclasts. Our findings indicate that MG inhibits TRAP and glyoxalase I ac …
In addition, real-time RT-PCR assay was used to analyse osteoclast-associated genes. MG markedly inhibited RANKL-induced TRAP activit …
Evaluation of efficacy on RANKL induced osteoclast from RAW264.7 cells.
Song C, Yang X, Lei Y, Zhang Z, Smith W, Yan J, Kong L. Song C, et al. J Cell Physiol. 2019 Jul;234(7):11969-11975. doi: 10.1002/jcp.27852. Epub 2018 Dec 4. J Cell Physiol. 2019. PMID: 30515780
Therefore, in the current study, we examined the efficacy of various concentrations of RANKL-treated RAW264.7 for its osteoclastic differentiation with or without pretreated other costimulators such as: LPS and/or M-CSF. ...Overall, our results establishing an optimal meth …
Therefore, in the current study, we examined the efficacy of various concentrations of RANKL-treated RAW264.7 for its osteoclastic di …
The IRF2BP2-KLF2 axis regulates osteoclast and osteoblast differentiation.
Kim I, Kim JH, Kim K, Seong S, Kim N. Kim I, et al. BMB Rep. 2019 Jul;52(7):469-474. doi: 10.5483/BMBRep.2019.52.7.104. BMB Rep. 2019. PMID: 31186082 Free PMC article.
Although the NF-κB pathway plays an important role in the differentiation of osteoclasts and osteoblasts, the role of KLF2 in these bone cells has not yet been fully elucidated. In this study, we demonstrated that KLF2 regulates osteoclast and osteoblast differentia …
Although the NF-κB pathway plays an important role in the differentiation of osteoclasts and osteoblasts, the role of KLF2 in these b …
Tomatidine suppresses osteoclastogenesis and mitigates estrogen deficiency-induced bone mass loss by modulating TRAF6-mediated signaling.
Hu B, Sun X, Yang Y, Ying Z, Meng J, Zhou C, Jiang G, Li S, Wu F, Zhao X, Zhu H, Wu H, Cai X, Shi Z, Yan S. Hu B, et al. FASEB J. 2019 Feb;33(2):2574-2586. doi: 10.1096/fj.201800920R. Epub 2018 Oct 4. FASEB J. 2019. PMID: 30285579
Postmenopausal osteoporosis is initiated by estrogen withdrawal and is characterized mainly by overactivated osteoclastic bone resorption. ...Tomatidine inhibited osteoclast formation in a dose-dependent manner and decreased the expression of osteoclast marke …
Postmenopausal osteoporosis is initiated by estrogen withdrawal and is characterized mainly by overactivated osteoclastic bone resorp …
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