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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 5
1988 8
1989 31
1990 36
1991 33
1992 42
1993 68
1994 106
1995 169
1996 126
1997 132
1998 160
1999 168
2000 179
2001 230
2002 245
2003 285
2004 316
2005 426
2006 448
2007 470
2008 530
2009 562
2010 637
2011 639
2012 682
2013 721
2014 735
2015 724
2016 649
2017 693
2018 702
2019 711
2020 472
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10,762 results
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Page 1
The multiple functions and mechanisms of osteopontin.
Icer MA, Gezmen-Karadag M. Icer MA, et al. Clin Biochem. 2018 Sep;59:17-24. doi: 10.1016/j.clinbiochem.2018.07.003. Epub 2018 Jul 10. Clin Biochem. 2018. PMID: 30003880 Review.
Osteopontin (OPN) is a highly phosphorylated glycophosphoprotein having acidic characteristics and rich in aspartic acid. OPN, a multifunctional protein, has important functions on cardiovascular diseases, cancer, diabetes and kidney stone diseases and in the process of in
Osteopontin (OPN) is a highly phosphorylated glycophosphoprotein having acidic characteristics and rich in aspartic acid. OPN, a mult
Human osteopontin: Potential clinical applications in cancer (Review).
Hao C, Cui Y, Owen S, Li W, Cheng S, Jiang WG. Hao C, et al. Int J Mol Med. 2017 Jun;39(6):1327-1337. doi: 10.3892/ijmm.2017.2964. Epub 2017 Apr 21. Int J Mol Med. 2017. PMID: 28440483 Free PMC article. Review.
Human osteopontin (OPN) is a glycosylated phosphoprotein which is expressed in a variety of tissues in the body. In recent years, accumulating evidence has indicated that the aberrant expression of OPN is closely associated with tumourigensis, progression and most prominen …
Human osteopontin (OPN) is a glycosylated phosphoprotein which is expressed in a variety of tissues in the body. In recent years, acc …
The role of osteopontin in kidney diseases.
Kaleta B. Kaleta B. Inflamm Res. 2019 Feb;68(2):93-102. doi: 10.1007/s00011-018-1200-5. Epub 2018 Nov 19. Inflamm Res. 2019. PMID: 30456594 Review.
BACKGROUND: Osteopontin (OPN) is a pleiotropic glycoprotein expressed in various cell types in animals and in humans, including bone, immune, smooth muscle, epithelial and endothelial cells. ...
BACKGROUND: Osteopontin (OPN) is a pleiotropic glycoprotein expressed in various cell types in animals and in humans, including bone, …
Role of osteopontin in bone remodeling and orthodontic tooth movement: a review.
Singh A, Gill G, Kaur H, Amhmed M, Jakhu H. Singh A, et al. Prog Orthod. 2018 Jun 25;19(1):18. doi: 10.1186/s40510-018-0216-2. Prog Orthod. 2018. PMID: 29938297 Free PMC article. Review.
In this review, most of the known and postulated mechanisms of osteopontin (OPN) and its role in bone remodeling and orthodontic tooth movement are discussed based on available literature. ...
In this review, most of the known and postulated mechanisms of osteopontin (OPN) and its role in bone remodeling and orthodontic toot …
Osteopontin: A Promising Therapeutic Target in Cardiac Fibrosis.
Abdelaziz Mohamed I, Gadeau AP, Hasan A, Abdulrahman N, Mraiche F. Abdelaziz Mohamed I, et al. Cells. 2019 Dec 3;8(12):1558. doi: 10.3390/cells8121558. Cells. 2019. PMID: 31816901 Free PMC article. Review.
Osteopontin (OPN) is recognized for its significant roles in both physiological and pathological processes. Initially, OPN was recognized as a cytokine with pro-inflammatory actions. ...
Osteopontin (OPN) is recognized for its significant roles in both physiological and pathological processes. Initially, OPN was recogn
Osteopontin at the Crossroads of Inflammation and Tumor Progression.
Castello LM, Raineri D, Salmi L, Clemente N, Vaschetto R, Quaglia M, Garzaro M, Gentilli S, Navalesi P, Cantaluppi V, Dianzani U, Aspesi A, Chiocchetti A. Castello LM, et al. Mediators Inflamm. 2017;2017:4049098. doi: 10.1155/2017/4049098. Epub 2017 Jul 9. Mediators Inflamm. 2017. PMID: 28769537 Free PMC article. Review.
In this context, osteopontin (OPN) appears to be a key determinant of the crosstalk between cancer cells and the host microenvironment, which in turn modulates immune evasion. ...
In this context, osteopontin (OPN) appears to be a key determinant of the crosstalk between cancer cells and the host microenvironmen …
The role of osteopontin in the progression of solid organ tumour.
Zhao H, Chen Q, Alam A, Cui J, Suen KC, Soo AP, Eguchi S, Gu J, Ma D. Zhao H, et al. Cell Death Dis. 2018 Mar 2;9(3):356. doi: 10.1038/s41419-018-0391-6. Cell Death Dis. 2018. PMID: 29500465 Free PMC article. Review.
Osteopontin (OPN) is a bone sialoprotein involved in osteoclast attachment to mineralised bone matrix, as well as being a bone matrix protein, OPN is also a versatile protein that acts on various receptors which are associated with different signalling pathways implicated
Osteopontin (OPN) is a bone sialoprotein involved in osteoclast attachment to mineralised bone matrix, as well as being a bone matrix
Osteopontin in Vascular Disease.
Lok ZSY, Lyle AN. Lok ZSY, et al. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):613-622. doi: 10.1161/ATVBAHA.118.311577. Arterioscler Thromb Vasc Biol. 2019. PMID: 30727754 Free PMC article.
OPN (Osteopontin) is a secreted matricellular cytokine that signals through integrin and CD44 receptors, is highly upregulated in acute and chronic inflammatory settings, and has been implicated in physiological and pathophysiologic processes. ...
OPN (Osteopontin) is a secreted matricellular cytokine that signals through integrin and CD44 receptors, is highly upregulated in acu …
Osteocalcin and osteopontin influence bone morphology and mechanical properties.
Bailey S, Karsenty G, Gundberg C, Vashishth D. Bailey S, et al. Ann N Y Acad Sci. 2017 Dec;1409(1):79-84. doi: 10.1111/nyas.13470. Epub 2017 Oct 16. Ann N Y Acad Sci. 2017. PMID: 29044594 Free PMC article.
Osteocalcin (OC) and osteopontin (OPN) are major non-collagenous proteins (NCPs) involved in bone matrix organization and deposition. ...
Osteocalcin (OC) and osteopontin (OPN) are major non-collagenous proteins (NCPs) involved in bone matrix organization and deposition. …
Osteopontin (OPN) as a CSF and blood biomarker for multiple sclerosis: A systematic review and meta-analysis.
Agah E, Zardoui A, Saghazadeh A, Ahmadi M, Tafakhori A, Rezaei N. Agah E, et al. PLoS One. 2018 Jan 18;13(1):e0190252. doi: 10.1371/journal.pone.0190252. eCollection 2018. PLoS One. 2018. PMID: 29346446 Free PMC article. Review.
Accumulating evidence suggest that cerebrospinal fluid (CSF) and peripheral blood concentration of osteopontin (OPN) may have diagnostic and prognostic value in MS. ...
Accumulating evidence suggest that cerebrospinal fluid (CSF) and peripheral blood concentration of osteopontin (OPN) may have diagnos …
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