Role of platelets and platelet receptors in cancer metastasis.
J Hematol Oncol. 2018 Oct 11;11(1):125. doi: 10.1186/s13045-018-0669-2.
J Hematol Oncol. 2018.
PMID: 30305116
Free PMC article.
Review.
Upon tumor cell arrival in the blood, tumor cells immediately activate platelets to form a permissive microenvironment. Platelets protect tumor cells from shear forces and assault of NK cells, recruit myeloid cells by secretion of chemokines, and mediate an a …
Upon tumor cell arrival in the blood, tumor cells immediately activate platelets to form a permissive microenvironment. Pla …